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Mark Brimble
Mark Brimble
Postdoctoral Researcher, St Jude Childrens Research Hospital
Verified email at stjude.org
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Cited by
Cited by
Year
Learning and age-related changes in genome-wide H2A. Z binding in the mouse hippocampus
G Stefanelli, AB Azam, BJ Walters, MA Brimble, CP Gettens, ...
Cell reports 22 (5), 1124-1131, 2018
912018
Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium
Z Liu, BJ Walters, T Owen, MA Brimble, KA Steigelman, LL Zhang, ...
Journal of Neuroscience 32 (31), 10530-10540, 2012
772012
New and improved AAVenues: current status of hemophilia B gene therapy
MA Brimble, UM Reiss, AC Nathwani, AM Davidoff
Expert opinion on biological therapy 16 (1), 79-92, 2016
252016
KDM5A regulates a translational program that controls p53 protein expression
D Hu, C Jablonowski, PH Cheng, A AlTahan, C Li, Y Wang, L Palmer, ...
Iscience 9, 84-100, 2018
242018
Off-target expression of cre-dependent adeno-associated viruses in wild-type C57BL/6J mice
JJ Botterill, A Khlaifia, BJ Walters, MA Brimble, HE Scharfman, ...
eneuro 8 (6), 2021
182021
High-Throughput Screening Reveals Alsterpaullone, 2-Cyanoethyl as a Potent p27Kip1 Transcriptional Inhibitor
BJ Walters, W Lin, S Diao, M Brimble, LI Iconaru, J Dearman, A Goktug, ...
PloS one 9 (3), e91173, 2014
182014
The histone chaperone Anp32e regulates memory formation, transcription, and dendritic morphology by regulating steady-state H2A. Z binding in neurons
G Stefanelli, CE Makowski, MA Brimble, M Hall, A Reda, SD Creighton, ...
Cell reports 36 (7), 2021
122021
Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps
MA Brimble, PH Cheng, SM Winston, IL Reeves, A Souquette, Y Spence, ...
Molecular Therapy-Methods & Clinical Development 24, 280-291, 2022
82022
Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice
G Singh, G Stefanelli, K Narkaj, MA Brimble, SD Creighton, TAB McLean, ...
Communications Biology 5 (1), 482, 2022
72022
547. AAV preparations contain contamination from DNA sequences in production plasmids directly outside of the ITRs
MA Brimble, J Zhou, C Morton, M Meagher, AC Nathwani, JT Gray, ...
Molecular Therapy 24, S218-S219, 2016
62016
Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues
G Casey, C Askew, MA Brimble, RJ Samulski, AM Davidoff, C Li, ...
Plos one 15 (11), e0242599, 2020
52020
Stowaways in the cargo: Contaminating nucleic acids in rAAV preparations for gene therapy.
MA Brimble, SM Winston, AM Davidoff
Molecular Therapy, 2023
32023
Spring Forward: ESGCT Trains the Next Generation of Gene and Cell Therapists.
VMA Woods, MA Brimble
Human Gene Therapy 29 (10), 1074-1075, 2018
22018
Author Correction: Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice
G Singh, G Stefanelli, K Narkaj, MA Brimble, SD Creighton, TAB McLean, ...
Communications Biology 5, 2022
12022
The role of the m6A/m demethylase FTO in memory is both task and sex-dependent in mice
AM Leonetti, IR Galluzzo, TAD McLean, G Stefanelli, F Ramnaraign, ...
Neurobiology of Learning and Memory 210, 107903, 2024
2024
Pre-Existing Immunity to a Nucleic Acid Contaminant-Derived Antigen Mediates Transaminitis and Resultant Diminished Transgene Expression in a Mouse Model of Hepatic Recombinant …
MA Brimble, CL Morton, SM Winston, IL Reeves, Y Spence, PH Cheng, ...
Human Gene Therapy, 2024
2024
Role of the histone variant H2A. Z. 1 in memory, transcription, and alternative splicing is mediated by lysine modification
A Reda, LA Hategan, TAB McLean, SD Creighton, JQ Luo, SES Chen, ...
Neuropsychopharmacology, 1-11, 2024
2024
Recombinant P5 Promoter for Use in Reducing DNA Contamination of AAV Preparations
M BRIMBLE, A Davidoff, PH CHENG, C Morton
US Patent App. 17/927,038, 2023
2023
Sex‐specific accumulation and therapeutic effect of the histone variant H2A. Z in Alzheimer˘s disease
SD Creighton, G Stefanelli, MA Brimble, L Hategan, E Collins, J Zakaria, ...
Alzheimer's & Dementia 19, e064832, 2023
2023
Transcription, Translation, and Immunogenic Potential of P5-Associated rAAV Contaminants Post-Infection
MA Brimble, PH Cheng, SM Winston, IL Reeves, A Souquette, Y Spence, ...
MOLECULAR THERAPY 30 (4), 204-204, 2022
2022
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