Lefkos Middleton
Lefkos Middleton
Professor of Neurology, Imperial College London
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα ic.ac.uk
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
SH Lee, S Ripke, BM Neale, SV Faraone, SM Purcell, RH Perlis, ...
Nature genetics 45 (9), 984, 2013
18002013
A mega-analysis of genome-wide association studies for major depressive disorder
S Ripke, NR Wray, CM Lewis, SP Hamilton, MM Weissman, G Breen, ...
Molecular psychiatry 18 (4), 497, 2013
10392013
Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis
KY Chan, W Wang, JJ Wu, L Liu, E Theodoratou, J Car, L Middleton, ...
The Lancet 381 (9882), 2016-2023, 2013
6602013
Meta-analysis and imputation refines the association of 15q25 with smoking quantity
JZ Liu, F Tozzi, DM Waterworth, SG Pillai, P Muglia, L Middleton, ...
Nature genetics 42 (5), 436-440, 2010
6202010
Mutations in the dystrophin-associated protein γ-sarcoglycan in chromosome 13 muscular dystrophy
S Noguchi, EM McNally, KB Othmane, Y Hagiwara, Y Mizuno, M Yoshida, ...
Science 270 (5237), 819-822, 1995
5981995
Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease
JM Van Der Walt, KK Nicodemus, ER Martin, WK Scott, MA Nance, ...
The American Journal of Human Genetics 72 (4), 804-811, 2003
5902003
Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V
A Antonellis, RE Ellsworth, N Sambuughin, I Puls, A Abel, SQ Lee-Lin, ...
The American Journal of Human Genetics 72 (5), 1293-1299, 2003
5722003
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
H Li, S Wetten, L Li, PLS Jean, R Upmanyu, L Surh, D Hosford, ...
Archives of neurology 65 (1), 45-53, 2008
5392008
A genome-wide investigation of SNPs and CNVs in schizophrenia
AC Need, D Ge, ME Weale, J Maia, S Feng, EL Heinzen, KV Shianna, ...
PLoS Genet 5 (2), e1000373, 2009
5102009
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
SB Prusiner, AL Woerman, DA Mordes, JC Watts, R Rampersaud, ...
Proceedings of the National Academy of Sciences 112 (38), E5308-E5317, 2015
4902015
Age at onset in two common neurodegenerative diseases is genetically controlled
YJ Li, WK Scott, DJ Hedges, F Zhang, PC Gaskell, MA Nance, RL Watts, ...
The American Journal of Human Genetics 70 (4), 985-993, 2002
3512002
Complete genomic screen in Parkinson disease: evidence for multiple genes
WK Scott, MA Nance, RL Watts, JP Hubble, WC Koller, K Lyons, R Pahwa, ...
Jama 286 (18), 2239-2244, 2001
3312001
Transmission of multiple system atrophy prions to transgenic mice
JC Watts, K Giles, A Oehler, L Middleton, DT Dexter, SM Gentleman, ...
Proceedings of the National Academy of Sciences 110 (48), 19555-19560, 2013
3272013
Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections
E Domenici, DR Willé, F Tozzi, I Prokopenko, S Miller, A McKeown, ...
PLoS one 5 (2), e9166, 2010
3232010
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry
LJ Scott, P Muglia, XQ Kong, W Guan, M Flickinger, R Upmanyu, F Tozzi, ...
Proceedings of the National Academy of Sciences 106 (18), 7501-7506, 2009
3152009
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
T Network, C O'Dushlaine, L Rossin, PH Lee, L Duncan, NN Parikshak, ...
Nature neuroscience 18 (2), 199, 2015
2962015
Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts
P Muglia, F Tozzi, NW Galwey, C Francks, R Upmanyu, XQ Kong, ...
Molecular psychiatry 15 (6), 589-601, 2010
2852010
Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease
YJ Li, SA Oliveira, P Xu, ER Martin, JE Stenger, CR Scherzer, MA Hauser, ...
Human molecular genetics 12 (24), 3259-3267, 2003
2642003
Rare deletions at 16p13. 11 predispose to a diverse spectrum of sporadic epilepsy syndromes
EL Heinzen, RA Radtke, TJ Urban, GL Cavalleri, C Depondt, AC Need, ...
The American Journal of Human Genetics 86 (5), 707-718, 2010
2552010
Parkin mutations and susceptibility alleles in late‐onset Parkinson's disease
SA Oliveira, WK Scott, ER Martin, MA Nance, RL Watts, JP Hubble, ...
Annals of Neurology: Official Journal of the American Neurological …, 2003
2492003
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