A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease KD Coon, AJ Myers, DW Craig, JA Webster, JV Pearson, DH Lince, ... Journal of Clinical Psychiatry 68 (4), 613, 2007 | 714 | 2007 |
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies KP Lesch, N Timmesfeld, TJ Renner, R Halperin, C Röser, TT Nguyen, ... Journal of Neural Transmission 115 (11), 1573-1585, 2008 | 477 | 2008 |
Whole-genome analysis of sporadic amyotrophic lateral sclerosis T Dunckley, MJ Huentelman, DW Craig, JV Pearson, S Szelinger, ... New England Journal of Medicine 357 (8), 775-788, 2007 | 313 | 2007 |
GRM7 variants confer susceptibility to age-related hearing impairment RA Friedman, L Van Laer, MJ Huentelman, SS Sheth, E Van Eyken, ... Human molecular genetics 18 (4), 785-796, 2009 | 247 | 2009 |
Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide–polymorphism association studies JV Pearson, MJ Huentelman, RF Halperin, WD Tembe, S Melquist, ... The American Journal of Human Genetics 80 (1), 126-139, 2007 | 184 | 2007 |
Genome-wide linkage analysis of ADHD using high-density SNP arrays: novel loci at 5q13. 1 and 14q12 M Romanos, C Freitag, C Jacob, DW Craig, A Dempfle, TT Nguyen, ... Molecular psychiatry 13 (5), 522-530, 2008 | 137 | 2008 |
Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma WS Liang, W Hendricks, J Kiefer, J Schmidt, S Sekar, J Carpten, ... Genome Research 27 (4), 524-532, 2017 | 124 | 2017 |
Physical characterization of the “immunosignaturing effect” P Stafford, R Halperin, JB Legutki, DM Magee, J Galgiani, SA Johnston Molecular & Cellular Proteomics 11 (4), 2012 | 98 | 2012 |
Sorl1 as an Alzheimer’s disease predisposition gene? JA Webster, AJ Myers, JV Pearson, DW Craig, D Hu-Lince, KD Coon, ... Neurodegenerative Diseases 5 (2), 60-64, 2008 | 97 | 2008 |
Exploring antibody recognition of sequence space through random-sequence peptide microarrays RF Halperin, P Stafford, SA Johnston Molecular & Cellular Proteomics 10 (3), 2011 | 89 | 2011 |
Prospective feasibility trial for genomics-informed treatment in recurrent and progressive glioblastoma SA Byron, NL Tran, RF Halperin, JJ Phillips, JG Kuhn, JF de Groot, ... Clinical Cancer Research 24 (2), 295-305, 2018 | 73 | 2018 |
Quantitation of heteroplasmy of mtDNA sequence variants identified in a population of AD patients and controls by array-based resequencing KD Coon, J Valla, S Szelinger, LE Schneider, TL Niedzielko, KM Brown, ... Mitochondrion 6 (4), 194-210, 2006 | 58 | 2006 |
A method to reduce ancestry related germline false positives in tumor only somatic variant calling RF Halperin, JD Carpten, Z Manojlovic, J Aldrich, J Keats, S Byron, ... BMC medical genomics 10 (1), 1-17, 2017 | 36 | 2017 |
GuiTope: an application for mapping random-sequence peptides to protein sequences RF Halperin, P Stafford, JS Emery, KA Navalkar, SA Johnston BMC bioinformatics 13 (1), 1-8, 2012 | 36 | 2012 |
Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas ME Berens, A Sood, JS Barnholtz-Sloan, JF Graf, S Cho, S Kim, J Kiefer, ... PloS one 14 (12), e0219724, 2019 | 34 | 2019 |
Cognitive dysfunction in NF1 knock-out mice may result from altered vesicular trafficking of APP/DRD3 complex E Donarum, R Halperin, D Stephan, V Narayanan BMC neuroscience 7 (1), 22, 2006 | 33 | 2006 |
Comparative analysis of primary versus relapse/refractory DLBCL identifies shifts in mutation spectrum DM Greenawalt, WS Liang, S Saif, J Johnson, P Todorov, A Dulak, ... Oncotarget 8 (59), 99237, 2017 | 30 | 2017 |
Suppression of calbindin-D28k expression exacerbates SCA1 phenotype in a disease mouse model PJS Vig, J Wei, Q Shao, ME Lopez, R Halperin, J Gerber The Cerebellum 11 (3), 718-732, 2012 | 29 | 2012 |
Improved methods for RNAseq-based alternative splicing analysis RF Halperin, A Hegde, JD Lang, EA Raupach, C Legendre, WS Liang, ... Scientific reports 11 (1), 1-15, 2021 | 27 | 2021 |
Leveraging spatial variation in tumor purity for improved somatic variant calling of archival tumor only samples RF Halperin, WS Liang, S Kulkarni, EE Tassone, J Adkins, D Enriquez, ... Frontiers in oncology 9, 119, 2019 | 21 | 2019 |