| Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins AM Younss, H Karen, PF Gerrie, K Mohit, LG Marion, CI Thomas, ... Proceedings of the National Academy of Sciences, 2016 | 179 | 2016 |
| Hippo deficiency leads to cardiac dysfunction accompanied by cardiomyocyte dedifferentiation during pressure overload S Ikeda, W Mizushima, S Sciarretta, M Abdellatif, P Zhai, R Mukai, ... Circulation research 124 (2), 292-305, 2019 | 88 | 2019 |
| Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice D Barefield, M Kumar, J Gorham, JG Seidman, CE Seidman, ... Journal of Molecular and Cellular Cardiology 79 (2015), 234-243, 2014 | 71 | 2014 |
| Cardiac Myosin-binding Protein C and Troponin-I Phosphorylation Independently Modulate Myofilament Length-dependent Activation M Kumar, S Govindan, M Zhang, RJ Khairallah, JL Martin, ... The Journal of biological Chemistry 290 (49), 29241, 2015 | 60 | 2015 |
| Contractile dysfunction in a mouse model expressing a heterozygous MYBPC3 mutation associated with hypertrophic cardiomyopathy D Barefield, M Kumar, PP de Tombe, S Sadayappan American Journal of Physiology-Heart and Circulatory Physiology 306 (6 …, 2014 | 57 | 2014 |
| Probenecid Improves Cardiac Function in Patients With Heart Failure With Reduced Ejection Fraction In Vivo and Cardiomyocyte Calcium Sensitivity In Vitro N Robbins, M Gilbert, M Kumar, JW McNamara, P Daly, SE Koch, ... Journal of the American Heart Association: Cardiovascular and …, 2018 | 30 | 2018 |
| Rewiring of 3D chromatin topology orchestrates transcriptional reprogramming and the development of human dilated cardiomyopathy Y Feng, L Cai, W Hong, C Zhang, N Tan, M Wang, C Wang, F Liu, X Wang, ... Circulation 145 (22), 1663-1683, 2022 | 22 | 2022 |
| The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent KM Grimes, DY Barefield, M Kumar, JW McNamara, ST Weintraub, ... Pflügers Archiv - European Journal of Physiology 31 (6768), 1-11, 2017 | 22 | 2017 |
| Impaired right ventricular calcium cycling is an early risk factor in R14del-phospholamban arrhythmias K Haghighi, G Gardner, E Vafiadaki, M Kumar, LC Green, J Ma, ... Journal of Personalized Medicine 11 (6), 502, 2021 | 20 | 2021 |
| Monoclonal Antibody-Based Immunotherapy and Its Role in the Development of Cardiac Toxicity M Kumar, C Thangavel, BC Richard, S Sadayappan Cancers 2021 (13(1)), 86, 2020 | 20 | 2020 |
| Phosphorylation of cardiac myosin–binding protein-C contributes to calcium homeostasis M Kumar, K Haghighi, EG Kranias, S Sadayappan Journal of Biological Chemistry 295 (32), 11275-11291, 2020 | 18 | 2020 |
| Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility TL Lynch IV, M Kumar, JW McNamara, DWD Kuster, M Sivaguru, ... Journal of molecular and cellular cardiology 156, 33-44, 2021 | 17 | 2021 |
| Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy YE Koshman, M Chu, T Kim, O Kalmanson, M Farjah, M Kumar, W Lewis, ... Journal of molecular and cellular cardiology 72 (2014), 281-291, 2014 | 16 | 2014 |
| Genetic, clinical, molecular, and pathogenic aspects of the South Asian–specific polymorphic MYBPC3Δ25bp variant M Arif, P Nabavizadeh, T Song, D Desai, R Singh, S Bazrafshan, M Kumar, ... Biophysical Reviews 12, 1065-1084, 2020 | 13 | 2020 |
| GSK-3β localizes to the cardiac Z-disc to maintain length dependent activation MJ Stachowski-Doll, M Papadaki, TG Martin, W Ma, HM Gong, S Shao, ... Circulation research 130 (6), 871-886, 2022 | 12 | 2022 |
| Myofilament alterations associated with human R14del-phospholamban cardiomyopathy M Kumar, K Haghighi, S Koch, J Rubinstein, F Stillitano, RJ Hajjar, ... International Journal of Molecular Sciences 24 (3), 2675, 2023 | 10 | 2023 |
| Knockout of sorbin and SH3 domain containing 2 (Sorbs2) in cardiomyocytes leads to dilated cardiomyopathy in mice JM McLendon, X Zhang, DS Matasic, M Kumar, OM Koval, IM Grumbach, ... Journal of the American Heart Association 11 (13), e025687, 2022 | 7 | 2022 |
| Rapid Large Scale Purification of Myofilament Proteins using a cleavable His6-tag M zhang, JL Martin, M Kumar, RJ Khairallah, PP Tombe American Journal of Physiology - Heart and Circulatory Physiology, 2015 | 5 | 2015 |
| Multiscale characterization of left ventricle active behavior in the mouse S Neelakantan, M Kumar, EA Mendiola, H Phelan, V Serpooshan, ... Acta biomaterialia 162, 240-253, 2023 | 4 | 2023 |
| Modulation of myosin by cardiac myosin binding protein-C peptides improves cardiac contractility in ex-vivo experimental heart failure models L Hou, M Kumar, P Anand, Y Chen, N El-Bizri, CJ Pickens, WM Seganish, ... Scientific Reports 12 (1), 4337, 2022 | 4 | 2022 |
Sakthivel SadayappanProfessor of Internal Medicine at University of CincinnatiVerified email at ucmail.uc.edu
