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Manuela Lavorato
Manuela Lavorato
Verified email at mail.med.upenn.edu
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Cited by
Year
Increased mitochondrial nanotunneling activity, induced by calcium imbalance, affects intermitochondrial matrix exchanges
M Lavorato, VR Iyer, W Dewight, RR Cupo, V Debattisti, L Gomez, ...
Proceedings of the National Academy of Sciences 114 (5), E849-E858, 2017
802017
De novo reconstitution reveals the proteins required for skeletal muscle voltage-induced Ca2+ release
S Perni, M Lavorato, KG Beam
Proceedings of the National Academy of Sciences 114 (52), 13822-13827, 2017
702017
Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3
JW Linsley, IU Hsu, L Groom, V Yarotskyy, M Lavorato, EJ Horstick, ...
Proceedings of the National Academy of Sciences 114 (2), E228-E236, 2017
572017
Endosulfan Effects on Rana dalmatina Tadpoles: Quantitative Developmental and Behavioural Analysis
M Lavorato, I Bernabo, A Crescente, M Denoël, S Tripepi, E Brunelli
Archives of environmental contamination and toxicology 64, 253-262, 2013
472013
Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2
M Lavorato, TQ Huang, VR Iyer, S Perni, G Meissner, ...
Journal of muscle research and cell motility 36, 205-214, 2015
242015
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease
S Guha, C Konkwo, M Lavorato, ND Mathew, M Peng, J Ostrovsky, ...
Human Molecular Genetics 28 (11), 1837-1852, 2019
232019
Skeletal muscle microalterations in patients carrying Malignant Hyperthermia-related mutations of the ec coupling machinery
M Lavorato, PK Gupta, PM Hopkins, C Franzini-Armstrong
European Journal of Translational Myology 26 (4), 2016
232016
Elongated mitochondrial constrictions and fission in muscle fatigue
M Lavorato, E Loro, V Debattisti, TS Khurana, C Franzini-Armstrong
Journal of cell science 131 (23), jcs221028, 2018
122018
The structural basis for intermitochondrial communications is fundamentally different in cardiac and skeletal muscle
M Lavorato, F Formenti, C Franzini‐Armstrong
Experimental Physiology 105 (4), 606-612, 2020
82020
Practical solutions to frequent problems encountered in thin sections electron microscopy
M Lavorato, C Franzini-Armstrong
Microscopy Today 25 (3), 40-45, 2017
72017
Dichloroacetate improves mitochondrial function, physiology, and morphology in FBXL4 disease models
M Lavorato, E Nakamaru-Ogiso, ND Mathew, E Herman, N Shah, ...
JCI insight 7 (16), 2022
62022
Dichloroacetate and thiamine improve survival and mitochondrial stress in a C. elegans model of dihydrolipoamide dehydrogenase deficiency
CN Broxton, P Kaur, M Lavorato, S Ganesh, R Xiao, ND Mathew, ...
JCI insight 7 (20), 2022
42022
Comparative analysis of experimental methods to quantify animal activity in caenorhabditis elegans models of mitochondrial disease
M Lavorato, ND Mathew, N Shah, E Nakamaru-Ogiso, MJ Falk
JoVE (Journal of Visualized Experiments), e62244, 2021
42021
Ultrastructure of primary pacemaking cells in rabbit sino‐atrial node cells indicates limited sarcoplasmic reticulum content
R Iyer, O Monfredi, M Lavorato, M Terasaki, C Franzini‐Armstrong
FASEB bioAdvances 2 (2), 106, 2020
22020
A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
M Lavorato, R Iyer, C Franzini-Armstrong
European Journal of Translational Myology 29 (2), 2019
22019
Electron tomography of mitochondrial nanotunnels in a CPVT model with RyR2 loss-of-function mutation
M Lavorato, VR Iyer, YT Zhao, H Valdivia, C Franzini-Armstrong
Biophysical Journal 110 (3), 367a, 2016
22016
Calcium channel dysfunction in a mutant mouse model of malignant hyperthermia (CaV1. 1 R174W)
D Beqollari, CF Romberg, W Feng, JR Lopez, M Lavorato, S Perni, ...
Biophysical Journal 108 (2), 504a, 2015
12015
Mitochondrial Abnormalities in a Mouse CPVT Model with RyR2 Loss-Of-Function Mutation
VR Iyer, M Lavorato, YT Zhao, HH Valdivia, C Franzini-Armstrong
Biophysical Journal 108 (2), 132a, 2015
12015
Novel Development of Magnetic Resonance Imaging to Quantify the Structural Anatomic Growth of Diverse Organs in Adult and Mutant Zebrafish
S Sharma, S Magnitsky, E Reesey, M Schwartz, S Haroon, M Lavorato, ...
Zebrafish 21 (1), 28-38, 2024
2024
The Mevalonate Pathway Is a Therapeutic Target in TP53 Mutant Acute Myeloid Leukemia
S Skuli, G Wertheim, O Riley, M Kruidenier, B Manning, A Salimov, ...
Blood 142, 408, 2023
2023
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