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Shengjia Wu
Shengjia Wu
Verified email at buffalo.edu
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Cited by
Year
A translational platform PBPK model for antibody disposition in the brain
HY Chang, S Wu, G Meno-Tetang, DK Shah
Journal of pharmacokinetics and pharmacodynamics 46, 319-338, 2019
542019
Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models
EA Chowdhury, G Meno-Tetang, HY Chang, S Wu, HW Huang, T Jamier, ...
Advanced Drug Delivery Reviews 170, 214-237, 2021
482021
Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis
HY Chang, S Wu, Y Li, W Zhang, M Burrell, CI Webster, DK Shah
MAbs 13 (1), 1874121, 2021
262021
Determination of ADC cytotoxicity in immortalized human cell lines
S Wu, DK Shah
Antibody-Drug Conjugates: Methods and Protocols, 329-340, 2020
102020
Effect of the size of protein therapeutics on brain pharmacokinetics following systematic administration
HY Chang, S Wu, Y Li, L Guo, Y Li, DK Shah
The AAPS journal 24 (3), 62, 2022
92022
Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central …
HY Chang, S Wu, EA Chowdhury, DK Shah
Journal of Pharmacokinetics and Pharmacodynamics 49 (3), 337-362, 2022
82022
Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes
J Chandran, EA Chowdhury, M Perkinton, T Jamier, D Sutton, S Wu, ...
Gene Therapy 30 (1), 132-141, 2023
42023
PBPK model for antibody disposition in mouse brain: validation using large-pore microdialysis data
S Wu, F Le Prieult, CJ Phipps, M Mezler, DK Shah
Journal of Pharmacokinetics and Pharmacodynamics 49 (6), 579-592, 2022
42022
Algorithmic multiscale analysis for the FcRn mediated regulation of antibody PK in human
DG Patsatzis, S Wu, DK Shah, DA Goussis
Scientific Reports 12 (1), 6208, 2022
22022
Pharmacokinetics of AAV9 Mediated Trastuzumab Expression in Rat Brain Following Systemic and Local Administration
EA Chowdhury, M Ahuja, S Wu, S Liu, HW Huang, M Kumar, KS Sunkara, ...
Journal of Pharmaceutical Sciences 113 (1), 131-140, 2024
12024
Investigation of Antibody Pharmacokinetics in the Brain Following Intra-CNS Administration and Development of PBPK Model to Characterize the Data
S Wu, HY Chang, EA Chowdhury, HW Huang, DK Shah
The AAPS Journal 26 (2), 29, 2024
2024
Expansion of platform physiologically-based pharmacokinetic model for monoclonal antibodies towards different preclinical species: cats, sheep, and dogs
HW Huang, S Wu, EA Chowdhury, DK Shah
Journal of Pharmacokinetics and Pharmacodynamics, 1-18, 2023
2023
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