| A guide to the composition and functions of the extracellular matrix NK Karamanos, AD Theocharis, Z Piperigkou, D Manou, A Passi, ... The FEBS journal 288 (24), 6850-6912, 2021 | 645 | 2021 |
| Glycosaminoglycans: key players in cancer cell biology and treatment N Afratis, C Gialeli, D Nikitovic, T Tsegenidis, E Karousou, AD Theocharis, ... The FEBS journal 279 (7), 1177-1197, 2012 | 631 | 2012 |
| Syndecans–key regulators of cell signaling and biological functions NA Afratis, D Nikitovic, HAB Multhaupt, AD Theocharis, JR Couchman, ... The FEBS journal 284 (1), 27-41, 2017 | 288 | 2017 |
| Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of proteoglycans SS Skandalis, N Afratis, G Smirlaki, D Nikitovic, AD Theocharis, ... Matrix Biology 35, 182-193, 2014 | 255 | 2014 |
| Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells P Bouris, SS Skandalis, Z Piperigkou, N Afratis, K Karamanou, AJ Aletras, ... Matrix Biology 43, 42-60, 2015 | 198 | 2015 |
| Insights into the key roles of proteoglycans in breast cancer biology and translational medicine AD Theocharis, SS Skandalis, T Neill, HAB Multhaupt, M Hubo, H Frey, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1855 (2), 276-300, 2015 | 167 | 2015 |
| Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion K Kouvidi, A Berdiaki, D Nikitovic, P Katonis, N Afratis, VC Hascall, ... Journal of Biological Chemistry 286 (44), 38509-38520, 2011 | 156 | 2011 |
| Syndecans as modulators and potential pharmacological targets in cancer progression D Barbouri, N Afratis, C Gialeli, DH Vynios, AD Theocharis, ... Frontiers in oncology 4, 4, 2014 | 111 | 2014 |
| Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin‐like growth factor receptor in the expression of cell surface … AI Tsonis, N Afratis, C Gialeli, MI Ellina, Z Piperigkou, SS Skandalis, ... The FEBS journal 280 (10), 2248-2259, 2013 | 69 | 2013 |
| LOXL2 inhibition paves the way for macrophage-mediated collagen degradation in liver fibrosis M Klepfish, T Gross, M Vugman, NA Afratis, S Havusha-Laufer, ... Frontiers in Immunology 11, 480, 2020 | 55 | 2020 |
| The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery NA Afratis, M Klepfish, NK Karamanos, I Sagi Advanced drug delivery reviews 129, 4-15, 2018 | 50 | 2018 |
| Emerging insights into the role of matrix metalloproteases as therapeutic targets in fibrosis NA Afratis, M Selman, A Pardo, I Sagi Matrix Biology 68, 167-179, 2018 | 47 | 2018 |
| IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules NA Afratis, P Bouris, SS Skandalis, HA Multhaupt, JR Couchman, ... Scientific reports 7 (1), 40138, 2017 | 41 | 2017 |
| The role of heparins and nano-heparins as therapeutic tool in breast cancer NA Afratis, K Karamanou, Z Piperigkou, DH Vynios, AD Theocharis Glycoconjugate journal 34, 299-307, 2017 | 37 | 2017 |
| Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules S S Skandalis, A J Aletras, C Gialeli, A D Theocharis, N Afratis, ... Current molecular medicine 12 (8), 1068-1082, 2012 | 23 | 2012 |
| Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules Z Piperigkou, K Karamanou, NA Afratis, P Bouris, C Gialeli, CLR Belmiro, ... Toxicology letters 240 (1), 32-42, 2016 | 22 | 2016 |
| Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma G Heidari-Hamedani, RR Vivès, A Seffouh, NA Afratis, A Oosterhof, ... Cellular Signalling 27 (10), 2054-2067, 2015 | 22 | 2015 |
| FACE analysis as a fast and reliable methodology to monitor the sulfation and total amount of chondroitin sulfate in biological samples of clinical importance E Karousou, A Asimakopoulou, L Monti, V Zafeiropoulou, N Afratis, ... Molecules 19 (6), 7959-7980, 2014 | 15 | 2014 |
| Novel approaches for extracellular matrix targeting in disease treatment NA Afratis, I Sagi The Extracellular Matrix: Methods and Protocols, 261-275, 2019 | 9 | 2019 |
| Collagen I Sagi, NA Afratis Springer New York, 2019 | 8 | 2019 |
Nikos KaramanosProfessor of Biochemistry, University of Patras, Department of Chemistry, GreeceVerified email at upatras.gr
