Multi-target-directed ligands to combat neurodegenerative diseases A Cavalli, ML Bolognesi, A Minarini, M Rosini, V Tumiatti, M Recanatini, ... Journal of medicinal chemistry 51 (3), 347-372, 2008 | 1271 | 2008 |
A perspective on multi-target drug discovery and design for complex diseases RR Ramsay, MR Popovic-Nikolic, K Nikolic, E Uliassi, ML Bolognesi Clinical and translational medicine 7, 1-14, 2018 | 582 | 2018 |
Insight Into the Kinetic of Amyloid â (1–42) Peptide Self‐Aggregation: Elucidation of Inhibitors¢ Mechanism of Action M Bartolini, C Bertucci, ML Bolognesi, A Cavalli, C Melchiorre, ... ChemBioChem 8 (17), 2152-2161, 2007 | 417 | 2007 |
Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer¢s disease ML Bolognesi, A Cavalli, L Valgimigli, M Bartolini, M Rosini, V Andrisano, ... Journal of medicinal chemistry 50 (26), 6446-6449, 2007 | 313 | 2007 |
Rational approach to discover multipotent anti-Alzheimer drugs M Rosini, V Andrisano, M Bartolini, ML Bolognesi, P Hrelia, A Minarini, ... Journal of medicinal chemistry 48 (2), 360-363, 2005 | 292 | 2005 |
Neglected Tropical Diseases: Multi-Target-Directed Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania A Cavalli, ML Bolognesi Journal of Medicinal Chemistry 52 (23), 7339-7359, 2009 | 277 | 2009 |
Tacrine derivatives and Alzheimer's disease V Tumiatti, A Minarini, ML Bolognesi, A Milelli, M Rosini, C Melchiorre Current medicinal chemistry 17 (17), 1825-1838, 2010 | 269 | 2010 |
Inhibition of acetylcholinesterase, â-amyloid aggregation, and NMDA receptors in Alzheimer¢s disease: a promising direction for the multi-target-directed ligands gold rush M Rosini, E Simoni, M Bartolini, A Cavalli, L Ceccarini, N Pascu, ... Journal of medicinal chemistry 51 (15), 4381-4384, 2008 | 237 | 2008 |
A small molecule targeting the multifactorial nature of Alzheimer's disease A Cavalli, ML Bolognesi, S Capsoni, V Andrisano, M Bartolini, E Margotti, ... ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46, 3689-3692, 2007 | 235 | 2007 |
Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases V Ivasiv, C Albertini, AE Gonçalves, M Rossi, ML Bolognesi Current Topics in Medicinal Chemistry 19 (19), 1694-1711, 2019 | 213 | 2019 |
Multitarget drug discovery and polypharmacology ML Bolognesi, A Cavalli ChemMedChem 11 (12), 1190-1192, 2016 | 213 | 2016 |
Multitarget drug design strategy: quinone–tacrine hybrids designed to block amyloid-â aggregation and to exert anticholinesterase and antioxidant effects E Nepovimova, E Uliassi, J Korabecny, LE Pena-Altamira, S Samez, ... Journal of medicinal chemistry 57 (20), 8576-8589, 2014 | 187 | 2014 |
Imaging of â-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience M Staderini, MA Martín, ML Bolognesi, JC Menéndez Chemical Society Reviews 44 (7), 1807-1819, 2015 | 180 | 2015 |
Alzheimer's disease: new approaches to drug discovery ML Bolognesi, R Matera, A Minarini, M Rosini, C Melchiorre Current opinion in chemical biology 13 (3), 303-308, 2009 | 173 | 2009 |
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer¢s disease ML Bolognesi, A Cavalli, C Melchiorre Neurotherapeutics 6, 152-162, 2009 | 172 | 2009 |
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease ML Bolognesi, R Banzi, M Bartolini, A Cavalli, A Tarozzi, V Andrisano, ... Journal of medicinal chemistry 50 (20), 4882-4897, 2007 | 172 | 2007 |
The Hippo pathway and YAP/TAZ–TEAD protein–protein interaction as targets for regenerative medicine and cancer treatment: Miniperspective M Santucci, T Vignudelli, S Ferrari, M Mor, L Scalvini, ML Bolognesi, ... Journal of medicinal chemistry 58 (12), 4857-4873, 2015 | 169 | 2015 |
Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-â aggregation ML Bolognesi, V Andrisano, M Bartolini, R Banzi, C Melchiorre Journal of medicinal chemistry 48 (1), 24-27, 2005 | 166 | 2005 |
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues ML Bolognesi, M Bartolini, A Cavalli, V Andrisano, M Rosini, A Minarini, ... Journal of medicinal chemistry 47 (24), 5945-5952, 2004 | 161 | 2004 |
Multitarget drug discovery for Alzheimer's disease: triazinones as BACE‐1 and GSK‐3â inhibitors F Prati, A De Simone, P Bisignano, A Armirotti, M Summa, D Pizzirani, ... Angewandte Chemie 127 (5), 1598-1602, 2015 | 149 | 2015 |