Kathryn A. Whitehead
Kathryn A. Whitehead
Professor of Chemical Engineering, Carnegie Mellon University
Verified email at - Homepage
Cited by
Cited by
Knocking down barriers: advances in siRNA delivery
KA Whitehead, R Langer, DG Anderson
Nature Reviews Drug Discovery 8 (2), 129-138, 2009
Lipid-like materials for low-dose, in vivo gene silencing
KT Love, KP Mahon, CG Levins, KA Whitehead, W Querbes, JR Dorkin, ...
Proceedings of the National Academy of Sciences 107 (5), 1864-1869, 2010
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
N Chaudhary, D Weissman, KA Whitehead
Nature reviews Drug discovery 20 (11), 817-838, 2021
Tools for translation: non-viral materials for therapeutic mRNA delivery
KA Hajj, KA Whitehead
Nature Reviews Materials 2 (10), 1-17, 2017
Managing diabetes with nanomedicine: challenges and opportunities
O Veiseh, BC Tang, KA Whitehead, DG Anderson, R Langer
Nature Reviews Drug Discovery 14 (1), 45-57, 2015
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation
D Chen, KT Love, Y Chen, AA Eltoukhy, C Kastrup, G Sahay, A Jeon, ...
Journal of the American Chemical Society 134 (16), 6948-6951, 2012
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
KA Whitehead, JR Dorkin, AJ Vegas, PH Chang, O Veiseh, J Matthews, ...
Nature communications 5 (1), 4277, 2014
Materials for oral delivery of proteins and peptides
TD Brown, KA Whitehead, S Mitragotri
Nature Reviews Materials 5 (2), 127-148, 2020
Action and reaction: the biological response to siRNA and its delivery vehicles
RL Kanasty, KA Whitehead, AJ Vegas, DG Anderson
Molecular Therapy 20 (3), 513-524, 2012
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
DJ Siegwart, KA Whitehead, L Nuhn, G Sahay, H Cheng, S Jiang, M Ma, ...
Proceedings of the National Academy of Sciences 108 (32), 12996-13001, 2011
Silencing or stimulation? siRNA delivery and the immune system
KA Whitehead, JE Dahlman, RS Langer, DG Anderson
Annual review of chemical and biomolecular engineering 2, 77-96, 2011
Lipid nanoparticle formulations for enhanced co-delivery of siRNA and mRNA
RL Ball, KA Hajj, J Vizelman, P Bajaj, KA Whitehead
Nano letters 18 (6), 3814-3822, 2018
Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability
NG Lamson, A Berger, KC Fein, KA Whitehead
Nature biomedical engineering 4 (1), 84-96, 2020
Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization
RL Ball, P Bajaj, KA Whitehead
International journal of nanomedicine, 305-315, 2017
Aminoalcohol lipidoids and uses thereof
KP Mahon, KT Love, CG Levins, KA Whitehead, RS Langer, DG Anderson
US Patent 8,450,298, 2013
Branched‐tail lipid nanoparticles potently deliver mRNA in vivo due to enhanced ionization at endosomal pH
KA Hajj, RL Ball, SB Deluty, SR Singh, D Strelkova, CM Knapp, ...
Small 15 (6), 1805097, 2019
Oral delivery of macromolecules using intestinal patches: applications for insulin delivery
K Whitehead, Z Shen, S Mitragotri
Journal of controlled release 98 (1), 37-45, 2004
Safe and effective permeation enhancers for oral drug delivery
K Whitehead, N Karr, S Mitragotri
Pharmaceutical research 25, 1782-1788, 2008
Nanoparticulate cellular patches for cell-mediated tumoritropic delivery
H Cheng, CJ Kastrup, R Ramanathan, DJ Siegwart, M Ma, SR Bogatyrev, ...
ACS nano 4 (2), 625-631, 2010
Advances in drug delivery
BP Timko, K Whitehead, W Gao, DS Kohane, O Farokhzad, D Anderson, ...
Annual Review of Materials Research 41, 1-20, 2011
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