A heme-dependent enzyme forms the nitrogen–nitrogen bond in piperazate YL Du, HY He, MA Higgins, KS Ryan Nature chemical biology 13 (8), 836-838, 2017 | 108 | 2017 |
Two-Enzyme Pathway Links l-Arginine to Nitric Oxide in N-Nitroso Biosynthesis HY He, AC Henderson, YL Du, KS Ryan Journal of the American Chemical Society 141 (9), 4026-4033, 2019 | 64 | 2019 |
Cloning and elucidation of the FR901464 gene cluster revealing a complex acyltransferase-less polyketide synthase using glycerate as starter units F Zhang, HY He, MC Tang, YM Tang, Q Zhou, GL Tang Journal of the American Chemical Society 133 (8), 2452-2462, 2011 | 64 | 2011 |
Ferrocene Redox Controlled Reversible Immobilization of Ruthenium Carbene in Ionic Liquid: A Versatile Catalyst for Ring‐Closing Metathesis G Liu, H He, J Wang Advanced Synthesis & Catalysis 351 (10), 1610-1620, 2009 | 53 | 2009 |
Quartromicin biosynthesis: two alternative polyketide chains produced by one polyketide synthase assembly line HY He, HX Pan, LF Wu, BB Zhang, HB Chai, W Liu, GL Tang Chemistry & biology 19 (10), 1313-1323, 2012 | 51 | 2012 |
Synthetic and biosynthetic routes to nitrogen–nitrogen bonds HY He, H Niikura, YL Du, KS Ryan Chemical Society Reviews, 2022 | 44 | 2022 |
A pyridoxal phosphate–dependent enzyme that oxidizes an unactivated carbon-carbon bond YL Du, R Singh, LM Alkhalaf, E Kuatsjah, HY He, LD Eltis, KS Ryan Nature Chemical Biology 12 (3), 194-199, 2016 | 43 | 2016 |
cis-Double bond formation by thioesterase and transfer by ketosynthase in FR901464 biosynthesis HY He, MC Tang, F Zhang, GL Tang Journal of the American Chemical Society 136 (12), 4488-4491, 2014 | 42 | 2014 |
The Biosynthetic Gene Cluster of Pyrazomycin—AC‐Nucleoside Antibiotic with a Rare Pyrazole Moiety G Zhao, S Yao, KW Rothchild, T Liu, Y Liu, J Lian, HY He, KS Ryan, ... ChemBioChem 21 (5), 644-649, 2020 | 41 | 2020 |
Unconventional origin and hybrid system for construction of pyrrolopyrrole moiety in kosinostatin biosynthesis HM Ma, Q Zhou, YM Tang, Z Zhang, YS Chen, HY He, HX Pan, MC Tang, ... Chemistry & biology 20 (6), 796-805, 2013 | 39 | 2013 |
Biosynthesis of the N–N‐Bond‐Containing Compound l‐Alanosine M Wang, H Niikura, HY He, P Daniel‐Ivad, KS Ryan Angewandte Chemie International Edition 59 (10), 3881-3885, 2020 | 34 | 2020 |
Baeyer–Villiger Oxidation of Acyl Carrier Protein-Tethered Thioester to Acyl Carrier Protein-Linked Thiocarbonate Catalyzed by a Monooxygenase Domain in FR901464 Biosynthesis MC Tang, HY He, F Zhang, GL Tang ACS Catalysis 3 (3), 444-447, 2013 | 30 | 2013 |
Characterization of QmnD3/QmnD4 for Double Bond Formation in Quartromicin Biosynthesis LF Wu, HY He, HX Pan, L Han, R Wang, GL Tang Organic letters 16 (6), 1578-1581, 2014 | 28 | 2014 |
An Unusual Dehydratase Acting on Glycerate and a Ketoreducatse Stereoselectively Reducing á‐Ketone in Polyketide Starter Unit Biosynthesis HY He, H Yuan, MC Tang, GL Tang Angewandte Chemie International Edition 53 (42), 11315-11319, 2014 | 27 | 2014 |
Glycine-derived nitronates bifurcate to O-methylation or denitrification in bacteria HY He, KS Ryan Nature Chemistry 13 (6), 599-606, 2021 | 13 | 2021 |
An engineered biosynthetic–synthetic platform for production of halogenated indolmycin antibiotics ER Hoffarth, S Kong, HY He, KS Ryan Chemical science 12 (25), 8817-8821, 2021 | 1 | 2021 |