| Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment L Zhong, L Yao, RJ Tower, Y Wei, Z Miao, J Park, R Shrestha, L Wang, ... elife 9, e54695, 2020 | 257 | 2020 |
| Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss W Yu, L Zhong, L Yao, Y Wei, T Gui, Z Li, H Kim, N Holdreith, X Jiang, ... The Journal of clinical investigation 131 (2), 2021 | 156 | 2021 |
| The regulatory role of signaling crosstalk in hypertrophy of MSCs and human articular chondrocytes L Zhong, X Huang, M Karperien, JN Post International journal of molecular sciences 16 (8), 19225-19247, 2015 | 145 | 2015 |
| Targeting cartilage EGFR pathway for osteoarthritis treatment Y Wei, L Luo, T Gui, F Yu, L Yan, L Yao, L Zhong, W Yu, B Han, JM Patel, ... Science translational medicine 13 (576), eabb3946, 2021 | 120 | 2021 |
| Correlation between gene expression and osteoarthritis progression in human L Zhong, X Huang, M Karperien, JN Post International journal of molecular sciences 17 (7), 1126, 2016 | 120 | 2016 |
| T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling B Ma, L Zhong, CA van Blitterswijk, JN Post, M Karperien Journal of Biological Chemistry 288 (24), 17552-17558, 2013 | 74 | 2013 |
| Superoxide dismutase-loaded porous polymersomes as highly efficient antioxidant nanoparticles targeting synovium for osteoarthritis therapy T Gui, L Luo, B Chhay, L Zhong, Y Wei, L Yao, W Yu, J Li, CL Nelson, ... Biomaterials 283, 121437, 2022 | 64 | 2022 |
| The effects of the WNT-signaling modulators BIO and PKF118-310 on the chondrogenic differentiation of human mesenchymal stem cells X Huang, L Zhong, J Hendriks, JN Post, M Karperien International journal of molecular sciences 19 (2), 561, 2018 | 46 | 2018 |
| Endogenous DKK1 and FRZB regulate chondrogenesis and hypertrophy in three-dimensional cultures of human chondrocytes and human mesenchymal stem cells L Zhong, X Huang, ED Rodrigues, JCH Leijten, T Verrips, M El Khattabi, ... Stem cells and development 25 (23), 1808-1817, 2016 | 42 | 2016 |
| Nitric oxide mediates crosstalk between interleukin 1β and WNT signaling in primary human chondrocytes by reducing DKK1 and FRZB expression L Zhong, S Schivo, X Huang, J Leijten, M Karperien, JN Post International journal of molecular sciences 18 (11), 2491, 2017 | 38 | 2017 |
| Periarticular mesenchymal progenitors initiate and contribute to secondary ossification center formation during mouse long bone development W Tong, RJ Tower, C Chen, L Wang, L Zhong, Y Wei, H Sun, G Cao, H Jia, ... Stem Cells 37 (5), 677-689, 2019 | 34 | 2019 |
| Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis A Chandra, L Wang, T Young, L Zhong, WJ Tseng, MA Levine, K Cengel, ... The FASEB Journal 32 (1), 52, 2018 | 34 | 2018 |
| Promoted chondrogenesis of cocultured chondrocytes and mesenchymal stem cells under hypoxia using in-situ forming degradable hydrogel scaffolds X Huang, Y Hou, LL Zhong, D Huang, H Qian, M Karperien, W Chen Biomacromolecules 19 (1), 94-102, 2018 | 29 | 2018 |
| Gli1 defines a subset of fibro‐adipogenic progenitors that promote skeletal muscle regeneration with less fat accumulation L Yao, ED Tichy, L Zhong, S Mohanty, L Wang, E Ai, S Yang, F Mourkioti, ... Journal of Bone and Mineral Research 36 (6), 1159-1173, 2020 | 28 | 2020 |
| Co-treatment of TGF-β3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments X Huang, L Zhong, JN Post, M Karperien Scientific reports 8 (1), 10251, 2018 | 28 | 2018 |
| Csf1 from marrow adipogenic precursors is required for osteoclast formation and hematopoiesis in bone L Zhong, J Lu, J Fang, L Yao, W Yu, T Gui, M Duffy, N Holdreith, ... Elife 12, e82112, 2023 | 25 | 2023 |
| Marrow adipogenic lineage precursor: A new cellular component of marrow adipose tissue L Zhong, L Yao, P Seale, L Qin Best Practice & Research Clinical Endocrinology & Metabolism 35 (4), 101518, 2021 | 25 | 2021 |
| EGFR signaling is required for maintaining adult cartilage homeostasis and attenuating osteoarthritis progression Y Wei, X Ma, H Sun, T Gui, J Li, L Yao, L Zhong, W Yu, B Han, CL Nelson, ... Journal of Bone and Mineral Research 37 (5), 1012-1023, 2020 | 23 | 2020 |
| The expressions of Dickkopf-related protein 1 and frizzled-related protein are negatively correlated to local inflammation and osteoarthritis severity X Huang, L Zhong, E van Helvoort, F Lafeber, S Mastbergen, J Hendriks, ... Cartilage 12 (4), 496-504, 2021 | 21 | 2021 |
| The critical role of Hedgehog-responsive mesenchymal progenitors in meniscus development and injury repair Y Wei, H Sun, T Gui, L Yao, L Zhong, W Yu, SJ Heo, L Han, NA Dyment, ... Elife 10, e62917, 2021 | 20 | 2021 |
