Zachary Sailer
Zachary Sailer
Apple Software Engineer | Jupyter Core Maintainer | PhD from Harms Lab, UOregon
Verified email at - Homepage
Cited by
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Detecting high-order epistasis in nonlinear genotype-phenotype maps
ZR Sailer, MJ Harms
Genetics 205 (3), 1079-1088, 2017
High-order epistasis shapes evolutionary trajectories
ZR Sailer, MJ Harms
PLoS computational biology 13 (5), e1005541, 2017
Molecular ensembles make evolution unpredictable
ZR Sailer, MJ Harms
Proceedings of the National Academy of Sciences 114 (45), 11938-11943, 2017
Inferring a complete genotype-phenotype map from a small number of measured phenotypes
ZR Sailer, SH Shafik, RL Summers, A Joule, A Patterson-Robert, ...
PLoS computational biology 16 (9), e1008243, 2020
Uninterpretable interactions: epistasis as uncertainty
ZR Sailer, MJ Harms
BioRxiv, 378489, 2018
Reproducing machine learning research on binder
J Forde, M Bussonnier, FA Fortin, B Granger, T Head, C Holdgraf, ...
Topiary: pruning the manual labor from ancestral sequence reconstruction
KN Orlandi, SR Phillips, ZR Sailer, JL Harman, MJ Harms
Protein Science 32 (2), e4551, 2023
Comparative analysis and ancestral sequence reconstruction of bacterial sortase family proteins generates functional ancestral mutants with different sequence specificities
JD Valgardson, SA Struyvenberg, ZR Sailer, IM Piper, JE Svendsen, ...
Bacteria 1 (2), 121-135, 2022
Exploring the Evolutionary History of Kinetic Stability in the -Lytic Protease Family
CF Nixon, SA Lim, ZR Sailer, IN Zheludev, CL Gee, BA Kelch, MJ Harms, ...
Biochemistry 60 (3), 170-181, 2021
IPython: components for interactive and parallel computing across disciplines.
F Perez, M Bussonnier, JD Frederic, BM Froehle, BE Granger, P Ivanov, ...
AGU Fall Meeting Abstracts 2013, H51R-02, 2013
Using Ancestral Proteins to Probe the Thermodynamic and Kinetic Properties of the Alpha-Lytic Protease Family
C Nixon, SA Lim, Z Sailer, M Harms, S Marqusee
Biophysical Journal 114 (3), 580a, 2018
Molecular Ensembles Shape Evolutionary Trajectories
MJ Harms, ZR Sailer, LC Wheeler
Biophysical Journal 114 (3), 12a, 2018
Predicting Phenotypes in Sparsely Sampled Genotype-Phenotype Maps
ZR Sailer
University of Oregon, 2018
Detecting high-order epistasis in nonlinear
ZR Sailer, MJ Harms
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