D Le Couteur
D Le Couteur
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Resveratrol improves health and survival of mice on a high-calorie diet
JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ...
Nature 444 (7117), 337-342, 2006
Reducing inappropriate polypharmacy: the process of deprescribing
IA Scott, SN Hilmer, E Reeve, K Potter, D Le Couteur, D Rigby, D Gnjidic, ...
JAMA internal medicine 175 (5), 827-834, 2015
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
KJ Pearson, JA Baur, KN Lewis, L Peshkin, NL Price, N Labinskyy, ...
Cell metabolism 8 (2), 157-168, 2008
Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes
D Gnjidic, SN Hilmer, FM Blyth, V Naganathan, L Waite, MJ Seibel, ...
Journal of clinical epidemiology 65 (9), 989-995, 2012
Aging biology and geriatric clinical pharmacology
AJ McLean, DG Le Couteur
Pharmacological reviews 56 (2), 163-184, 2004
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice
SM Solon-Biet, AC McMahon, JWO Ballard, K Ruohonen, LE Wu, ...
Cell metabolism 19 (3), 418-430, 2014
Loss of muscle strength, mass (sarcopenia), and quality (specific force) and its relationship with functional limitation and physical disability: the Concord Health and Ageing …
NN Hairi, RG Cumming, V Naganathan, DJ Handelsman, DG Le Couteur, ...
Journal of the American Geriatrics Society 58 (11), 2055-2062, 2010
Medication withdrawal trials in people aged 65 years and older
S Iyer, V Naganathan, AJ McLachlan, DG Le Couteur
Drugs & aging 25 (12), 1021-1031, 2008
Parkinson's disease, pesticides, and glutathione transferase polymorphisms
A Menegon, PG Board, AC Blackburn, GD Mellick, DG Le Couteur
The Lancet 352 (9137), 1344-1346, 1998
Benzodiazepines and risk of hip fractures in older people
RG Cumming, DG Le Couteur
CNS drugs 17 (11), 825-837, 2003
Are sirtuins viable targets for improving healthspan and lifespan?
JA Baur, Z Ungvari, RK Minor, DG Le Couteur, R De Cabo
Nature reviews Drug discovery 11 (6), 443-461, 2012
Clinical pharmacology in the geriatric patient
SN Hilmer, AJ McLachlan, DG Le Couteur
Fundamental & clinical pharmacology 21 (3), 217-230, 2007
The aging liver: drug clearance and an oxygen diffusion barrier hypothesis
DG Le Couteur, AJ McLean
Clinical pharmacokinetics 34 (5), 359-373, 1998
High‐risk prescribing and incidence of frailty among older community‐dwelling men
D Gnjidic, SN Hilmer, FM Blyth, V Naganathan, RG Cumming, ...
Clinical Pharmacology & Therapeutics 91 (3), 521-528, 2012
A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome
M Scheibye-Knudsen, SJ Mitchell, EF Fang, T Iyama, T Ward, J Wang, ...
Cell metabolism 20 (5), 840-855, 2014
Pesticides and Parkinson's disease
DG Le Couteur, AJ McLean, MC Taylor, BL Woodham, PG Board
Biomedicine & pharmacotherapy 53 (3), 122-130, 1999
T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells
A Warren, DG Le Couteur, R Fraser, DG Bowen, GW McCaughan, ...
Hepatology 44 (5), 1182-1190, 2006
Political drive to screen for pre-dementia: not evidence based and ignores the harms of diagnosis
DG Le Couteur, J Doust, H Creasey, C Brayne
Bmj 347, 2013
Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes
D Gnjidic, DG Le Couteur, L Kouladjian, SN Hilmer
Clinics in geriatric medicine 28 (2), 237-253, 2012
Clinical pharmacology of analgesic medicines in older people: impact of frailty and cognitive impairment
AJ McLachlan, S Bath, V Naganathan, SN Hilmer, DG Le Couteur, ...
British journal of clinical pharmacology 71 (3), 351-364, 2011
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