Patricia Rada
Patricia Rada
Instituto de Investigaciones Biomédicas Alberto Sols
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SCF/‚-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner
P Rada, AI Rojo, S Chowdhry, M McMahon, JD Hayes, A Cuadrado
Molecular and cellular biology, 2011
Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/‚-TrCP axis
P Rada, AI Rojo, N Evrard-Todeschi, NG Innamorato, A Cotte, T Jaworski, ...
Molecular and cellular biology 32 (17), 3486-3499, 2012
Redox control of microglial function: molecular mechanisms and functional significance
AI Rojo, G McBean, M Cindric, J Egea, MG López, P Rada, N Zarkovic, ...
Antioxidants & redox signaling 21 (12), 1766-1801, 2014
Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?
P Rada, Á González-Rodríguez, C García-Monzón, ÁM Valverde
Cell death & disease 11 (9), 802, 2020
Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: role of glycogen synthase kinase-3
AI Rojo, ON Medina-Campos, P Rada, A Zúñiga-Toalá, A López-Gazcón, ...
Free Radical Biology and Medicine 52 (2), 473-487, 2012
NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology
AI Rojo, M Pajares, P Rada, A Nuñez, AJ Nevado-Holgado, R Killik, ...
Redox biology 13, 444-451, 2017
Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal celldeath
AI Rojo, P Rada, J Egea, AO Rosa, MG López, A Cuadrado
Molecular and Cellular Neuroscience 39 (1), 125-132, 2008
The PTEN/NRF2 axis promotes human carcinogenesis
AI Rojo, P Rada, M Mendiola, A Ortega-Molina, K Wojdyla, ...
Antioxidants & redox signaling 21 (18), 2498-2514, 2014
SIRT1 controls acetaminophen hepatotoxicity by modulating inflammation and oxidative stress
P Rada, V Pardo, MA Mobasher, I García-Martínez, L Ruiz, ...
Antioxidants & redox signaling 28 (13), 1187-1208, 2018
Hepatic regulation of VLDL receptor by PPAR‚/š and FGF21 modulates non-alcoholic fatty liver disease
M Zarei, E Barroso, X Palomer, J Dai, P Rada, T Quesada-López, ...
Molecular metabolism 8, 117-131, 2018
Protein tyrosine phosphatase 1B modulates GSK3‚/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity
MA Mobasher, Á González-Rodríguez, B Santamaría, S Ramos, ...
Cell death & disease 4 (5), e626-e626, 2013
Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1‐independent manner
Á González‐Rodríguez, B Santamaría, JA Mas‐Gutierrez, P Rada, ...
Molecular nutrition & food research 59 (8), 1431-1442, 2015
Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative stress
ÁJ García-Yagüe, P Rada, AI Rojo, I Lastres-Becker, A Cuadrado
Journal of Biological Chemistry 288 (8), 5506-5517, 2013
Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line
AE Freitas, J Egea, I Buendía, E Navarro, P Rada, A Cuadrado, ...
Molecular neurobiology 51, 1504-1519, 2015
WNT-3A regulates an Axin1/NRF2 complex that regulates antioxidant metabolism in hepatocytes
P Rada, AI Rojo, A Offergeld, GJ Feng, JP Velasco-Martín, ...
Antioxidants & redox signaling 22 (7), 555-571, 2015
Melatonin–sulforaphane hybrid ITH 12674 induces neuroprotection in oxidative stress conditions by a °drug–prodrugĘmechanism of action
J Egea, I Buendia, E Parada, E Navarro, P Rada, A Cuadrado, MG López, ...
British journal of pharmacology 172 (7), 1807-1821, 2015
Insights into extracellular vesicles as biomarker of NAFLD pathogenesis
I Garcia-Martinez, R Alen, P Rada, AM Valverde
Frontiers in Medicine 7, 395, 2020
Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis
Á González-Rodríguez, MP Valdecantos, P Rada, A Addante, I Barahona, ...
Molecular metabolism 7, 132-146, 2018
Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases
I García-Ruiz, NB Ruiz, P Rada, V Pardo, L Ruiz, A Blas-García, ...
Redox biology 26, 101263, 2019
Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans
M Cruces-Sande, R Vila-Bedmar, AC Arcones, A Gonzalez-Rodriguez, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (12†…, 2018
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