Leveraging polygenic functional enrichment to improve GWAS power G Kichaev, G Bhatia, PR Loh, S Gazal, K Burch, MK Freund, A Schoech, ... The American Journal of Human Genetics 104 (1), 65-75, 2019 | 807 | 2019 |
Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture K Hou, KS Burch, A Majumdar, H Shi, N Mancuso, Y Wu, S Sankararaman, ... Nature Genetics 51 (8), 1244-1251, 2019 | 101 | 2019 |
Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits MK Freund, KS Burch, H Shi, N Mancuso, G Kichaev, KM Garske, DZ Pan, ... The American Journal of Human Genetics 103 (4), 535-552, 2018 | 89 | 2018 |
Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification Y Ding, K Hou, KS Burch, S Lapinska, F Privé, B Vilhjálmsson, ... Nature genetics 54 (1), 30-39, 2022 | 76 | 2022 |
Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data H Shi, KS Burch, R Johnson, MK Freund, G Kichaev, N Mancuso, ... The American Journal of Human Genetics 106 (6), 805-817, 2020 | 73 | 2020 |
Efficient variance components analysis across millions of genomes A Pazokitoroudi, Y Wu, KS Burch, K Hou, B Pasaniuc, S Sankararaman Nature Communications 11, 4020, 2020 | 56* | 2020 |
Quantifying the contribution of dominance deviation effects to complex trait variation in biobank-scale data A Pazokitoroudi, AM Chiu, KS Burch, B Pasaniuc, S Sankararaman The American Journal of Human Genetics 108 (5), 799-808, 2021 | 32* | 2021 |
Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative R Johnson, Y Ding, V Venkateswaran, A Bhattacharya, K Boulier, A Chiu, ... Genome medicine 14 (1), 104, 2022 | 31* | 2022 |
Integrative analysis of Dupuytren's disease identifies novel risk locus and reveals a shared genetic etiology with BMI M Major, MK Freund, KS Burch, N Mancuso, M Ng, D Furniss, B Pasaniuc, ... Genetic epidemiology, 2019 | 21 | 2019 |
On powerful GWAS in admixed populations K Hou, A Bhattacharya, R Mester, KS Burch, B Pasaniuc Nature genetics 53 (12), 1631-1633, 2021 | 16 | 2021 |
Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits R Johnson, KS Burch, K Hou, M Paciuc, B Pasaniuc, S Sankararaman PLOS Computational Biology 17 (10), e1009483, 2021 | 15 | 2021 |
Fast estimation of genetic correlation for Biobank-scale data Y Wu, KS Burch, A Ganna, P Pajukanta, B Pasaniuc, S Sankararaman The American Journal of Human Genetics, 2021 | 14 | 2021 |
A two-step approach to testing overall effect of gene-environment interaction for multiple phenotypes A Majumdar, KS Burch, S Sankararaman, B Pasaniuc, WJ Gauderman, ... Bioinformatics 36 (24), 5640–5648, 2020 | 7 | 2020 |
Impact of cross-ancestry genetic architecture on GWASs in admixed populations R Mester, K Hou, Y Ding, G Meeks, KS Burch, A Bhattacharya, BM Henn, ... The American Journal of Human Genetics 110 (6), 927-939, 2023 | 5 | 2023 |
Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes KS Burch, K Hou, Y Ding, Y Wang, S Gazal, H Shi, B Pasaniuc The American Journal of Human Genetics 109 (4), 692-709, 2022 | 4 | 2022 |
Nausea and Vomiting of Pregnancy and HG Risk Genes Associated With Blood Levels, Sleep, Stomach Pain, and Other Traits [23N] MS Fejzo, K Burch, P Mullin, KW MacGibbon, B Pasaniuc Obstetrics & Gynecology 135, 151S-152S, 2020 | 1 | 2020 |
Methods for the Quantitative Characterization of the Genetic Basis of Human Complex Traits KS Burch UCLA, 2021 | | 2021 |