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Lilia Leisle
Lilia Leisle
Weill Cornell Medicine
Verified email at med.cornell.edu
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Year
ClC‐7 is a slowly voltage‐gated 2Cl−/1H+‐exchanger and requires Ostm1 for transport activity
L Leisle, CF Ludwig, FA Wagner, TJ Jentsch, T Stauber
The EMBO Journal 30 (11), 2140-2152, 2011
2272011
Recurrent Stroke Due to a Novel Voltage Sensor Mutation in Cav2.1 Responds to Verapamil
E Knierim, L Leisle, C Wagner, B Weschke, B Lucke, G Bohner, JP Dreier, ...
Stroke 42 (2), e14-e17, 2011
472011
Incorporation of non-canonical amino acids
L Leisle, F Valiyaveetil, RA Mehl, CA Ahern
Novel Chemical Tools to Study Ion Channel Biology, 119-151, 2015
452015
Common gating of both CLC transporter subunits underlies voltage-dependent activation of the 2Cl−/1H+ exchanger ClC-7/Ostm1
CF Ludwig, F Ullrich, L Leisle, T Stauber, TJ Jentsch
Journal of Biological Chemistry 288 (40), 28611-28619, 2013
422013
Atomic determinants of BK channel activation by polyunsaturated fatty acids
Y Tian, M Aursnes, TV Hansen, JE Tungen, JD Galpin, L Leisle, CA Ahern, ...
Proceedings of the National Academy of Sciences 113 (48), 13905-13910, 2016
382016
Angiotensin-converting enzyme as a GPIase: a critical reevaluation
L Leisle, ET Parkin, AJ Turner, NM Hooper
Nature medicine 11 (11), 1139-1140, 2005
382005
Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b
I Kadurin, A Golubovic, L Leisle, H Schindelin, S Gründer
Biochemical Journal 412 (3), 469-475, 2008
332008
Analysis of CLCN2 as Candidate Gene for Megalencephalic Leukoencephalopathy with Subcortical Cysts
GC Scheper, CGM van Berkel, L Leisle, KE de Groot, A Errami, TJ Jentsch, ...
Genetic testing and molecular biomarkers 14 (2), 255-257, 2010
302010
Cellular encoding of Cy dyes for single-molecule imaging
L Leisle, R Chadda, JD Lueck, DT Infield, JD Galpin, V Krishnamani, ...
Elife 5, e19088, 2016
272016
Probing the conformation of a conserved glutamic acid within the Cl pathway of a CLC H+/Cl exchanger
M Vien, D Basilio, L Leisle, A Accardi
Journal of General Physiology 149 (4), 523-529, 2017
212017
Divergent Cl- and H+ pathways underlie transport coupling and gating in CLC exchangers and channels
L Leisle, Y Xu, E Fortea, S Lee, JD Galpin, M Vien, CA Ahern, A Accardi, ...
Elife 9, e51224, 2020
172020
SUPPLEMENTARY INFORMATION TO
L Leisle, CF Ludwig, FA Wagner, TJ Jentsch, T Stauber
162022
Cross-kingdom auxiliary subunit modulation of a voltage-gated sodium channel
S Molinarolo, S Lee, L Leisle, JD Lueck, D Granata, V Carnevale, ...
Journal of Biological Chemistry 293 (14), 4981-4992, 2018
102018
Dynorphin neuropeptides decrease apparent proton affinity of ASIC1a by occluding the acidic pocket
L Leisle, M Margreiter, A Ortega-Ramírez, E Cleuvers, M Bachmann, ...
Journal of medicinal chemistry 64 (18), 13299-13311, 2021
82021
Backbone amides are determinants of Cl selectivity in CLC ion channels
L Leisle, K Lam, S Dehghani-Ghahnaviyeh, E Fortea, JD Galpin, ...
Nature communications 13 (1), 7508, 2022
22022
Efficient expression of a cnidarian peptide-gated ion channel in mammalian cells
M Bachmann, A Ortega-Ramírez, L Leisle, S Gründer
Channels 15 (1), 273-283, 2021
22021
Backbone amides are key determinants of Cl selectivity in CLC ion channels
L Leisle, K Lam, S Dehghani-Ghahnaviyeh, E Fortea, J Galpin, CA Ahern, ...
bioRxiv, 2022.07. 01.498497, 2022
2022
Mapping the binding site of the opioid neuropeptide Big Dynorphin on ASIC1a
L Leisle, MA Margreiter, G Rossetti, S Gruender
ACTA PHYSIOLOGICA 227, 2019
2019
Backbone Amide Nitrogen Atoms are Key Determinants of Inter-Anion Discrimination in CLCs
L Leisle, E Fortea, J Galpin, C Ahern, A Accardi
Biophysical Journal 114 (3), 493a, 2018
2018
Genetically Encoding Single-Molecule Fluorophores into Ion Channels in Living Cells
L Leisle, R Chadda, JD Galpin, JL Robertson, CA Ahern
Biophysical journal 110 (3), 34a, 2016
2016
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