| 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors AH Long, WM Haso, JF Shern, KM Wanhainen, M Murgai, M Ingaramo, ... Nature medicine 21 (6), 581-590, 2015 | 1583 | 2015 |
| CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy TJ Fry, NN Shah, RJ Orentas, M Stetler-Stevenson, CM Yuan, ... Nature medicine 24 (1), 20-28, 2018 | 1239 | 2018 |
| Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors JF Shern, L Chen, J Chmielecki, JS Wei, R Patidar, M Rosenberg, ... Cancer discovery 4 (2), 216-231, 2014 | 688 | 2014 |
| The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation AS Brohl, DA Solomon, W Chang, J Wang, Y Song, S Sindiri, R Patidar, ... PLoS genetics 10 (7), e1004475, 2014 | 420 | 2014 |
| CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity E Jacoby, SM Nguyen, TJ Fountaine, K Welp, B Gryder, H Qin, Y Yang, ... Nature communications 7 (1), 12320, 2016 | 407 | 2016 |
| PAX3–FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ... Cancer Discovery 7 (8), 884-899, 2017 | 251 | 2017 |
| Preclinical development of bivalent chimeric antigen receptors targeting both CD19 and CD22 H Qin, S Ramakrishna, S Nguyen, TJ Fountaine, A Ponduri, ... Molecular Therapy-Oncolytics 11, 127-137, 2018 | 233 | 2018 |
| The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma MJ McBride, JL Pulice, HC Beird, DR Ingram, AR D¢Avino, JF Shern, ... Cancer cell 33 (6), 1128-1141. e7, 2018 | 205 | 2018 |
| KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis M Murgai, W Ju, M Eason, J Kline, DW Beury, S Kaczanowska, ... Nature medicine 23 (10), 1176-1190, 2017 | 186 | 2017 |
| ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins H Van Valkenburgh, JF Shern, JD Sharer, X Zhu, RA Kahn Journal of Biological Chemistry 276 (25), 22826-22837, 2001 | 183 | 2001 |
| Sequential loss of tumor surface antigens following chimeric antigen receptor T-cell therapies in diffuse large B-cell lymphoma H Shalabi, IL Kraft, HW Wang, CM Yuan, B Yates, C Delbrook, ... Haematologica 103 (5), e215, 2018 | 150 | 2018 |
| Modulation of target antigen density improves CAR T-cell functionality and persistence S Ramakrishna, SL Highfill, Z Walsh, SM Nguyen, H Lei, JF Shern, H Qin, ... Clinical Cancer Research 25 (17), 5329-5341, 2019 | 139 | 2019 |
| MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma ME Yohe, BE Gryder, JF Shern, YK Song, HC Chou, S Sindiri, A Mendoza, ... Science translational medicine 10 (448), eaan4470, 2018 | 125 | 2018 |
| Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ... Nature genetics 51 (12), 1714-1722, 2019 | 124 | 2019 |
| Chemical genomics reveals histone deacetylases are required for core regulatory transcription BE Gryder, L Wu, GM Woldemichael, S Pomella, TR Quinn, PMC Park, ... Nature communications 10 (1), 3004, 2019 | 124 | 2019 |
| Genomic classification and clinical outcome in rhabdomyosarcoma: a report from an international consortium JF Shern, J Selfe, E Izquierdo, R Patidar, HC Chou, YK Song, ME Yohe, ... Journal of Clinical Oncology 39 (26), 2859, 2021 | 115 | 2021 |
| Targeting wild-type and mutationally activated FGFR4 in rhabdomyosarcoma with the inhibitor ponatinib (AP24534) SQ Li, AT Cheuk, JF Shern, YK Song, L Hurd, H Liao, JS Wei, J Khan PloS one 8 (10), e76551, 2013 | 111 | 2013 |
| ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter JD Sharer, JF Shern, H Van Valkenburgh, DC Wallace, RA Kahn Molecular biology of the cell 13 (1), 71-83, 2002 | 109 | 2002 |
| MultiDimensional ClinOmics for precision therapy of children and adolescent young adults with relapsed and refractory cancer: a report from the center for cancer research W Chang, AS Brohl, R Patidar, S Sindiri, JF Shern, JS Wei, YK Song, ... Clinical cancer research 22 (15), 3810-3820, 2016 | 107 | 2016 |
| Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of ā-Alzheimer's precursor protein K Hill, Y Li, M Bennett, M McKay, X Zhu, J Shern, E Torre, JJ Lah, AI Levey, ... Journal of Biological Chemistry 278 (38), 36032-36040, 2003 | 101 | 2003 |
Javed KhanDeputy Branch Chief Genetics Branch, Senior Investigator, Center for Cancer Research, NCI, NIHVerified email at mail.nih.gov
