Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system MJ Workman, MM Mahe, S Trisno, HM Poling, CL Watson, N Sundaram, ... Nature medicine 23 (1), 49-59, 2017 | 574 | 2017 |
Human iPSC-derived blood-brain barrier chips enable disease modeling and personalized medicine applications GD Vatine, R Barrile, MJ Workman, S Sances, BK Barriga, M Rahnama, ... Cell stem cell 24 (6), 995-1005. e6, 2019 | 453 | 2019 |
Enhanced utilization of induced pluripotent stem cell–derived human intestinal organoids using microengineered chips MJ Workman, JP Gleeson, EJ Troisi, HQ Estrada, SJ Kerns, CD Hinojosa, ... Cellular and molecular gastroenterology and hepatology 5 (4), 669-677. e2, 2018 | 212 | 2018 |
Multi-lineage human iPSC-derived platforms for disease modeling and drug discovery A Sharma, S Sances, MJ Workman, CN Svendsen Cell stem cell 26 (3), 309-329, 2020 | 206 | 2020 |
Growth hormone is permissive for neoplastic colon growth V Chesnokova, S Zonis, C Zhou, MV Recouvreux, A Ben-Shlomo, T Araki, ... Proceedings of the National Academy of Sciences 113 (23), E3250-E3259, 2016 | 100 | 2016 |
Recent advances in human iPSC-derived models of the blood–brain barrier MJ Workman, CN Svendsen Fluids and Barriers of the CNS 17, 1-10, 2020 | 82 | 2020 |
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines EG Baxi, T Thompson, J Li, JA Kaye, RG Lim, J Wu, D Ramamoorthy, ... Nature neuroscience 25 (2), 226-237, 2022 | 79 | 2022 |
Cross-comparison of human iPSC motor neuron models of familial and sporadic ALS reveals early and convergent transcriptomic disease signatures R Ho, MJ Workman, P Mathkar, K Wu, KJ Kim, JG O’Rourke, M Kellogg, ... Cell systems 12 (2), 159-175. e9, 2021 | 38 | 2021 |
OTX2 and CRX rescue overlapping and photoreceptor‐specific functions in the Drosophila eye D Terrell, B Xie, M Workman, S Mahato, A Zelhof, B Gebelein, T Cook Developmental Dynamics 241 (1), 215-228, 2012 | 29 | 2012 |
Separable transcriptional regulatory domains within Otd control photoreceptor terminal differentiation events EC McDonald, B Xie, M Workman, M Charlton-Perkins, DA Terrell, ... Developmental biology 347 (1), 122-132, 2010 | 28 | 2010 |
Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis N Yucer, R Ahdoot, MJ Workman, AH Laperle, MS Recouvreux, ... Cell reports 37 (13), 2021 | 24 | 2021 |
Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects MJ Workman, RG Lim, J Wu, A Frank, L Ornelas, L Panther, E Galvez, ... Neuron 111 (8), 1191-1204. e5, 2023 | 23 | 2023 |
Generation of a human iPSC-based blood-brain barrier chip S Jagadeesan, MJ Workman, A Herland, CN Svendsen, GD Vatine JoVE (Journal of Visualized Experiments), e60925, 2020 | 22 | 2020 |
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data D Ramamoorthy, K Severson, S Ghosh, K Sachs, JD Glass, CN Fournier, ... Nature Computational Science 2 (9), 605-616, 2022 | 15 | 2022 |
Modeling intestinal epithelial response to interferon-γ in induced pluripotent stem cell-derived human intestinal organoids MJ Workman, E Troisi, SR Targan, CN Svendsen, RJ Barrett International journal of molecular sciences 22 (1), 288, 2020 | 14 | 2020 |
Identification of prophagein Hawaiian coastal water isolate of Staphylococcus Aureus M Workman, OD Nigro, GF Steward Journal of Young Investigators, 2006 | 14 | 2006 |
Systems and methods for growth of intestinal cells in microfluidic devices SJ Kerns, N Wen, C Lucchesi, CD Hinojosa, J Fraser, J Puerta, ... US Patent 11,326,149, 2022 | 10 | 2022 |
In vivo model of human small intestine using pluripotent stem cells and methods of making and using same JM Wells, CL Watson, JO Munera, MM Mahe, MA Helmrath, MJ Workman US Patent App. 15/515,840, 2017 | 10 | 2017 |
Single-cell RNA-seq analysis of human iPSC-derived motor neurons resolves early and predictive ALS signatures R Ho, MJ Workman, P Mathkar, K Wu, KJ Kim, JG O’Rourke, M Kellogg, ... BioRxiv, 2020.04. 27.064584, 2020 | 9 | 2020 |
Microglial transcription profiles in mouse and human are driven by APOE4 and sex VA Moser, MJ Workman, SJ Hurwitz, RM Lipman, CJ Pike, CN Svendsen Iscience 24 (11), 2021 | 7 | 2021 |