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Robert Vander Velde
Robert Vander Velde
Sydney Shaffer Lab, University of Pennsylvania
Verified email at upenn.edu
Title
Cited by
Cited by
Year
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
R Vander Velde, N Yoon, V Marusyk, A Durmaz, A Dhawan, ...
Nature communications 11 (1), 2393, 2020
842020
Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature
A Kaznatcheev, R Vander Velde, JG Scott, D Basanta
British journal of cancer 116 (6), 785-792, 2017
602017
Spontaneous cell fusions as a mechanism of parasexual recombination in tumour cell populations
D Miroshnychenko, E Baratchart, MC Ferrall-Fairbanks, RV Velde, ...
Nature Ecology & Evolution 5 (3), 379-391, 2021
522021
Optimal therapy scheduling based on a pair of collaterally sensitive drugs
N Yoon, R Vander Velde, A Marusyk, JG Scott
Bulletin of mathematical biology 80, 1776-1809, 2018
392018
Roadmap on plasticity and epigenetics in cancer
J Foo, D Basanta, RC Rockne, C Strelez, C Shah, K Ghaffarian, ...
Physical biology 19 (3), 031501, 2022
122022
Antifragile therapy
J West, B Desai, M Strobl, L Pierik, RV Velde, C Armagost, R Miles, ...
BioRxiv, 2020.10. 08.331678, 2020
82020
The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium
Y Dou, SJ Goodchild, RV Velde, Y Wu, D Fedida
American Journal of Physiology-Cell Physiology 305 (4), C468-C478, 2013
82013
Understanding the evolutionary games in NSCLC microenvironment
R Bhattacharya, RV Velde, V Marusyk, B Desai, A Kaznatcheev, ...
bioRxiv, 2020.11. 30.404350, 2020
72020
Integrating mutational and nonmutational mechanisms of acquired therapy resistance within the Darwinian paradigm
R Vander Velde, S Shaffer, A Marusyk
Trends in cancer 8 (6), 456-466, 2022
52022
The impact of tumor stromal architecture on therapy response and clinical progression
PM Altrock, N Yoon, JA Bull, H Wu, J Ruiz-Ramírez, D Miroshnychenko, ...
bioRxiv, 451047, 2018
52018
Clonal differences underlie variable responses to sequential and prolonged treatment
DL Schaff, AJ Fasse, PE White, RJ Vander Velde, SM Shaffer
Cell Systems, 2024
12024
Positive ecological interaction between therapy-resistant and sensitive cells, mediated by stromal niche, slows the expansion of resistant subpopulations and promotes tumor …
B Desai, M Robertson-Tessi, R Vander Velde, T Miti, S Yarlagadda, ...
CANCER RESEARCH 84 (3), 2024
2024
Abstract A016: Positive ecological interaction between therapy-resistant and sensitive cells, mediated by stromal niche, slows the expansion of resistant subpopulations and …
B Desai, M Robertson-Tessi, RV Velde, T Miti, S Yarlagadda, R Shah, ...
Cancer Research 84 (3_Supplement_2), A016-A016, 2024
2024
Abstract A026: EGF/EGFR signaling in priming for resistance to BRAF/MEK inhibitors in melanoma
RJ Vander Velde, SM Shaffer
Cancer Research 84 (3_Supplement_2), A026-A026, 2024
2024
Abstract A013: Cell-extrinsic mechanisms of accelerated therapy resistance mediated by altered pharmacokinetics
P Kumar, RV Velde, V Turati, A Marusyk
Cancer Research 84 (3_Supplement_2), A013-A013, 2024
2024
Applying the principles of convexity and concavity to guide treatment scheduling of ALK inhibitors in non-small cell lung cancer
J West, B Desai, M Strobl, L Pierik, RV Velde, M Robertson-Tessi, ...
Cancer Research 83 (7_Supplement), 847-847, 2023
2023
Abstract B016: Selection and reprogramming contribute to the evolution of targeted therapy resistance
RV Velde, S Shaffer
Cancer Research 82 (10_Supplement), B016-B016, 2022
2022
Evolution of Targeted Therapy Resistance in EML4-ALK Positive Non-Small Cell Lung Cancer
R Vander Velde
University of South Florida, 2021
2021
Resistance to ALK targeting therapies as a gradual Darwinian adaptation to inhibitor specific selective pressures
R Vander Velde, N Yoon, V Marusyk, A Dhawan, O Balynska, B Desai, ...
bioRxiv, 504837, 2018
2018
Dark selection for JAK/STAT-inhibitor resistance in chronic myelomonocytic leukemia
A Kaznatcheev, DR Grimes, RV Velde, V Cannataro, E Baratchart, ...
bioRxiv, 211151, 2017
2017
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