Rob Christiaan van Wijk
Rob Christiaan van Wijk
Postdoctoral researcher, Pharmacometrics, Department of Pharmaceutical Biosciences, Uppsala
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα farmbio.uu.se - Αρχική σελίδα
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Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude
V Kantae, EHJ Krekels, A Ordas, O González, RC van Wijk, AC Harms, ...
Zebrafish 13 (6), 504-510, 2016
342016
Systems pharmacology of hepatic metabolism in zebrafish larvae
RC van Wijk, EHJ Krekels, T Hankemeier, HP Spaink, PH van der Graaf
Drug Discovery Today: Disease Models 22, 27-34, 2016
212016
Integration of PKPD relationships into benefit–risk analysis
F Bellanti, RC van Wijk, M Danhof, O Della Pasqua
British journal of clinical pharmacology 80 (5), 979-991, 2015
122015
Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies
P Schulthess, RC van Wijk, EHJ Krekels, JWT Yates, HP Spaink, ...
CPT: pharmacometrics & systems pharmacology 7 (5), 285-287, 2018
102018
Development of a population pharmacokinetic model to predict brain distribution and dopamine D2 receptor occupancy of raclopride in non-anesthetized rat
YC Wong, T Ilkova, RC van Wijk, R Hartman, ECM de Lange
European Journal of Pharmaceutical Sciences 111, 514-525, 2018
102018
Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae
RC van Wijk, EHJ Krekels, V Kantae, AC Harms, T Hankemeier, ...
Scientific Reports 9 (1), 2149, 2019
82019
Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol
RC Van Wijk, EHJ Krekels, V Kantae, A Ordas, T Kreling, AC Harms, ...
Journal of Pharmacology and Experimental Therapeutics 371 (1), 15-24, 2019
42019
Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations
RC van Wijk, R Ayoun Alsoud, H Lennernäs, USH Simonsson
Applied Sciences 10 (7), 2376, 2020
32020
Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development
RC Van Wijk, AM van der Sar, EHJ Krekels, T Verboom, HP Spaink, ...
Clinical and Translational Science, 2020
12020
Multi-modal 3d reconstruction and measurements of zebrafish larvae and its organs using axial-view microscopy
Y Guo, RC van Wijk, EHJ Krekels, HP Spaink, PH van der Graaf, ...
2017 IEEE International Conference on Image Processing (ICIP), 2194-2198, 2017
12017
Segmentation-driven Optimization for Iterative Reconstruction in Optical Projection Tomography: An Exploration
X Tang, HAJ Spaink, RC Van Wijk, FJ Verbeek
IEEE Transactions on Computational Imaging, 2020
2020
Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans
RC van Wijk, W Hu, SM Dijkema, DJ van den Berg, J Liu, R Bahi, ...
British Journal of Pharmacology, 0
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