Phosphorylation of membrane type 1-matrix metalloproteinase (MT1-MMP) and its vesicle-associated membrane protein 7 (VAMP7)-dependent trafficking facilitate cell invasion and … KC Williams, MG Coppolino Journal of Biological Chemistry 286 (50), 43405-43416, 2011 | 140 | 2011 |
VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion MJ Kean, KC Williams, M Skalski, D Myers, A Burtnik, D Foster, ... Journal of cell science 122 (22), 4089-4098, 2009 | 139 | 2009 |
SNAP23, Syntaxin4, and vesicle-associated membrane protein 7 (VAMP7) mediate trafficking of membrane type 1–matrix metalloproteinase (MT1-MMP) during invadopodium formation and … KC Williams, RE McNeilly, MG Coppolino Molecular biology of the cell 25 (13), 2061-2070, 2014 | 101 | 2014 |
SNARE-dependent interaction of Src, EGFR and â1 integrin regulates invadopodia formation and tumor cell invasion KC Williams, MG Coppolino Journal of cell science 127 (8), 1712-1725, 2014 | 81 | 2014 |
Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples SI Brett, F Lucien, C Guo, KC Williams, Y Kim, PN Durfee, CJ Brinker, ... The Prostate 77 (13), 1335-1343, 2017 | 77 | 2017 |
Quantification of cancer cell extravasation in vivo Y Kim, KC Williams, CT Gavin, E Jardine, AF Chambers, HS Leong Nature protocols 11 (5), 937-948, 2016 | 77 | 2016 |
Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis KC Williams, MA Cepeda, S Javed, K Searle, KM Parkins, AV Makela, ... Oncogene 38 (19), 3598-3615, 2019 | 61 | 2019 |
A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands E Rodrigues, J Jung, H Park, C Loo, S Soukhtehzari, EN Kitova, ... Nature communications 11 (1), 5091, 2020 | 51 | 2020 |
SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases N Bendris, KC Williams, CR Reis, ES Welf, PH Chen, B Lemmers, ... Molecular biology of the cell 27 (9), 1409-1419, 2016 | 50 | 2016 |
Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells MA Cepeda, JJH Pelling, CL Evered, KC Williams, Z Freedman, I Stan, ... Molecular cancer 15, 1-27, 2016 | 49 | 2016 |
Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma RS Padda, FK Deng, SI Brett, CN Biggs, PN Durfee, CJ Brinker, ... The Prostate 79 (6), 592-603, 2019 | 45 | 2019 |
Analytical considerations in nanoscale flow cytometry of extracellular vesicles to achieve data linearity J Gomes, F Lucien, TT Cooper, Y Kim, KC Williams, XY Liao, L Kaufman, ... Thrombosis and haemostasis 118 (09), 1612-1624, 2018 | 43 | 2018 |
Lamellipodium extension and membrane ruffling require different SNARE-mediated trafficking pathways M Skalski, Q Yi, MJ Kean, DW Myers, KC Williams, A Burtnik, ... BMC cell biology 11, 1-17, 2010 | 41 | 2010 |
TBX3 promotes progression of pre‐invasive breast cancer cells by inducing EMT and directly up‐regulating SLUG M Krstic, B Kolendowski, MJ Cecchini, CO Postenka, HM Hassan, ... The Journal of pathology 248 (2), 191-203, 2019 | 38 | 2019 |
SNARE-mediated membrane traffic is required for focal adhesion kinase signaling and Src-regulated focal adhesion turnover M Skalski, N Sharma, K Williams, A Kruspe, MG Coppolino Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (1), 148-158, 2011 | 29 | 2011 |
Invasion and metastasis—recent advances and future challenges AF Chambers, Z Werb Journal of Molecular Medicine 93, 361-368, 2015 | 28 | 2015 |
Triple-negative primary breast tumors induce supportive premetastatic changes in the extracellular matrix and soluble components of the lung microenvironment B Medeiros, D Goodale, C Postenka, LE Lowes, P Kiser, S Hearn, ... Cancers 12 (1), 172, 2020 | 26 | 2020 |
Clinical significance of STEAP1 extracellular vesicles in prostate cancer K Khanna, N Salmond, KS Lynn, HS Leong, KC Williams Prostate cancer and prostatic diseases, 2021 | 24 | 2021 |
Nanoscale flow cytometry for immunophenotyping and quantitating extracellular vesicles in blood plasma N Salmond, K Khanna, GR Owen, KC Williams Nanoscale 13, 2012-2025, 2021 | 24 | 2021 |
Isolation and characterization of extracellular vesicles for clinical applications in cancer–time for standardization? N Salmond, KC Williams Nanoscale Advances 3, 1830-1852, 2021 | 22 | 2021 |