Kathryn A. Whitehead
Kathryn A. Whitehead
Professor of Chemical Engineering, Carnegie Mellon University
Verified email at - Homepage
Cited by
Cited by
Knocking down barriers: advances in siRNA delivery
KA Whitehead, R Langer, DG Anderson
Nature Reviews Drug Discovery 8 (2), 129-138, 2009
Lipid-like materials for low-dose, in vivo gene silencing
KT Love, KP Mahon, CG Levins, KA Whitehead, W Querbes, JR Dorkin, ...
Proceedings of the National Academy of Sciences 107 (5), 1864-1869, 2010
Managing diabetes with nanomedicine: challenges and opportunities
O Veiseh, BC Tang, KA Whitehead, DG Anderson, R Langer
Nature Reviews Drug Discovery 14 (1), 45-57, 2015
Tools for translation: non-viral materials for therapeutic mRNA delivery
KA Hajj, KA Whitehead
Nature Reviews Materials 2 (10), 1-17, 2017
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation
D Chen, KT Love, Y Chen, AA Eltoukhy, C Kastrup, G Sahay, A Jeon, ...
Journal of the American Chemical Society 134 (16), 6948-6951, 2012
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
KA Whitehead, JR Dorkin, AJ Vegas, PH Chang, O Veiseh, J Matthews, ...
Nature communications 5 (1), 4277, 2014
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
N Chaudhary, D Weissman, KA Whitehead
Nature reviews Drug discovery 20 (11), 817-838, 2021
Action and reaction: the biological response to siRNA and its delivery vehicles
RL Kanasty, KA Whitehead, AJ Vegas, DG Anderson
Molecular Therapy 20 (3), 513-524, 2012
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
DJ Siegwart, KA Whitehead, L Nuhn, G Sahay, H Cheng, S Jiang, M Ma, ...
Proceedings of the National Academy of Sciences 108 (32), 12996-13001, 2011
Materials for oral delivery of proteins and peptides
TD Brown, KA Whitehead, S Mitragotri
Nature Reviews Materials 5 (2), 127-148, 2020
Silencing or stimulation? siRNA delivery and the immune system
KA Whitehead, JE Dahlman, RS Langer, DG Anderson
Annual review of chemical and biomolecular engineering 2, 77-96, 2011
Aminoalcohol lipidoids and uses thereof
KP Mahon, KT Love, CG Levins, KA Whitehead, RS Langer, DG Anderson
US Patent 8,450,298, 2013
Oral delivery of macromolecules using intestinal patches: applications for insulin delivery
K Whitehead, Z Shen, S Mitragotri
Journal of controlled release 98 (1), 37-45, 2004
Lipid nanoparticle formulations for enhanced co-delivery of siRNA and mRNA
RL Ball, KA Hajj, J Vizelman, P Bajaj, KA Whitehead
Nano letters 18 (6), 3814-3822, 2018
Advances in drug delivery
BP Timko, K Whitehead, W Gao, DS Kohane, O Farokhzad, D Anderson, ...
Annual Review of Materials Research 41, 1-20, 2011
Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability
NG Lamson, A Berger, KC Fein, KA Whitehead
Nature biomedical engineering 4 (1), 84-96, 2020
Safe and effective permeation enhancers for oral drug delivery
K Whitehead, N Karr, S Mitragotri
Pharmaceutical research 25, 1782-1788, 2008
Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization
RL Ball, P Bajaj, KA Whitehead
International journal of nanomedicine 12, 305, 2017
Nanoparticulate cellular patches for cell-mediated tumoritropic delivery
H Cheng, CJ Kastrup, R Ramanathan, DJ Siegwart, M Ma, SR Bogatyrev, ...
ACS nano 4 (2), 625-631, 2010
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells
TI Novobrantseva, A Borodovsky, J Wong, B Klebanov, M Zafari, K Yucius, ...
Molecular Therapy—Nucleic Acids 1 (1), e4, 2012
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