| Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance W Huang, A Metlakunta, N Dedousis, P Zhang, I Sipula, JJ Dube, ... diabetes 59 (2), 347-357, 2010 | 599 | 2010 |
| A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication P Wang, JC Alvarez-Perez, DP Felsenfeld, H Liu, S Sivendran, A Bender, ... Nature medicine 21 (4), 383-388, 2015 | 383 | 2015 |
| Glucose infusion in mice: a new model to induce β-cell replication LC Alonso, T Yokoe, P Zhang, DK Scott, SK Kim, CP O'Donnell, ... Diabetes 56 (7), 1792-1801, 2007 | 309 | 2007 |
| Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. CO Quinn, DK Scott, CE Brinckerhoff, LM Matrisian, JJ Jeffrey, ... Journal of Biological Chemistry 265 (36), 22342-22347, 1990 | 261 | 1990 |
| Diabetes mellitus—advances and challenges in human β-cell proliferation P Wang, NM Fiaschi-Taesch, RC Vasavada, DK Scott, A Garcia-Ocana, ... Nature Reviews Endocrinology 11 (4), 201-212, 2015 | 245 | 2015 |
| Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver M Stefanovic-Racic, X Yang, MS Turner, BS Mantell, DB Stolz, ... Diabetes 61 (9), 2330-2339, 2012 | 242 | 2012 |
| Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map E Bernal-Mizrachi, RN Kulkarni, DK Scott, F Mauvais-Jarvis, AF Stewart, ... Diabetes 63 (3), 819-831, 2014 | 203 | 2014 |
| Induction of human β-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6 NM Fiaschi-Taesch, F Salim, J Kleinberger, R Troxell, I Cozar-Castellano, ... Diabetes 59 (8), 1926-1936, 2010 | 175 | 2010 |
| Replication confers β cell immaturity S Puri, N Roy, HA Russ, L Leonhardt, EK French, R Roy, H Bengtsson, ... Nature Communications 9 (1), 485, 2018 | 151 | 2018 |
| Combined inhibition of DYRK1A, SMAD, and trithorax pathways synergizes to induce robust replication in adult human beta cells P Wang, E Karakose, H Liu, E Swartz, C Ackeifi, V Zlatanic, J Wilson, ... Cell metabolism 29 (3), 638-652. e5, 2019 | 144 | 2019 |
| The repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolism DK Scott, RM O'Doherty, JM Stafford, CB Newgard, DK Granner Journal of Biological Chemistry 273 (37), 24145-24151, 1998 | 139 | 1998 |
| ChREBP mediates glucose-stimulated pancreatic β-cell proliferation MR Metukuri, P Zhang, MK Basantani, C Chin, RE Stamateris, LC Alonso, ... Diabetes 61 (8), 2004-2015, 2012 | 123 | 2012 |
| Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids LE Shipp, JV Lee, CY Yu, M Pufall, P Zhang, DK Scott, JC Wang PloS one 5 (10), e13754, 2010 | 122 | 2010 |
| Parathyroid hormone induces c-fos and c-jun messenger RNA in rat osteoblastic cells. JC Clohisy, DK Scott, KD Brakenhoff, CO Quinn, NC Partridge Molecular endocrinology 6 (11), 1834-1842, 1992 | 116 | 1992 |
| c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate LR Edmunds, L Sharma, A Kang, J Lu, J Vockley, S Basu, R Uppala, ... Journal of Biological Chemistry 289 (36), 25382-25392, 2014 | 112 | 2014 |
| CCAAT/enhancer-binding protein β is an accessory factor for the glucocorticoid response from the cAMP response element in the rat phosphoenolpyruvate carboxykinase gene promoter K Yamada, DT Duong, DK Scott, JC Wang, DK Granner Journal of Biological Chemistry 274 (9), 5880-5887, 1999 | 112 | 1999 |
| Prolonged culture in low glucose induces apoptosis of rat pancreatic β-cells through induction of c-myc M Van de Casteele, BA Kefas, Y Cai, H Heimberg, DK Scott, JC Henquin, ... Biochemical and biophysical research communications 312 (4), 937-944, 2003 | 109 | 2003 |
| Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex RK Hall, DK Scott, EL Noisin, PC Lucas, DK Granner Molecular and cellular biology 12 (12), 5527-5535, 1992 | 107 | 1992 |
| GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration C Ackeifi, P Wang, E Karakose, JE Manning Fox, BJ González, H Liu, ... Science translational medicine 12 (530), eaaw9996, 2020 | 104 | 2020 |
| Further characterization of the glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. The role of the glucocorticoid receptor-binding sites DK Scott, PE Strömstedt, JC Wang, DK Granner Molecular Endocrinology 12 (4), 482-491, 1998 | 103 | 1998 |
