| Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and-independent mechanisms and contributes to drug resistance JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ... Molecular and cellular biology 24 (7), 2875-2889, 2004 | 526 | 2004 |
| Favipiravir at high doses has potent antiviral activity in SARS-CoV-2− infected hamsters, whereas hydroxychloroquine lacks activity SJF Kaptein, S Jacobs, L Langendries, L Seldeslachts, S Ter Horst, ... Proceedings of the National Academy of Sciences 117 (43), 26955-26965, 2020 | 277 | 2020 |
| STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, L Seldeslachts, ... Nature communications 11 (1), 5838, 2020 | 272 | 2020 |
| A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate L Sanchez-Felipe, T Vercruysse, S Sharma, J Ma, V Lemmens, ... Nature 590 (7845), 320-325, 2021 | 171 | 2021 |
| Comparison of doxycycline delivery methods for Tet-inducible gene expression in a subcutaneous xenograft model C Cawthorne, R Swindell, IJ Stratford, C Dive, A Welman Journal of biomolecular techniques: JBT 18 (2), 120, 2007 | 97 | 2007 |
| [18F]DPA-714: Direct Comparison with [11C]PK11195 in a Model of Cerebral Ischemia in Rats H Boutin, C Prenant, R Maroy, J Galea, AD Greenhalgh, A Smigova, ... PloS one 8 (2), e56441, 2013 | 91 | 2013 |
| Visualizing Kinetically Robust CoIII4L6 Assemblies in Vivo: SPECT Imaging of the Encapsulated [99mTc]TcO4– Anion BP Burke, W Grantham, MJ Burke, GS Nichol, D Roberts, I Renard, ... Journal of the American Chemical Society 140 (49), 16877-16881, 2018 | 90 | 2018 |
| Multimodal nanoparticle imaging agents: design and applications BP Burke, C Cawthorne, SJ Archibald Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2017 | 80 | 2017 |
| Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin-and Fas-induced apoptosis GJ Griffiths, MY Koh, VG Brunton, C Cawthorne, NA Reeves, M Greaves, ... Journal of biological chemistry 279 (44), 46113-46121, 2004 | 80 | 2004 |
| REMBI: Recommended Metadata for Biological Images—enabling reuse of microscopy data in biology U Sarkans, W Chiu, L Collinson, MC Darrow, J Ellenberg, D Grunwald, ... Nature methods 18 (12), 1418-1422, 2021 | 77 | 2021 |
| Biodistribution, pharmacokinetics and metabolism of interleukin‐1 receptor antagonist (IL‐1RA) using [18F]‐IL1RA and PET imaging in rats C Cawthorne, C Prenant, A Smigova, P Julyan, R Maroy, K Herholz, ... British journal of pharmacology 162 (3), 659-672, 2011 | 60 | 2011 |
| Automated GMP compliant production of [18F]AlF-NOTA-octreotide T Tshibangu, C Cawthorne, K Serdons, E Pauwels, W Gsell, G Bormans, ... EJNMMI radiopharmacy and chemistry 5, 1-23, 2020 | 53 | 2020 |
| Synthesis, characterization and in vivo evaluation of a magnetic cisplatin delivery nanosystem based on PMAA-graft-PEG copolymers E Voulgari, A Bakandritsos, S Galtsidis, V Zoumpourlis, BP Burke, ... Journal of Controlled Release 243, 342-356, 2016 | 46 | 2016 |
| Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions BP Burke, N Baghdadi, AE Kownacka, S Nigam, GS Clemente, ... Nanoscale 7 (36), 14889-14896, 2015 | 45 | 2015 |
| Characterization of a preclinical PET insert in a 7 tesla MRI scanner: beyond NEMA testing W Gsell, C Molinos, C Correcher, S Belderbos, J Wouters, S Junge, ... Physics in Medicine & Biology 65 (24), 245016, 2020 | 44 | 2020 |
| Imaging Cox‐2 expression in cancer using PET/SPECT radioligands: current status and future directions A Pacelli, J Greenman, C Cawthorne, G Smith Journal of Labelled Compounds and Radiopharmaceuticals 57 (4), 317-322, 2014 | 43 | 2014 |
| Implementation and validation of time-of-flight PET image reconstruction module for listmode and sinogram projection data in the STIR library N Efthimiou, E Emond, P Wadhwa, C Cawthorne, C Tsoumpas, ... Physics in Medicine & Biology 64 (3), 035004, 2019 | 40 | 2019 |
| A caspase-3 ‘death-switch’in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell … KL Simpson, C Cawthorne, C Zhou, CL Hodgkinson, MJ Walker, ... Cell death & disease 4 (5), e613-e613, 2013 | 40 | 2013 |
| New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities S Poty, P Désogère, C Goze, F Boschetti, D Schols, C Cawthorne, ... Dalton Transactions 44 (11), 5004-5016, 2015 | 37 | 2015 |
| Development of PDT/PET Theranostics: Synthesis and Biological Evaluation of an 18F-Radiolabeled Water-Soluble Porphyrin GM Entract, F Bryden, J Domarkas, H Savoie, L Allott, SJ Archibald, ... Molecular pharmaceutics 12 (12), 4414-4423, 2015 | 36 | 2015 |
