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Christoffer Norn
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Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5652020
De novo protein design by deep network hallucination
I Anishchenko, SJ Pellock, TM Chidyausiku, TA Ramelot, S Ovchinnikov, ...
Nature 600 (7889), 547-552, 2021
4022021
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges
I Kufareva, V Katritch, RC Stevens, R Abagyan
Structure 22 (8), 1120-1139, 2014
1812014
De novo design of luciferases using deep learning
AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ...
Nature 614 (7949), 774-780, 2023
1592023
Protein sequence design by conformational landscape optimization
C Norn, BIM Wicky, D Juergens, S Liu, D Kim, D Tischer, B Koepnick, ...
Proceedings of the National Academy of Sciences 118 (11), e2017228118, 2021
1412021
Principles for computational design of binding antibodies
D Baran, MG Pszolla, GD Lapidoth, C Norn, O Dym, T Unger, S Albeck, ...
Proceedings of the National Academy of Sciences 114 (41), 10900-10905, 2017
1402017
AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences
GD Lapidoth, D Baran, GM Pszolla, C Norn, A Alon, MD Tyka, ...
Proteins: Structure, Function, and Bioinformatics 83 (8), 1385-1406, 2015
1092015
An enumerative algorithm for de novo design of proteins with diverse pocket structures
B Basanta, MJ Bick, AK Bera, C Norn, CM Chow, LP Carter, I Goreshnik, ...
Proceedings of the National Academy of Sciences 117 (36), 22135-22145, 2020
642020
Computational design of protein self-assembly
CH Norn, I André
Current opinion in structural biology 39, 39-45, 2016
622016
Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)
T Benned-Jensen, S Norn, Christoffer, Laurent, CM Madsen, HM Larsen, ...
The Journal of Biological Chemistry 287, 35470-35483, 2012
502012
Top-down design of protein architectures with reinforcement learning
ID Lutz, S Wang, C Norn, A Courbet, AJ Borst, YT Zhao, A Dosey, L Cao, ...
Science 380 (6642), 266-273, 2023
422023
Mapping the Ca2+ induced structural change in calreticulin
SG Boelt, C Norn, MI Rasmussen, I André, E Čiplys, R Slibinskas, ...
Journal of Proteomics 142, 138-148, 2016
382016
Assessment and challenges of ligand docking into comparative models of G-protein coupled receptors
ED Nguyen, C Norn, T Frimurer, J Meiler
PLoS One 8 (7), e67302, 2013
382013
Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119
MS Engelstoft, C Norn, M Hauge, ...
British Journal of Pharmacology, 2014
352014
High-accuracy modeling of antibody structures by a search for minimum-energy recombination of backbone fragments
CH Norn, G Lapidoth, SJ Fleishman
Proteins 85 (1), 30-38, 2016
262016
Protein sequence design by explicit energy landscape optimization
C Norn, BIM Wicky, D Juergens, S Liu, D Kim, B Koepnick, I Anishchenko, ...
BioRxiv, 2020.07. 23.218917, 2020
212020
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen
R Amon, OC Grant, S Leviatan Ben-Arye, S Makeneni, AK Nivedha, ...
Scientific reports 8 (1), 10786, 2018
152018
A thermodynamic model of protein structure evolution explains empirical amino acid substitution matrices
C Norn, I André, DL Theobald
Protein science 30 (10), 2057-2068, 2021
132021
Mutation-guided unbiased modeling of the fat sensor GPR119 for high-yield agonist screening
C Norn, M Hauge, MS Engelstoft, SH Kim, J Lehmann, RM Jones, ...
Structure 23 (12), 2377-2386, 2015
112015
Computational design of sequence-specific DNA-binding proteins
CJ Glasscock, R Pecoraro, R McHugh, LA Doyle, W Chen, O Boivin, ...
bioRxiv, 2023
62023
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