Minimizing clonal variation during mammalian cell line engineering for improved systems biology data generation LM Grav, D Sergeeva, JS Lee, I Marin de Mas, NE Lewis, MR Andersen, ... ACS Synthetic Biology 7 (9), 2148-2159, 2018 | 69 | 2018 |
Multicopy targeted integration for accelerated development of high-producing Chinese hamster ovary cells D Sergeeva, GM Lee, LK Nielsen, LM Grav ACS Synthetic Biology 9 (9), 2546-2561, 2020 | 47 | 2020 |
CRISPR/Cas9 as a genome editing tool for targeted gene integration in CHO cells D Sergeeva, JM Camacho-Zaragoza, JS Lee, HF Kildegaard Crispr gene editing: methods and protocols, 213-232, 2019 | 24 | 2019 |
Using titer and titer normalized to confluence are complementary strategies for obtaining Chinese hamster ovary cell lines with high volumetric productivity of etanercept N Pristovšek, HG Hansen, D Sergeeva, N Borth, GM Lee, MR Andersen, ... Biotechnology journal 13 (3), 1700216, 2018 | 20 | 2018 |
CRISPR Toolbox for mammalian cell engineering D Sergeeva, KJ la Cour Karottki, JS Lee, HF Kildegaard Cell Culture Engineering: Recombinant Protein Production, 185-206, 2019 | 3 | 2019 |
Targeted gene integration for improved production of therapeutic proteins in CHO cells D Sergeeva PhD thesis, Novo Nordisk Foundation Center for Biosustainability, 2020 | 1 | 2020 |
Transcriptional response to recombinant protein production in isogenic multi-copy CHO cells G Scapin, LM Grav | | 2023 |