| Effective targeted gene ‘knockdown’in zebrafish A Nasevicius, SC Ekker Nature genetics 26 (2), 216-220, 2000 | 3075 | 2000 |
| In vivo genome editing using a high-efficiency TALEN system VM Bedell, Y Wang, JM Campbell, TL Poshusta, CG Starker, RG Krug II, ... Nature 491 (7422), 114-118, 2012 | 1181 | 2012 |
| p53 activation by knockdown technologies ME Robu, JD Larson, A Nasevicius, S Beiraghi, C Brenner, SA Farber, ... PLoS genetics 3 (5), e78, 2007 | 1180 | 2007 |
| Autoproteolysis in hedgehog Protein Biogenesis JJ Lee, SC Ekker, DP Von Kessler, JA Porter, BI Sun, PA Beachy Science 266 (5190), 1528-1537, 1994 | 705 | 1994 |
| Patterning activities of vertebrate hedgehog proteins in the developing eye and brain SC Ekker, AR Ungar, P Greenstein, DP von Kessler, JA Porter, RT Moon, ... Current biology 5 (8), 944-955, 1995 | 692 | 1995 |
| The product of hedgehog autoproteolytic cleavage active in local and long-range signalling JA Porter, DP von Kessler, SC Ekker, KE Young, JJ Lee, K Moses, ... Nature 374 (6520), 363-366, 1995 | 689 | 1995 |
| Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain JA Porter, SC Ekker, WJ Park, DP Von Kessler, KE Young, CH Chen, ... Cell 86 (1), 21-34, 1996 | 641 | 1996 |
| A primer for morpholino use in zebrafish BR Bill, AM Petzold, KJ Clark, LA Schimmenti, SC Ekker Zebrafish, 2022 | 615 | 2022 |
| Twisted gastrulation is a conserved extracellular BMP antagonist JJ Ross, O Shimmi, P Vilmos, A Petryk, H Kim, K Gaudenz, S Hermanson, ... Nature 410 (6827), 479-483, 2001 | 362 | 2001 |
| Guidelines for morpholino use in zebrafish DYR Stainier, E Raz, ND Lawson, SC Ekker, RD Burdine, JS Eisen, ... PLoS genetics 13 (10), e1007000, 2017 | 359 | 2017 |
| Harnessing a high cargo-capacity transposon for genetic applications in vertebrates D Balciunas, KJ Wangensteen, A Wilber, J Bell, A Geurts, S Sivasubbu, ... PLoS genetics 2 (11), e169, 2006 | 358 | 2006 |
| Morphant technology in model developmental systems SC Ekker, JD Larson genesis 30 (3), 89-93, 2001 | 344 | 2001 |
| Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant A Nasevicius, J Larson, SC Ekker Yeast 1 (4), 294-301, 2000 | 292 | 2000 |
| Efficient gene delivery and gene expression in zebrafish using the Sleeping Beauty transposon AE Davidson, D Balciunas, D Mohn, J Shaffer, S Hermanson, ... Developmental biology 263 (2), 191-202, 2003 | 291 | 2003 |
| WNT5A mutations in patients with autosomal dominant Robinow syndrome AD Person, S Beiraghi, CM Sieben, S Hermanson, AN Neumann, ... Developmental dynamics: an official publication of the American Association …, 2010 | 269 | 2010 |
| Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis SC Ekker, L Lynn McGrew, CJ Lai, JJ Lee, DP von Kessler, RT Moon, ... Development 121 (8), 2337-2347, 1995 | 268 | 1995 |
| Mammalian germ-line transgenesis by transposition AJ Dupuy, K Clark, CM Carlson, S Fritz, AE Davidson, KM Markley, ... Proceedings of the National Academy of Sciences 99 (7), 4495-4499, 2002 | 257 | 2002 |
| The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins. SC Ekker, DG Jackson, DP Von Kessler, BI Sun, KE Young, PA Beachy The EMBO journal 13 (15), 3551-3560, 1994 | 256 | 1994 |
| Morphants: a new systematic vertebrate functional genomics approach SC Ekker Yeast 1 (4), 302-306, 2000 | 238 | 2000 |
| Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila. SC Ekker, KE Young, DP von Kessler, PA Beachy The EMBO journal 10 (5), 1179-1186, 1991 | 231 | 1991 |
Karl J. ClarkAssociate Professor of Biochemistry and Molecular Biology, Mayo ClinicVerified email at mayo.edu
