BCAA catabolism in brown fat controls energy homeostasis through SLC25A44 T Yoneshiro, Q Wang, K Tajima, M Matsushita, H Maki, K Igarashi, Z Dai, ... Nature 572 (7771), 614-619, 2019 | 372 | 2019 |
Dietary capsaicin reduces obesity‐induced insulin resistance and hepatic steatosis in obese mice fed a high‐fat diet JH Kang, G Tsuyoshi, IS Han, T Kawada, YM Kim, R Yu Obesity 18 (4), 780-787, 2010 | 337 | 2010 |
Dual action of isoprenols from herbal medicines on both PPARã and PPARá in 3T3‐L1 adipocytes and HepG2 hepatocytes N Takahashi, T Kawada, T Goto, T Yamamoto, A Taimatsu, N Matsui, ... FEBS letters 514 (2-3), 315-322, 2002 | 271 | 2002 |
Various terpenoids derived from herbal and dietary plants function as PPAR modulators and regulate carbohydrate and lipid metabolism T Goto, N Takahashi, S Hirai, T Kawada PPAR research 2010, 2010 | 230 | 2010 |
Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes [S] T Goto, JY Lee, A Teraminami, YI Kim, S Hirai, T Uemura, H Inoue, ... Journal of lipid research 52 (5), 873-884, 2011 | 225 | 2011 |
Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system M Kim, T Goto, R Yu, K Uchida, M Tominaga, Y Kano, N Takahashi, ... Scientific reports 5 (1), 18013, 2015 | 206 | 2015 |
Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes JY Lee, N Takahashi, M Yasubuchi, YI Kim, H Hashizaki, MJ Kim, ... American Journal of Physiology-Cell Physiology 302 (2), C463-C472, 2012 | 194 | 2012 |
6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-á mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes Y Isa, Y Miyakawa, M Yanagisawa, T Goto, MS Kang, T Kawada, ... Biochemical and biophysical research communications 373 (3), 429-434, 2008 | 193 | 2008 |
Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages S Hirai, YII Kim, T Goto, MS Kang, M Yoshimura, A Obata, R Yu, ... Life sciences 81 (16), 1272-1279, 2007 | 192 | 2007 |
Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation … N Takahashi, T Kawada, T Yamamoto, T Goto, A Taimatsu, N Aoki, ... Journal of Biological Chemistry 277 (19), 16906-16912, 2002 | 184 | 2002 |
Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues T Uemura, S Hirai, N Mizoguchi, T Goto, JY Lee, K Taketani, Y Nakano, ... Molecular nutrition & food research 54 (11), 1596-1608, 2010 | 181 | 2010 |
Diosgenin, the main aglycon of fenugreek, inhibits LXRá activity in HepG2 cells and decreases plasma and hepatic triglycerides in obese diabetic mice T Uemura, T Goto, MS Kang, N Mizoguchi, S Hirai, JY Lee, Y Nakano, ... The Journal of nutrition 141 (1), 17-23, 2011 | 163 | 2011 |
Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in … T Goto, A Teraminami, JY Lee, K Ohyama, K Funakoshi, YI Kim, S Hirai, ... The Journal of nutritional biochemistry 23 (7), 768-776, 2012 | 145 | 2012 |
Quercetin protects against obesity-induced skeletal muscle inflammation and atrophy NH Le, CS Kim, T Park, JHY Park, MK Sung, DG Lee, SM Hong, SY Choe, ... Mediators of inflammation 2014, 2014 | 143 | 2014 |
Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice JH Kang, G Tsuyoshi, H Le Ngoc, HM Kim, TH Tu, HJ Noh, CS Kim, ... Journal of medicinal food 14 (3), 310-315, 2011 | 143 | 2011 |
Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice T Sakamoto, T Nitta, K Maruno, YS Yeh, H Kuwata, K Tomita, T Goto, ... American Journal of Physiology-Endocrinology and Metabolism 310 (8), E676-E687, 2016 | 138 | 2016 |
Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies S Hirai, N Takahashi, T Goto, S Lin, T Uemura, R Yu, T Kawada Mediators of inflammation 2010, 2010 | 136 | 2010 |
Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes K Kuroyanagi, MS Kang, T Goto, S Hirai, K Ohyama, T Kusudo, R Yu, ... Biochemical and Biophysical Research Communications 366 (1), 219-225, 2008 | 132 | 2008 |
Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes T Sakamoto, N Takahashi, Y Sawaragi, S Naknukool, R Yu, T Goto, ... American Journal of Physiology-Cell Physiology 304 (8), C729-C738, 2013 | 125 | 2013 |
Capsaicin inhibits the production of tumor necrosis factor á by LPS-stimulated murine macrophages, RAW 264.7: a PPARã ligand-like action as a novel mechanism JY Park, T Kawada, IS Han, BS Kim, T Goto, N Takahashi, T Fushiki, ... FEBS letters 572 (1-3), 266-270, 2004 | 122 | 2004 |