| Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers VS Mandala, MJ McKay, AA Shcherbakov, AJ Dregni, A Kolocouris, ... Nature structural & molecular biology 27 (12), 1202-1208, 2020 | 370 | 2020 |
| Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L MD Sacco, C Ma, P Lagarias, A Gao, JA Townsend, X Meng, P Dube, ... Science Advances 6 (50), eabe0751, 2020 | 337 | 2020 |
| Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are nonspecific promiscuous SARS-CoV-2 main protease inhibitors C Ma, Y Hu, JA Townsend, PI Lagarias, MT Marty, A Kolocouris, J Wang ACS pharmacology & translational science 3 (6), 1265-1277, 2020 | 218 | 2020 |
| Membrane protein structure, function, and dynamics: a perspective from experiments and theory Z Cournia, TW Allen, I Andricioaei, B Antonny, D Baum, G Brannigan, ... The Journal of membrane biology 248, 611-640, 2015 | 218 | 2015 |
| Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2 N Kolocouris, A Kolocouris, GB Foscolos, G Fytas, J Neyts, E Padalko, ... Journal of medicinal chemistry 39 (17), 3307-3318, 1996 | 212 | 1996 |
| Spiro [pyrrolidine-2, 2′-adamantanes]: synthesis, anti-influenza virus activity and conformational properties I Stylianakis, A Kolocouris, N Kolocouris, G Fytas, GB Foscolos, E Padalko, ... Bioorganic & medicinal chemistry letters 13 (10), 1699-1703, 2003 | 177 | 2003 |
| Synthesis and antiviral activity evaluation of some aminoadamantane derivatives N Kolocouris, GB Foscolos, A Kolocouris, P Marakos, N Pouli, G Fytas, ... Journal of medicinal chemistry 37 (18), 2896-2902, 1994 | 166 | 1994 |
| An effort to understand the molecular basis of hypertension through the study of conformational analysis of losartan and sarmesin using a combination of nuclear magnetic … T Mavromoustakos, A Kolocouris, M Zervou, P Roumelioti, J Matsoukas, ... Journal of medicinal chemistry 42 (10), 1714-1722, 1999 | 156 | 1999 |
| Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and a FlipGFP-based reporter assay C Ma, MD Sacco, Z Xia, G Lambrinidis, JA Townsend, Y Hu, X Meng, ... ACS central science 7 (7), 1245-1260, 2021 | 124 | 2021 |
| Inhibitors of the M2 proton channel engage and disrupt transmembrane networks of hydrogen-bonded waters JL Thomaston, NF Polizzi, A Konstantinidi, J Wang, A Kolocouris, ... Journal of the American Chemical Society 140 (45), 15219-15226, 2018 | 108 | 2018 |
| New 2-(1-adamantylcarbonyl) pyridine and 1-acetyladamantane thiosemicarbazones–thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation A Kolocouris, K Dimas, C Pannecouque, M Witvrouw, GB Foscolos, ... Bioorganic & Medicinal Chemistry Letters 12 (5), 723-727, 2002 | 79 | 2002 |
| A novel analytical method to detect adulteration of virgin olive oil by other oils T Mavromoustakos, M Zervou, G Bonas, A Kolocouris, P Petrakis Journal of the American Oil Chemists' Society 77 (4), 405-411, 2000 | 79 | 2000 |
| Novel 3-(2-adamantyl) pyrrolidines with potent activity against influenza A virus—identification of aminoadamantane derivatives bearing two pharmacophoric amine groups G Stamatiou, A Kolocouris, N Kolocouris, G Fytas, GB Foscolos, J Neyts, ... Bioorganic & medicinal chemistry letters 11 (16), 2137-2142, 2001 | 77 | 2001 |
| Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A A Kolocouris, C Tzitzoglaki, FB Johnson, R Zell, AK Wright, TA Cross, ... Journal of medicinal chemistry 57 (11), 4629-4639, 2014 | 76 | 2014 |
| Heterocyclic rimantadine analogues with antiviral activity G Stamatiou, GB Foscolos, G Fytas, A Kolocouris, N Kolocouris, ... Bioorganic & medicinal chemistry 11 (24), 5485-5492, 2003 | 72 | 2003 |
| Biological activity of myricetin and its derivatives against human leukemic cell lines in vitro K Dimas, C Demetzos, D Angelopoulou, A Kolokouris, T Mavromoustakos Pharmacological Research 42 (5), 475-478, 2000 | 54 | 2000 |
| Influence of an additional 2-amino substituent of the 1-aminoethyl pharmacophore group on the potency of rimantadine against influenza virus A D Tataridis, G Fytas, A Kolocouris, C Fytas, N Kolocouris, GB Foscolos, ... Bioorganic & medicinal chemistry letters 17 (3), 692-696, 2007 | 53 | 2007 |
| The design and synthesis of a potent angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone angiotensin II JM Matsoukas, L Polevaya, J Ancans, T Mavromoustakos, A Kolocouris, ... Bioorganic & medicinal chemistry 8 (1), 1-10, 2000 | 53 | 2000 |
| Free energy calculations reveal the origin of binding preference for aminoadamantane blockers of influenza A/M2TM pore P Gkeka, S Eleftheratos, A Kolocouris, Z Cournia Journal of Chemical Theory and Computation 9 (2), 1272-1281, 2013 | 52 | 2013 |
| Are the 2-isomers of the drug rimantadine active anti-influenza A agents? G Zoidis, N Kolocouris, GB Foscolos, A Kolocouris, G Fytas, P Karayannis, ... Antiviral Chemistry and Chemotherapy 14 (3), 153-164, 2003 | 51 | 2003 |
