eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival JR Graff, BW Konicek, RL Lynch, CA Dumstorf, MS Dowless, AM McNulty, ... Cancer research 69 (9), 3866-3873, 2009 | 253 | 2009 |
Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases BW Konicek, JR Stephens, AM McNulty, N Robichaud, RB Peery, ... Cancer research 71 (5), 1849-1857, 2011 | 247 | 2011 |
Participation of mouse DNA polymerase ι in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer CA Dumstorf, AB Clark, Q Lin, GE Kissling, T Yuan, R Kucherlapati, ... Proceedings of the National Academy of Sciences 103 (48), 18083-18088, 2006 | 128 | 2006 |
Participation of mouse DNA polymerase ι in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer CA Dumstorf, AB Clark, Q Lin, GE Kissling, T Yuan, R Kucherlapati, ... Proceedings of the National Academy of Sciences 103 (48), 18083-18088, 2006 | 128 | 2006 |
Targeting the eIF4F translation initiation complex for cancer therapy BW Konicek, CA Dumstorf, JR Graff Cell Cycle 7 (16), 2466-2471, 2008 | 83 | 2008 |
REV1 is implicated in the development of carcinogen-induced lung cancer CA Dumstorf, S Mukhopadhyay, E Krishnan, B Haribabu, WG McGregor Molecular Cancer Research 7 (2), 247-254, 2009 | 64 | 2009 |
Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis CA Dumstorf, BW Konicek, AM McNulty, SH Parsons, L Furic, ... Molecular cancer therapeutics 9 (12), 3158-3163, 2010 | 47 | 2010 |
Abstract LB-302: eIF4E phosphorylation is Mnk-dependent but does not require assembly of the eIF4F translation initiation complex C Hall, C Dumstorf, B Konicek, N Robichaud, A McNulty, S Parsons, ... Cancer Research 74 (19_Supplement), LB-302-LB-302, 2014 | 3 | 2014 |
Abstract LB-302: eIF4E phosphorylation is Mnk-dependent but does not require assembly of the eIF4F translation initiation complex C Hall, C Dumstorf, B Konicek, N Robichaud, A McNulty, S Parsons, ... Cancer Research 74 (19_Supplement), LB-302-LB-302, 2014 | 3 | 2014 |
Disruption of the eIF4F translation initiation complex as a determinant of diffuse large B-cell lymphoma responsiveness to enzastaurin (LY317615. HCl) and its primary … JR Graff, AM McNulty, CA Dumstorf, SH Parsons, BW Konicek, CA Hall Journal of Clinical Oncology 30 (15_suppl), 8082-8082, 2012 | 1 | 2012 |
Phosphorylation of eIF4E is a critical factor in development and progression of breast cancer in women CA Dumstorf, LE Douglass, JA Deddens, TG Lewis, K Darpel, C Gausvik, ... Cancer Research 76 (14_Supplement), 3919-3919, 2016 | | 2016 |
The Direct Anti-Tumor Activity of Enzastaurin (LY317615. HCl) and Its Primary Metabolite (LY326020. HCl) Is Evident in Preclinical DLBCL Models Regardless of Molecular Subtype JR Graff, AM McNulty, C Dumstorf, B Konicek, C Hall, S Parsons Blood 120 (21), 1336, 2012 | | 2012 |
Sensitivity of diffuse large B cell lymphoma cells to Enzastaurin (LY317615. HCl) and its primary metabolite (LY326020) is critically dependent upon disruption of the eIF4F … AM McNulty, CA Dumstorf, CA Dumstorf, SH Parsons, BW Konicek, ... CANCER RESEARCH 72, 2012 | | 2012 |
Abstract LB-235: Sensitivity of diffuse large B cell lymphoma cells to Enzastaurin (LY317615. HCl) and its primary metabolite (LY326020) is critically dependent upon disruption … AM McNulty, CA Dumstorf, CA Dumstorf, SH Parsons, BW Konicek, ... Cancer Research 72 (8_Supplement), LB-235-LB-235, 2012 | | 2012 |
489 Enzastaurin (LY317615. HCl) and Its Primary Metabolite (LY326020. HCl) Exert Antitumor Effects in Diffuse Large B Cell Lymphoma Through Multiple Mechanisms, Most Notably … J Graff, AM McNulty, C Dumstorf, S Parsons, BW Konicek, C Hall European Journal of Cancer, 151-152, 2012 | | 2012 |
Abstract A237: Elevated Mnk kinase activity is associated with malignant progression and reduced patient survival in human prostate cancer and can be therapeutically inhibited … B Konicek, C Hall, C Dumstorf, B Colligan, S Dong, S Na, J Deddens, ... Molecular Cancer Therapeutics 10 (11_Supplement), A237-A237, 2011 | | 2011 |
Elevated eIF4E phosphorylation is associated with advanced malignancy and decreased patient survival and can be therapeutically inhibited by a novel, orally bio-available Mnk … JR Graff, B Konicek, C Dumstorf, S Siwko, B Colligan, JA Deddens, ... CANCER RESEARCH 71, 2011 | | 2011 |
Abstract LB-384: Elevated eIF4E phosphorylation is associated with advanced malignancy and decreased patient survival and can be therapeutically inhibited by a novel, orally … JR Graff, B Konicek, C Dumstorf, S Siwko, B Colligan, JA Deddens, ... Cancer Research 71 (8_Supplement), LB-384-LB-384, 2011 | | 2011 |
Human prostate cancer progression universally involves elevated eIF4E activation coincident with reduced survival: eIF4E ASO treatment suppresses prostate cancer xenograft … J Graff, B Konicek, C Dumstorf, R Lynch, S Weir, D Capen, P Schwier, ... Cancer Research 68 (9_Supplement), LB-118-LB-118, 2008 | | 2008 |
REV1 inhibition reduces the incidence of carcinogen-induced murine lung tumors. CD Dumstorf, SM Mukhopadhyay, WZ Zacharias, WM McGregor ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 48 (7), 623-623, 2007 | | 2007 |