Παρακολούθηση
James DeGregori
James DeGregori
Professor of Biochemistry and Molecular Genetics, University of Colorado SOM
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα ucdenver.edu
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
109882021
Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G1/S-Regulatory Genes
J DeGregori, T Kowalik, JR Nevins
Molecular and cellular biology 15 (8), 4215-4224, 1995
12211995
Distinct roles for E2F proteins in cell growth control and apoptosis
J DeGregori, G Leone, A Miron, L Jakoi, JR Nevins
Proceedings of the National Academy of Sciences 94 (14), 7245-7250, 1997
9081997
Regulation of the cyclin E gene by transcription factor E2F1.
K Ohtani, J Degregori, JR Nevins
Proceedings of the National Academy of Sciences 92 (26), 12146-12150, 1995
8191995
Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
J DeGregori, DG Johnson
Current molecular medicine 6 (7), 739-748, 2006
6362006
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
G Leone, J DeGregori, R Sears, L Jakoi, JR Nevins
Nature 387 (6631), 422-426, 1997
6291997
Ras enhances Myc protein stability
R Sears, G Leone, J DeGregori, JR Nevins
Molecular cell 3 (2), 169-179, 1999
5671999
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.
SN Khleif, J Degregori, CL Yee, GA Otterson, FJ Kaye, JR Nevins, ...
Proceedings of the National Academy of Sciences 93 (9), 4350-4354, 1996
5141996
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
TF Kowalik, J DeGregori, JK Schwarz, JR Nevins
Journal of virology 69 (4), 2491-2500, 1995
5111995
Inhibition of amino acid metabolism selectively targets human leukemia stem cells
CL Jones, BM Stevens, A D'Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ...
Cancer cell 34 (5), 724-740. e4, 2018
4812018
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase
G Leone, J DeGregori, Z Yan, L Jakoi, S Ishida, RS Williams, JR Nevins
Genes & development 12 (14), 2120-2130, 1998
4751998
The genetics of the E2F family of transcription factors: shared functions and unique roles
J DeGregori
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1602 (2), 131-150, 2002
3792002
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease
GU Höglinger, JJ Breunig, C Depboylu, C Rouaux, PP Michel, ...
Proceedings of the National Academy of Sciences 104 (9), 3585-3590, 2007
3262007
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state
EJ Smith, G Leone, J DeGregori, L Jakoi, JR Nevins
Molecular and cellular biology, 1996
3231996
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells
Z Yan, J DeGregori, R Shohet, G Leone, B Stillman, JR Nevins, ...
Proceedings of the National Academy of Sciences 95 (7), 3603-3608, 1998
3221998
Lung adenocarcinoma promotion by air pollutants
W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ...
Nature 616 (7955), 159-167, 2023
3172023
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.
J DeGregori, G Leone, K Ohtani, A Miron, JR Nevins
Genes & development 9 (23), 2873-2887, 1995
2881995
Trisomy 21 consistently activates the interferon response
KD Sullivan, HC Lewis, AA Hill, A Pandey, LP Jackson, JM Cabral, ...
Elife 5, e16220, 2016
2812016
Role of the Rb/E2F pathway in cell growth control
JR Nevins, G Leone, J DeGregori, L Jakoi
Journal of cellular physiology 173 (2), 233-236, 1997
2691997
Cancer as a disease of old age: changing mutational and microenvironmental landscapes
E Laconi, F Marongiu, J DeGregori
British journal of cancer 122 (7), 943-952, 2020
2572020
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