Aoife McLysaght

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Takashi MakinoProfessor, Tohoku UniversityVerified email at tohoku.ac.jp
Kenneth H. WolfeProfessor of Genomic Evolution, University College DublinVerified email at ucd.ie
Nikolaos VakirlisJunior Investigator, Group Leader at BSRC "Alexander Fleming", GreeceVerified email at fleming.gr
Karsten HokampBioinformatics Research Officer, Smurfit Institute of Genetics, Trinity College DublinVerified email at tcd.ie
Anne-Ruxandra CarvunisUniversity of PittsburghVerified email at pitt.edu
Laurence D HurstUniversity of BathVerified email at bath.ac.uk
Alan M. RiceUniversity of BathVerified email at bath.ac.uk
Brandon GautDistinguished Professor of Ecology and Evolutionary Biology, UC IrvineVerified email at uci.edu
Pierre BaldiProfessor, University of California, IrvineVerified email at ics.uci.edu
Gianluca PollastriAssociate Professor, University College DublinVerified email at ucd.ie
Anthony K. RedmondResearch Fellow, Trinity College DublinVerified email at tcd.ie
Yoichiro NakataniOsaka UniversityVerified email at cgi.med.osaka-u.ac.jp
Åsa Pérez-BercoffUniversity of New South WalesVerified email at unsw.edu.au
Gabriel MaraisCIBIO, BIOPOLIS/Univ. PortoVerified email at cibio.up.pt
Stefan RothenburgUC DavisVerified email at ucdavis.edu
Anton EnrightGroup Leader, Department of Pathology, University of CambridgeVerified email at cam.ac.uk
Kevin MitchellAssociate Professor of Genetics and Neuroscience, Trinity College DublinVerified email at tcd.ie
David SankoffUniversity of OttawaVerified email at uottawa.ca
Cathal SeoigheUniversity of GalwayVerified email at universityofgalway.ie

Aoife McLysaght

Chair of Evolutionary Genetics, Trinity College Dublin

Verified email at tcd.ie - Homepage

Molecular Evolution Comparative Genomics


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Initial sequencing and analysis of the human genome US DOE Joint Genome Institute: Hawkins Trevor 4 Branscomb Elbert 4 Predki ... nature 409 (6822), 860-921, 2001	29702	2001
Extensive genomic duplication during early chordate evolution A McLysaght, K Hokamp, KH Wolfe Nature genetics 31 (2), 200-204, 2002	627	2002
Porter: a new, accurate server for protein secondary structure prediction G Pollastri, A McLysaght Bioinformatics 21 (8), 1719-1720, 2005	578	2005
Recent de novo origin of human protein-coding genes DG Knowles, A McLysaght Genome research 19 (10), 1752-1759, 2009	319	2009
Ohnologs in the human genome are dosage balanced and frequently associated with disease T Makino, A McLysaght Proceedings of the National Academy of Sciences 107 (20), 9270, 2010	270	2010
Extensive gene gain associated with adaptive evolution of poxviruses A McLysaght, PF Baldi, BS Gaut Proceedings of the National Academy of Sciences 100 (26), 15655-15660, 2003	222	2003
Mammalian X chromosome inactivation evolved as a dosage-compensation mechanism for dosage-sensitive genes on the X chromosome E Pessia, T Makino, M Bailly-Bechet, A McLysaght, GAB Marais Proceedings of the National Academy of Sciences 109 (14), 5346-5351, 2012	191	2012
Open questions in the study of de novo genes: what, how and why A McLysaght, LD Hurst Nature Reviews Genetics 17 (9), 567-578, 2016	185	2016
New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation A McLysaght, D Guerzoni Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015	157	2015
Dosage sensitivity is a major determinant of human copy number variant pathogenicity AM Rice, A McLysaght Nature communications 8 (1), 14366, 2017	123	2017
A survey of host range genes in poxvirus genomes KA Bratke, A McLysaght, S Rothenburg Infection, Genetics and Evolution 14, 406-425, 2013	123	2013
The complex relationship of gene duplication and essentiality T Makino, K Hokamp, A McLysaght Trends in genetics 25 (4), 152-155, 2009	115	2009
A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ... Molecular cell 70 (3), 408-421. e8, 2018	110	2018
Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human A McLysaght, AJ Enright, L Skrabanek, KH Wolfe Yeast 1 (1), 22-36, 2000	100	2000
The 2R hypothesis and the human genome sequence K Hokamp, A McLysaght, KH Wolfe Journal of structural and functional genomics 3, 95-110, 2003	97	2003
Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes N Vakirlis, AR Carvunis, A McLysaght Elife 9, e53500, 2020	91	2020
Dosage-sensitive genes in evolution and disease AM Rice, A McLysaght BMC biology 15 (1), 1-10, 2017	91	2017
Identification of multiple independent horizontal gene transfers into poxviruses using a comparative genomics approach KA Bratke, A McLysaght BMC evolutionary biology 8 (1), 1-13, 2008	80	2008
LineUp: statistical detection of chromosomal homology with application to plant comparative genomics S Hampson, A McLysaght, B Gaut, P Baldi Genome research 13 (5), 999-1010, 2003	77	2003
De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences N Vakirlis, O Acar, B Hsu, N Castilho Coelho, SB Van Oss, A Wacholder, ... Nature communications 11 (1), 781, 2020	76	2020

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