Katerina Hatzi
Katerina Hatzi
Scientist at Genentech
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα gene.com
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Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90
K Moulick, JH Ahn, H Zong, A Rodina, L Cerchietti, EMG DaGama, ...
Nature chemical biology 7 (11), 818, 2011
2362011
Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation
R Catera, GJ Silverman, K Hatzi, T Seiler, S Didier, L Zhang, M Hervé, ...
Molecular medicine 14 (11-12), 665-674, 2008
2202008
Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA
CC Chu, R Catera, K Hatzi, XJ Yan, L Zhang, XB Wang, HM Fales, ...
Blood, The Journal of the American Society of Hematology 112 (13), 5122-5129, 2008
1872008
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo
LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ...
Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009
1712009
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas
LC Cerchietti, EC Lopes, SN Yang, K Hatzi, KL Bunting, LA Tsikitas, ...
Nature medicine 15 (12), 1369-1376, 2009
1652009
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia
C Hurtz, K Hatzi, L Cerchietti, M Braig, E Park, Y Kim, S Herzog, ...
Journal of Experimental Medicine 208 (11), 2163-2174, 2011
1562011
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms
K Hatzi, JP Nance, MA Kroenke, M Bothwell, EK Haddad, A Melnick, ...
Journal of Experimental Medicine 212 (4), 539-553, 2015
1452015
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence
N Darzentas, A Hadzidimitriou, F Murray, K Hatzi, P Josefsson, ...
Leukemia 24 (1), 125-132, 2010
1192010
Immunoglobulin light chain repertoire in chronic lymphocytic leukemia
K Stamatopoulos, C Belessi, A Hadzidimitriou, T Smilevska, E Kalagiakou, ...
Blood 106 (10), 3575-3583, 2005
1182005
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy
LC Cerchietti, K Hatzi, E Caldas-Lopes, SN Yang, ME Figueroa, RD Morin, ...
The Journal of clinical investigation 120 (12), 4569-4582, 2010
1142010
EZH2 and BCL6 cooperate to assemble CBX8-BCOR complex to repress bivalent promoters, mediate germinal center formation and lymphomagenesis
W Béguelin, M Teater, MD Gearhart, MTC Fernández, RL Goldstein, ...
Cancer cell 30 (2), 197-213, 2016
1122016
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters
K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ...
Cell reports 4 (3), 578-588, 2013
1082013
CREBBP inactivation promotes the development of HDAC3-dependent lymphomas
Y Jiang, A Ortega-Molina, H Geng, HY Ying, K Hatzi, S Parsa, D McNally, ...
Cancer discovery 7 (1), 38-53, 2017
1052017
Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis
K Hatzi, A Melnick
Trends in molecular medicine 20 (6), 343-352, 2014
1002014
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms
C Huang, K Hatzi, A Melnick
Nature immunology 14 (4), 380-388, 2013
872013
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis
MW Murphy, AL Sarver, D Rice, K Hatzi, K Ye, A Melnick, LL Heckert, ...
Proceedings of the National Academy of Sciences 107 (30), 13360-13365, 2010
862010
B‐cell chronic lymphocytic leukemia, a clonal disease of B lymphocytes with receptors that vary in specificity for (auto) antigens
N Chiorazzi, K Hatzi, E Albesiano
Annals of the New York Academy of Sciences 1062 (1), 1-12, 2005
762005
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma
MG Cardenas, W Yu, W Beguelin, MR Teater, H Geng, RL Goldstein, ...
The Journal of clinical investigation 126 (9), 3351-3362, 2016
702016
DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation
AY Lai, D Mav, R Shah, SA Grimm, D Phadke, K Hatzi, A Melnick, ...
Genome research 23 (12), 2030-2041, 2013
662013
Multi-tiered reorganization of the genome during B cell affinity maturation anchored by a germinal center-specific locus control region
KL Bunting, TD Soong, R Singh, Y Jiang, W Béguelin, DW Poloway, ...
Immunity 45 (3), 497-512, 2016
552016
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