p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling AV Budanov, M Karin Cell 134 (3), 451-460, 2008 | 1506 | 2008 |
The antioxidant function of the p53 tumor suppressor AA Sablina, AV Budanov, GV Ilyinskaya, LS Agapova, JE Kravchenko, ... Nature medicine 11 (12), 1306-1313, 2005 | 1353 | 2005 |
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD AV Budanov, AA Sablina, E Feinstein, EV Koonin, PM Chumakov Science 304 (5670), 596-600, 2004 | 895 | 2004 |
Identification of a Novel Hypoxia-Inducible Factor 1-Responsive Gene, RTP801, Involved in Apoptosis T Shoshani, A Faerman, I Mett, E Zelin, T Tenne, S Gorodin, Y Moshel, ... Molecular and cellular biology 22 (7), 2283-2293, 2002 | 695 | 2002 |
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies JH Lee, AV Budanov, EJ Park, R Birse, TE Kim, GA Perkins, K Ocorr, ... Science 327 (5970), 1223-1228, 2010 | 624 | 2010 |
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability AV Budanov, T Shoshani, A Faerman, E Zelin, I Kamer, H Kalinski, ... Oncogene 21 (39), 6017-6031, 2002 | 424 | 2002 |
Sestrins orchestrate cellular metabolism to attenuate aging JH Lee, AV Budanov, M Karin Cell metabolism 18 (6), 792-801, 2013 | 353 | 2013 |
Sestrins inhibit mTORC1 kinase activation through the GATOR complex A Parmigiani, A Nourbakhsh, B Ding, W Wang, YC Kim, K Akopiants, ... Cell reports 9 (4), 1281-1291, 2014 | 337 | 2014 |
Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3 JH Lee, AV Budanov, S Talukdar, EJ Park, HL Park, HW Park, ... Cell metabolism 16 (3), 311-321, 2012 | 310 | 2012 |
Stressin'Sestrins take an aging fight AV Budanov, JH Lee, M Karin EMBO molecular medicine 2 (10), 388-400, 2010 | 243 | 2010 |
Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling AV Budanov Antioxidants & redox signaling 15 (6), 1679-1690, 2011 | 217 | 2011 |
Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart A Morrison, L Chen, J Wang, M Zhang, H Yang, Y Ma, A Budanov, JH Lee, ... The FASEB Journal 29 (2), 408, 2015 | 172 | 2015 |
Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death I Ben-Sahra, B Dirat, K Laurent, A Puissant, P Auberger, A Budanov, ... Cell Death & Differentiation 20 (4), 611-619, 2013 | 163 | 2013 |
The role of tumor suppressor p53 in the antioxidant defense and metabolism AV Budanov Mutant p53 and MDM2 in Cancer, 337-358, 2014 | 149 | 2014 |
Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals J Segalés, E Perdiguero, AL Serrano, P Sousa-Victor, L Ortet, M Jardí, ... Nature communications 11 (1), 189, 2020 | 112 | 2020 |
Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death B Ding, A Parmigiani, AS Divakaruni, K Archer, AN Murphy, AV Budanov Scientific reports 6 (1), 22538, 2016 | 103 | 2016 |
Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma E Oricchio, N Katanayeva, MC Donaldson, S Sungalee, JP Pasion, ... Science translational medicine 9 (396), eaak9969, 2017 | 72 | 2017 |
Cooperation of Two Mutant p53 Alleles Contributes to Fas Resistance of Prostate Carcinoma Cells KV Gurova, OW Rokhlin, AV Budanov, LG Burdelya, PM Chumakov, ... Cancer research 63 (11), 2905-2912, 2003 | 65 | 2003 |
Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells B Zhao, P Shah, AV Budanov, L Qiang, M Ming, A Aplin, DM Sims, YY He Journal of Biological Chemistry 289 (52), 35806-35814, 2014 | 55 | 2014 |
Sestrin2 facilitates death receptor-induced apoptosis in lung adenocarcinoma cells through regulation of XIAP degradation B Ding, A Parmigiani, C Yang, AV Budanov Cell cycle 14 (20), 3231-3241, 2015 | 39 | 2015 |