Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states MK Badman, P Pissios, AR Kennedy, G Koukos, JS Flier, E Maratos-Flier Cell metabolism 5 (6), 426-437, 2007 | 1740 | 2007 |
MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis G Koukos, C Polytarchou, JL Kaplan, A Morley–Fletcher, B Gras–Miralles, ... Gastroenterology 145 (4), 842-852. e2, 2013 | 257 | 2013 |
MicroRNA214 is associated with progression of ulcerative colitis, and inhibition reduces development of colitis and colitis-associated cancer in mice C Polytarchou, DW Hommes, T Palumbo, M Hatziapostolou, ... Gastroenterology 149 (4), 981-992. e11, 2015 | 141 | 2015 |
A matrix metalloprotease‐PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis SL Tressel, NC Kaneider, S Kasuda, C Foley, G Koukos, K Austin, ... EMBO molecular medicine 3 (7), 370-384, 2011 | 141 | 2011 |
HDL biogenesis, remodeling, and catabolism VI Zannis, P Fotakis, G Koukos, D Kardassis, C Ehnholm, M Jauhiainen, ... Handb Exp Pharmacol 224, 53-111, 2015 | 136 | 2015 |
Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models SL Tressel, G Koukos, B Tchernychev, SL Jacques, L Covic, A Kuliopulos Cell-Penetrating Peptides: Methods and Protocols, 259-275, 2011 | 111 | 2011 |
Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1 L Dowal, DS Sim, JR Dilks, P Blair, S Beaudry, BM Denker, G Koukos, ... Proceedings of the National Academy of Sciences 108 (7), 2951-2956, 2011 | 84 | 2011 |
Protease-activated receptor-2 modulates protease-activated Receptor-1–driven neointimal hyperplasia LM Sevigny, KM Austin, P Zhang, S Kasuda, G Koukos, S Sharifi, L Covic, ... Arteriosclerosis, thrombosis, and vascular biology 31 (12), e100-e106, 2011 | 83 | 2011 |
Assessment of circulating microRNAs for the diagnosis and disease activity evaluation in patients with ulcerative colitis by using the nanostring technology C Polytarchou, A Oikonomopoulos, S Mahurkar, A Touroutoglou, ... Inflammatory bowel diseases 21 (11), 2533-2539, 2015 | 74 | 2015 |
A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium G Koukos, C Polytarchou, JL Kaplan, A Oikonomopoulos, D Ziring, ... Inflammatory bowel diseases 21 (5), 996-1005, 2015 | 65 | 2015 |
Noncanonical matrix metalloprotease 1–protease-activated receptor 1 signaling drives progression of atherosclerosis R Rana, T Huang, G Koukos, EK Fletcher, SE Turner, A Shearer, ... Arteriosclerosis, thrombosis, and vascular biology 38 (6), 1368-1380, 2018 | 46 | 2018 |
Matrix metalloprotease 1a deficiency suppresses tumor growth and angiogenesis CJ Foley, M Fanjul-Fernández, A Bohm, N Nguyen, A Agarwal, K Austin, ... Oncogene 33 (17), 2264-2272, 2014 | 43 | 2014 |
Allosteric activation of a G protein-coupled receptor with cell-penetrating receptor mimetics P Zhang, AJ Leger, JD Baleja, R Rana, T Corlin, N Nguyen, G Koukos, ... Journal of Biological Chemistry 290 (25), 15785-15798, 2015 | 42 | 2015 |
The carboxy-terminal region of apoA-I is required for the ABCA1-dependent formation of α-HDL but not preβ-HDL particles in vivo A Chroni, G Koukos, A Duka, VI Zannis Biochemistry 46 (19), 5697-5708, 2007 | 40 | 2007 |
Tumor progression locus 2 mediates signal-induced increases in cytoplasmic calcium and cell migration M Hatziapostolou, G Koukos, C Polytarchou, F Kottakis, ... Science signaling 4 (187), ra55-ra55, 2011 | 39 | 2011 |
LCAT can Rescue the Abnormal Phenotype Produced by the Natural ApoA-I Mutations (Leu141Arg)Pisa and (Leu159Arg)FIN G Koukos, A Chroni, A Duka, D Kardassis, VI Zannis Biochemistry 46 (37), 10713-10721, 2007 | 39 | 2007 |
Apolipoprotein L1-specific antibodies detect endogenous APOL1 inside the endoplasmic reticulum and on the plasma membrane of podocytes SJ Scales, N Gupta, AM De Mazière, G Posthuma, CP Chiu, AA Pierce, ... Journal of the American Society of Nephrology 31 (9), 2044-2064, 2020 | 37 | 2020 |
Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with … G Koukos, A Chroni, A Duka, D Kardassis, VI Zannis Biochemical Journal 406 (1), 167-174, 2007 | 36 | 2007 |
Systems biology in inflammatory bowel diseases: ready for prime time C Polytarchou, G Koukos, D Iliopoulos Current opinion in gastroenterology 30 (4), 339-346, 2014 | 34 | 2014 |
Discrete roles of apoA‐I and apoE in the biogenesis of HDL species: lessons learned from gene transfer studies in different mouse models VI Zannis, G Koukos, K Drosatos, A Vezeridis, EE Zanni, KE Kypreos, ... Annals of medicine 40 (sup1), 14-28, 2008 | 34 | 2008 |