pH-Metric logP 10. Determination of liposomal membrane-water partition coefficients of lonizable drugs A Avdeef, KJ Box, JEA Comer, C Hibbert, KY Tam Pharmaceutical research 15, 209-215, 1998 | 539 | 1998 |
PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent–water mixtures A Avdeef, KJ Box, JEA Comer, M Gilges, M Hadley, C Hibbert, ... Journal of pharmaceutical and biomedical analysis 20 (4), 631-641, 1999 | 313 | 1999 |
Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein … KM Foote, K Blades, A Cronin, S Fillery, SS Guichard, L Hassall, I Hickson, ... Journal of medicinal chemistry 56 (5), 2125-2138, 2013 | 244 | 2013 |
Multi-wavelength spectrophotometric determination of acid dissociation constants: a validation study KY Tam, K Takács-Novák Analytica chimica acta 434 (1), 157-167, 2001 | 219 | 2001 |
Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs RI Allen, KJ Box, JEA Comer, C Peake, KY Tam Journal of pharmaceutical and biomedical analysis 17 (4-5), 699-712, 1998 | 210 | 1998 |
Pathological mechanisms and therapeutic strategies for Alzheimer¢s disease Y Ju, KY Tam Neural Regeneration Research 17 (3), 543-549, 2022 | 192 | 2022 |
Calculation of Abraham descriptors from solvent–water partition coefficients in four different systems; evaluation of different methods of calculation AM Zissimos, MH Abraham, MC Barker, KJ Box, KY Tam Journal of the Chemical Society, Perkin Transactions 2, 470-477, 2002 | 170 | 2002 |
Targeting tumor metabolism for cancer treatment: is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target? W Zhang, SL Zhang, X Hu, KY Tam International journal of biological sciences 11 (12), 1390, 2015 | 165 | 2015 |
Silica-encapsulated nanomagnetic particle as a new recoverable biocatalyst carrier SC Tsang, CH Yu, X Gao, K Tam The Journal of Physical Chemistry B 110 (34), 16914-16922, 2006 | 158 | 2006 |
Colloidal stable silica encapsulated nano-magnetic composite as a novel bio-catalyst carrier X Gao, KMK Yu, KY Tam, SC Tsang Chemical Communications, 2998-2999, 2003 | 150 | 2003 |
Lipophilicity profiles: theory and measurement J Comer, K Tam Pharmacokinetic optimization in drug research: Biological, physicochemical …, 2001 | 141 | 2001 |
Immobilization of BSA on silica-coated magnetic iron oxide nanoparticle CH Yu, A Al-Saadi, SJ Shih, L Qiu, KY Tam, SC Tsang The Journal of Physical Chemistry C 113 (2), 537-543, 2009 | 137 | 2009 |
Study of Catalytic Sites on Ruthenium For Hydrogenation of N-ethylcarbazole: Implications of Hydrogen Storage via Reversible Catalytic Hydrogenation K Morawa Eblagon, K Tam, KMK Yu, SL Zhao, XQ Gong, H He, L Ye, ... The Journal of Physical Chemistry C 114 (21), 9720-9730, 2010 | 123 | 2010 |
Calculation of Abraham descriptors from experimental data from seven HPLC systems; evaluation of five different methods of calculation AM Zissimos, MH Abraham, CM Du, K Valko, C Bevan, D Reynolds, ... Journal of the Chemical Society, Perkin Transactions 2, 2001-2010, 2002 | 123 | 2002 |
Comparison of catalytic performance of supported ruthenium and rhodium for hydrogenation of 9-ethylcarbazole for hydrogen storage applications KM Eblagon, K Tam, SCE Tsang Energy & Environmental Science 5 (9), 8621-8630, 2012 | 114 | 2012 |
How well can the Caco-2/Madin− Darby canine kidney models predict effective human Jejunal permeability? A Avdeef, KY Tam Journal of medicinal chemistry 53 (9), 3566-3584, 2010 | 113 | 2010 |
Multiwavelength spectrophotometric determination of acid dissociation constants: Part V: microconstants and tautomeric ratios of diprotic amphoteric drugs K Takács-Novák, KY Tam Journal of pharmaceutical and biomedical analysis 21 (6), 1171-1182, 2000 | 110 | 2000 |
Linagliptin, a dipeptidyl peptidase-4 inhibitor, mitigates cognitive deficits and pathology in the 3xTg-AD mouse model of Alzheimer¢s disease J Kosaraju, RMD Holsinger, L Guo, KY Tam Molecular Neurobiology 54, 6074-6084, 2017 | 103 | 2017 |
A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions D Buttar, N Colclough, S Gerhardt, PA MacFaul, SD Phillips, A Plowright, ... Bioorganic & medicinal chemistry 18 (21), 7486-7496, 2010 | 102 | 2010 |
Comparative study of catalytic hydrogenation of 9-ethylcarbazole for hydrogen storage over noble metal surfaces KM Eblagon, K Tam, KMK Yu, SCE Tsang The Journal of Physical Chemistry C 116 (13), 7421-7429, 2012 | 98 | 2012 |