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sir stephen o'rahilly
sir stephen o'rahilly
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα medschl.cam.ac.uk - Αρχική σελίδα
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Genetic studies of body mass index yield new insights for obesity biology
AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ...
Nature 518 (7538), 197-206, 2015
45812015
Congenital leptin deficiency is associated with severe early-onset obesity in humans
CT Montague, IS Farooqi, JP Whitehead, MA Soos, H Rau, NJ Wareham, ...
Nature 387 (6636), 903-908, 1997
40881997
Biological, clinical and population relevance of 95 loci for blood lipids
TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ...
Nature 466 (7307), 707-713, 2010
40082010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ...
Nature genetics 42 (11), 937-948, 2010
35052010
The GPR54 Gene as a Regulator of Puberty
SB Seminara, S Messager, EE Chatzidaki, RR Thresher, JS Acierno Jr, ...
New England Journal of Medicine 349 (17), 1614-1627, 2003
29772003
Discovery and refinement of loci associated with lipid levels
Nature genetics 45 (11), 1274-1283, 2013
28882013
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105-116, 2010
24762010
Effects of recombinant leptin therapy in a child with congenital leptin deficiency
IS Farooqi, SA Jebb, G Langmack, E Lawrence, CH Cheetham, ...
New England journal of medicine 341 (12), 879-884, 1999
24541999
Hundreds of variants clustered in genomic loci and biological pathways affect human height
H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ...
Nature 467 (7317), 832-838, 2010
22912010
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ...
Nature 478 (7367), 103-109, 2011
22752011
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC ...
Nature genetics 44 (9), 981-990, 2012
21292012
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173-1186, 2014
20592014
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
Nature genetics 41 (1), 25-34, 2009
20482009
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
JJ Lee, R Wedow, A Okbay, E Kong, O Maghzian, M Zacher, ...
Nature genetics 50 (8), 1112-1121, 2018
20442018
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
IS Farooqi, JM Keogh, GSH Yeo, EJ Lank, T Cheetham, S O'Rahilly
New England Journal of Medicine 348 (12), 1085-1095, 2003
20302003
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
IS Farooqi, G Matarese, GM Lord, JM Keogh, E Lawrence, C Agwu, ...
The Journal of clinical investigation 110 (8), 1093-1103, 2002
20112002
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
T Gerken, CA Girard, YCL Tung, CJ Webby, V Saudek, KS Hewitson, ...
Science 318 (5855), 1469-1472, 2007
17762007
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
I Barroso, M Gurnell, VEF Crowley, M Agostini, JW Schwabe, MA Soos, ...
Nature 402 (6764), 880-883, 1999
17671999
New genetic loci link adipose and insulin biology to body fat distribution
D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ...
Nature 518 (7538), 187-196, 2015
15832015
Common variants near MC4R are associated with fat mass, weight and risk of obesity
RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ...
Nature genetics 40 (6), 768-775, 2008
15612008
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