A comprehensive overview of globally approved JAK inhibitors AM Shawky, FA Almalki, AN Abdalla, AH Abdelazeem, AM Gouda Pharmaceutics 14 (5), 1001, 2022 | 95 | 2022 |
Phytochemical, cytotoxic, and antimicrobial evaluation of the fruits of miswak plant, Salvadora persica L. M Al Bratty, HA Makeen, HA Alhazmi, SM Syame, AN Abdalla, ... Journal of Chemistry 2020, 1-11, 2020 | 72 | 2020 |
Antitumor activity of pyrrolizines and their Cu (II) complexes: Design, synthesis and cytotoxic screening with potential apoptosis-inducing activity AM Gouda, HA El-Ghamry, TM Bawazeer, TA Farghaly, AN Abdalla, ... European journal of medicinal chemistry 145, 350-359, 2018 | 51 | 2018 |
Proapoptotic Activity of Achillea membranacea Essential Oil and Its Major Constituent 1,8-Cineole against A2780 Ovarian Cancer Cells AN Abdalla, U Shaheen, QMA Abdallah, G Flamini, MM Bkhaitan, ... Molecules 25 (7), 1582, 2020 | 50 | 2020 |
Optimization of pyrrolizine-based Schiff bases with 4-thiazolidinone motif: Design, synthesis and investigation of cytotoxicity and anti-inflammatory potency AMG Ahmed M. Shawky, Mohammed A.S. Abourehab, Ashraf N. Abdalla European journal of medicinal chemistry, 2019 | 49* | 2019 |
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2 ASEA Hamad M.Alkahtani, Ashraf N.Abdalla, Ahmad J.Obaidullah, Mohammed M ... Bioorganic chemistry 2019, 2019 | 48* | 2019 |
Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5, 5-diphenylimidazolidine-2, 4-dione derivatives: Molecular docking studies HM Alkahtani, MM Alanazi, FS Aleanizy, FY Alqahtani, A Alhoshani, ... Saudi Pharmaceutical Journal 27 (5), 682-693, 2019 | 42 | 2019 |
Triterpenoidal saponins from the fruits of Gleditsia caspica with proapoptotic properties U Shaheen, EA Ragab, AN Abdalla, A Bader Phytochemistry 145, 168-178, 2018 | 42 | 2018 |
A series of isatin-hydrazones with cytotoxic activity and CDK2 kinase inhibitory activity: a potential type II ATP competitive inhibitor HS Al-Salem, M Arifuzzaman, HM Alkahtani, AN Abdalla, IS Issa, ... Molecules 25 (19), 4400, 2020 | 35 | 2020 |
Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential … AM Shawky, NA Ibrahim, MAS Abourehab, AN Abdalla, AM Gouda Journal of enzyme inhibition and medicinal chemistry 36 (1), 15-33, 2021 | 27 | 2021 |
Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities KM Attalah, AN Abdalla, A Aslam, M Ahmed, MAS Abourehab, NA ElSawy, ... Bioorganic chemistry 94, 103371, 2020 | 27 | 2020 |
One-pot synthesis of novel poly-substituted 3-cyanopyridines: Molecular docking, antimicrobial, cytotoxicity, and DFT/TD-DFT studies IM Abdellah, MR Eletmany, AA Abdelhamid, HS Alghamdi, AN Abdalla, ... Journal of Molecular Structure 1289, 135864, 2023 | 26 | 2023 |
Tamoxifen and the PI3K inhibitor: LY294002 synergistically induce apoptosis and cell cycle arrest in breast cancer MCF-7 cells ME Abdallah, MZ El-Readi, MA Althubiti, RA Almaimani, AM Ismail, S Idris, ... Molecules 25 (15), 3355, 2020 | 25 | 2020 |
Pyrrolizines: design, synthesis, anticancer evaluation and investigation of the potential mechanism of action AM Gouda, AH Abdelazeem, HA Omar, AN Abdalla, MAS Abourehab, ... Bioorganic & Medicinal Chemistry 25 (20), 5637-5651, 2017 | 24 | 2017 |
Synthesis, biological evaluation and molecular docking study of benzimidazole derivatives as α-glucosidase inhibitors and anti-diabetes candidates S Hayat, H Ullah, F Rahim, I Ullah, M Taha, N Iqbal, F Khan, MS Khan, ... Journal of Molecular Structure 1276, 134774, 2023 | 23 | 2023 |
Identification of novel inhibitors for SARS-CoV-2 as therapeutic options using machine learning-based virtual screening, molecular docking and MD simulation A Samad, A Ajmal, A Mahmood, B Khurshid, P Li, SM Jan, AU Rehman, ... Frontiers in Molecular Biosciences 10, 1060076, 2023 | 23 | 2023 |
Discovery of new pyrimidopyrrolizine/indolizine-based derivatives as P-glycoprotein inhibitors: Design, synthesis, cytotoxicity, and MDR reversal activities AM Shawky, AN Abdalla, NA Ibrahim, MAS Abourehab, AM Gouda European Journal of Medicinal Chemistry 218, 113403, 2021 | 22 | 2021 |
Phytochemical Screening and Cytotoxic Properties of Ethanolic Extract of Young and Mature Khat Leaves 6 Rashad Alsanosy,1,2 Hassan A. Alhazmi ,1,3 Shahnaz Sultana,4 Ashraf N ... Journal of chemistry 7897435, 2020 | 21* | 2020 |
Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition WH Malki, AM Gouda, HEA Ali, R Al-Rousan, D Samaha, AN Abdalla, ... European Journal of Medicinal Chemistry 152, 31-52, 2018 | 21 | 2018 |
Reprofiling of full‐length phosphonated carbocyclic 2′‐oxa‐3′‐aza‐nucleosides toward antiproliferative agents: Synthesis, antiproliferative activity, and molecular docking study MM Bkhaitan, AZ Mirza, AN Abdalla, H Shamshad, Z Ul‐Haq, M Alarjah, ... Chemical Biology & Drug Design 90 (5), 679-689, 2017 | 21 | 2017 |