Immunochemical analysis of the interaction of p53 with MDM2;--fine mapping of the MDM2 binding site on p53 using synthetic peptides. SM Picksley, B Vojtesek, A Sparks, DP Lane Oncogene 9 (9), 2523-2529, 1994 | 368 | 1994 |
Molecular characterization of the hdm2-p53 interaction A Böttger, V Böttger, C Garcia-Echeverria, P Chène, HK Hochkeppel, ... Journal of molecular biology 269 (5), 744-756, 1997 | 328 | 1997 |
What the papers say: The p53‐mdm2 autoregulatory feedback loop: A paradigm for the regulation of growth control by p53? SM Picksley, DP Lane | 305 | 1993 |
Identification of novel mdm2 binding peptides by phage display. V Böttger, A Böttger, SF Howard, SM Picksley, P Chène, ... Oncogene 13 (10), 2141-2147, 1996 | 279 | 1996 |
Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence PJ Coates, R Nenutil, A McGregor, SM Picksley, DH Crouch, PA Hall, ... Experimental cell research 265 (2), 262-273, 2001 | 271 | 2001 |
Abnormal expression of wild type p53 protein in normal cells of a cancer family patient DM Barnes, CE Gillett, LG Bobrow, AM Hanby, S Mohammed, S Hodgson, ... The Lancet 340 (8814), 259-263, 1992 | 233 | 1992 |
Human hair follicles contain two forms of ATP‐sensitive potassium channels, only one of which is sensitive to minoxidil K Shorter, NP Farjo, SM Picksley, VA Randall1 The FASEB Journal 22 (6), 1725-1736, 2008 | 175 | 2008 |
Repair of DNA double-strand breaks in Escherichia coli K12 requires a functional recN product SM Picksley, PV Attfield, RG Lloyd Molecular and General Genetics MGG 195, 267-274, 1984 | 171 | 1984 |
Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation. ES Hickman, SM Picksley, KH Vousden Oncogene 9 (8), 2177-2181, 1994 | 140 | 1994 |
Inducible expression of a gene specific to the RecF pathway for recombination in Escherichia coli K12 RG Lloyd, SM Picksley, C Prescott Molecular and General Genetics MGG 190, 162-167, 1983 | 128 | 1983 |
Characterization of p53 oligomerization domain mutations isolated from Li–Fraumeni and Li–Fraumeni like family members ME Lomax, DM Barnes, TR Hupp, SM Picksley, RS Camplejohn Oncogene 17 (5), 643-649, 1998 | 121 | 1998 |
p53 and Rb: their cellular roles SM Picksley, DP Lane Current opinion in cell biology 6 (6), 853-858, 1994 | 115 | 1994 |
Inhibitors of the interaction between P53 and MDM2 DP Lane, V Böttger, A Böttger, SM Picksley, HK Hochkeppel, ... US Patent 7,083,983, 2006 | 85 | 2006 |
The prostamide-related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias KG Khidhir, DF Woodward, NP Farjo, BK Farjo, ES Tang, JW Wang, ... The FASEB Journal 27 (2), 557, 2013 | 82 | 2013 |
Increased epidermal functioning wild‐type p53 expression in vitiligo KU Schallreuter, S Behrens‐Williams, TP Khaliq, SM Picksley, EMJ Peters, ... Experimental dermatology 12 (3), 268-277, 2003 | 79 | 2003 |
Two functional assays employed to detect an unusual mutation in the oligomerisation domain of p53 in a Li-Fraumeni like family ME Lomax, DM Barnes, R Gilchrist, SM Picksley, JM Varley, ... Oncogene 14 (15), 1869-1874, 1997 | 78 | 1997 |
Nucleotide sequence and LexA regulation of the Escherichia coli recN gene K Rostas, SJ Morton, SM Picksley, RG Lloyd Nucleic acids research 15 (13), 5041-5049, 1987 | 78 | 1987 |
Cleavage specificity of bacteriophage T4 endonuclease VII and bacteriophage T7 endonuclease I on synthetic branch migratable Holliday junctions SM Picksley, CA Parsons, B Kemper, SC West Journal of molecular biology 212 (4), 723-735, 1990 | 76 | 1990 |
Interruption of binding of MDM2 and P53 protein and therapeutic application thereof SM Picksley, DP Lane US Patent 6,153,391, 2000 | 68 | 2000 |
On the regulation of the p53 tumour suppressor, and its role in the cellular response to DNA damage DP Lane, C Midgley, T Hupp, X Lu, B Vojtesek, SM Picksley Philosophical Transactions of the Royal Society of London. Series B …, 1995 | 63 | 1995 |