Structures of complement component C3 provide insights into the function and evolution of immunity BJC Janssen, EG Huizinga, HCA Raaijmakers, A Roos, MR Daha, ... Nature 437 (7058), 505-511, 2005 | 627 | 2005 |
Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome V Frémeaux-Bacchi, EC Miller, MK Liszewski, L Strain, J Blouin, AL Brown, ... Blood, The Journal of the American Society of Hematology 112 (13), 4948-4952, 2008 | 468 | 2008 |
Structure of C3b reveals conformational changes that underlie complement activity BJC Janssen, A Christodoulidou, A McCarthy, JD Lambris, P Gros Nature 444 (7116), 213-216, 2006 | 431 | 2006 |
Structure of complement fragment C3b–factor H and implications for host protection by complement regulators J Wu, YQ Wu, D Ricklin, BJC Janssen, JD Lambris, P Gros Nature immunology 10 (7), 728-733, 2009 | 396 | 2009 |
Complement driven by conformational changes P Gros, FJ Milder, BJC Janssen Nature Reviews Immunology 8 (1), 48-58, 2008 | 391 | 2008 |
Structural basis of semaphorin–plexin signalling BJC Janssen, RA Robinson, F Pérez-Brangulí, CH Bell, KJ Mitchell, ... Nature 467 (7319), 1118-1122, 2010 | 270 | 2010 |
Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor SHM Rooijakkers, J Wu, M Ruyken, R Van Domselaar, KL Planken, ... Nature immunology 10 (7), 721, 2009 | 262 | 2009 |
Influence of donor C3 allotype on late renal-transplantation outcome KM Brown, E Kondeatis, RW Vaughan, SP Kon, CKT Farmer, JD Taylor, ... New England Journal of Medicine 354 (19), 2014-2023, 2006 | 203 | 2006 |
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex BJC Janssen, T Malinauskas, GA Weir, MZ Cader, C Siebold, EY Jones Nature structural & molecular biology 19 (12), 1293-1299, 2012 | 202 | 2012 |
Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition BJC Janssen, EF Halff, JD Lambris, P Gros Journal of Biological Chemistry 282 (40), 29241-29247, 2007 | 147 | 2007 |
Factor B structure provides insights into activation of the central protease of the complement system FJ Milder, L Gomes, A Schouten, BJC Janssen, EG Huizinga, RA Romijn, ... Nature structural & molecular biology 14 (3), 224-228, 2007 | 133 | 2007 |
Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds BJC Janssen, HJ Schirra, FT Lay, MA Anderson, DJ Craik Biochemistry 42 (27), 8214-8222, 2003 | 130 | 2003 |
Structural basis of myelin-associated glycoprotein adhesion and signalling MF Pronker, S Lemstra, J Snijder, AJR Heck, DME Thies-Weesie, ... Nature communications 7 (1), 13584, 2016 | 119 | 2016 |
Structural basis for plexin activation and regulation Y Kong, BJC Janssen, T Malinauskas, VR Vangoor, CH Coles, ... Neuron 91 (3), 548-560, 2016 | 106 | 2016 |
Structural insights into the central complement component C3 BJC Janssen, P Gros Molecular immunology 44 (1-3), 3-10, 2007 | 98 | 2007 |
Insights into complement convertase formation based on the structure of the factor B‐cobra venom factor complex BJC Janssen, L Gomes, RI Koning, DI Svergun, AJ Koster, DC Fritzinger, ... The EMBO journal 28 (16), 2469-2478, 2009 | 84 | 2009 |
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction VA Jackson, DH Meijer, M Carrasquero, LS van Bezouwen, ED Lowe, ... Nature communications 9 (1), 1079, 2018 | 67 | 2018 |
Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release N Leloup, P Lössl, DH Meijer, M Brennich, AJR Heck, DME Thies-Weesie, ... Nature Communications 8 (1), 1708, 2017 | 46 | 2017 |
Crystallographic evidence for deviating C3b structure BJC Janssen, RJ Read, AT Brünger, P Gros Nature 448 (7154), E1-E2, 2007 | 45 | 2007 |
Functional characterization of human C3/cobra venom factor hybrid proteins for therapeutic complement depletion DC Fritzinger, BE Hew, M Thorne, MK Pangburn, BJC Janssen, P Gros, ... Developmental & Comparative Immunology 33 (1), 105-116, 2009 | 38 | 2009 |