Aoife McLysaght
Aoife McLysaght
Chair of Evolutionary Genetics, Trinity College Dublin
Verified email at - Homepage
Cited by
Cited by
Initial sequencing and analysis of the human genome
US DOE Joint Genome Institute: Hawkins Trevor 4 Branscomb Elbert 4 Predki ...
nature 409 (6822), 860-921, 2001
Extensive genomic duplication during early chordate evolution
A McLysaght, K Hokamp, KH Wolfe
Nature genetics 31 (2), 200-204, 2002
Porter: a new, accurate server for protein secondary structure prediction
G Pollastri, A McLysaght
Bioinformatics 21 (8), 1719-1720, 2005
Recent de novo origin of human protein-coding genes
DG Knowles, A McLysaght
Genome research 19 (10), 1752-1759, 2009
Ohnologs in the human genome are dosage balanced and frequently associated with disease
T Makino, A McLysaght
Proceedings of the National Academy of Sciences 107 (20), 9270, 2010
Extensive gene gain associated with adaptive evolution of poxviruses
A McLysaght, PF Baldi, BS Gaut
Proceedings of the National Academy of Sciences 100 (26), 15655-15660, 2003
Mammalian X chromosome inactivation evolved as a dosage-compensation mechanism for dosage-sensitive genes on the X chromosome
E Pessia, T Makino, M Bailly-Bechet, A McLysaght, GAB Marais
Proceedings of the National Academy of Sciences 109 (14), 5346-5351, 2012
Open questions in the study of de novo genes: what, how and why
A McLysaght, LD Hurst
Nature Reviews Genetics 17 (9), 567-578, 2016
New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation
A McLysaght, D Guerzoni
Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015
Dosage sensitivity is a major determinant of human copy number variant pathogenicity
AM Rice, A McLysaght
Nature communications 8 (1), 14366, 2017
A survey of host range genes in poxvirus genomes
KA Bratke, A McLysaght, S Rothenburg
Infection, Genetics and Evolution 14, 406-425, 2013
The complex relationship of gene duplication and essentiality
T Makino, K Hokamp, A McLysaght
Trends in genetics 25 (4), 152-155, 2009
A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities
E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ...
Molecular cell 70 (3), 408-421. e8, 2018
Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human
A McLysaght, AJ Enright, L Skrabanek, KH Wolfe
Yeast 1 (1), 22-36, 2000
The 2R hypothesis and the human genome sequence
K Hokamp, A McLysaght, KH Wolfe
Journal of structural and functional genomics 3, 95-110, 2003
Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes
N Vakirlis, AR Carvunis, A McLysaght
Elife 9, e53500, 2020
Dosage-sensitive genes in evolution and disease
AM Rice, A McLysaght
BMC biology 15 (1), 1-10, 2017
Identification of multiple independent horizontal gene transfers into poxviruses using a comparative genomics approach
KA Bratke, A McLysaght
BMC evolutionary biology 8 (1), 1-13, 2008
LineUp: statistical detection of chromosomal homology with application to plant comparative genomics
S Hampson, A McLysaght, B Gaut, P Baldi
Genome research 13 (5), 999-1010, 2003
De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
N Vakirlis, O Acar, B Hsu, N Castilho Coelho, SB Van Oss, A Wacholder, ...
Nature communications 11 (1), 781, 2020
The system can't perform the operation now. Try again later.
Articles 1–20