| Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo A Martelli, L Testai, V Citi, A Marino, I Pugliesi, E Barresi, G Nesi, ... ACS medicinal chemistry letters 4 (10), 904-908, 2013 | 177 | 2013 |
| Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs S Salerno, F Da Settimo, S Taliani, F Simorini, C La Motta, G Fornaciari, ... Current medicinal chemistry 17 (35), 4270-4290, 2010 | 165 | 2010 |
| Pyrido[1,2-a]pyrimidin-4-one Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors Exhibiting Antioxidant Activity C La Motta, S Sartini, L Mugnaini, F Simorini, S Taliani, S Salerno, ... Journal of Medicinal Chemistry 50 (20), 4917-4927, 2007 | 154 | 2007 |
| 11C-ER176, a radioligand for 18-kDa translocator protein, has adequate sensitivity to robustly image all three affinity genotypes in human brain M Ikawa, TG Lohith, S Shrestha, S Telu, SS Zoghbi, S Castellano, ... Journal of Nuclear Medicine 58 (2), 320-325, 2017 | 137 | 2017 |
| Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis F Da Settimo, F Simorini, S Taliani, C La Motta, AM Marini, S Salerno, ... Journal of medicinal chemistry 51 (18), 5798-5806, 2008 | 102 | 2008 |
| GABAA/Bz receptor subtypes as targets for selective drugs F Da Settimo, S Taliani, ML Trincavelli, M Montali, C Martini Current medicinal chemistry 14 (25), 2680-2701, 2007 | 101 | 2007 |
| N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor G Primofiore, F Da Settimo, S Taliani, F Simorini, MP Patrizi, E Novellino, ... Journal of medicinal chemistry 47 (7), 1852-1855, 2004 | 89 | 2004 |
| Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide … P Zanotti-Fregonara, Y Zhang, KJ Jenko, RL Gladding, SS Zoghbi, ... ACS chemical neuroscience 5 (10), 963-971, 2014 | 75 | 2014 |
| 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: A New Class of Selective A1 Adenosine Receptor Antagonists F Da Settimo, G Primofiore, S Taliani, AM Marini, C La Motta, E Novellino, ... Journal of medicinal chemistry 44 (3), 316-327, 2001 | 72 | 2001 |
| Apoptosis therapy in cancer: the first single-molecule co-activating p53 and the translocator protein in glioblastoma S Daniele, S Taliani, E Da Pozzo, C Giacomelli, B Costa, ML Trincavelli, ... Scientific reports 4 (1), 4749, 2014 | 70 | 2014 |
| Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation E Da Pozzo, C Tremolanti, B Costa, C Giacomelli, VM Milenkovic, S Bader, ... International journal of molecular sciences 20 (18), 4467, 2019 | 69 | 2019 |
| Genetic analysis of dTSPO, an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Aβ42‐induced neurodegeneration R Lin, A Angelin, F Da Settimo, C Martini, S Taliani, S Zhu, DC Wallace Aging cell 13 (3), 507-518, 2014 | 69 | 2014 |
| Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists B Cosimelli, G Greco, M Ehlardo, E Novellino, F Da Settimo, S Taliani, ... Journal of medicinal chemistry 51 (6), 1764-1770, 2008 | 67 | 2008 |
| The alpha keto amide moiety as a privileged motif in medicinal chemistry: current insights and emerging opportunities M Robello, E Barresi, E Baglini, S Salerno, S Taliani, FD Settimo Journal of Medicinal Chemistry 64 (7), 3508-3545, 2021 | 63 | 2021 |
| TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy B Costa, E Da Pozzo, C Giacomelli, E Barresi, S Taliani, F Da Settimo, ... Scientific Reports 6 (1), 18164, 2016 | 63 | 2016 |
| New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation S Taliani, F Simorini, V Sergianni, C La Motta, F Da Settimo, B Cosimelli, ... Journal of Medicinal Chemistry 50 (2), 404-407, 2007 | 63 | 2007 |
| 2-(Benzimidazol-2-yl)quinoxalines: A Novel Class of Selective Antagonists at Human A1 and A3 Adenosine Receptors Designed by 3D Database Searching E Novellino, B Cosimelli, M Ehlardo, G Greco, M Iadanza, A Lavecchia, ... Journal of medicinal chemistry 48 (26), 8253-8260, 2005 | 63 | 2005 |
| Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors F Da Settimo, G Primofiore, C La Motta, S Sartini, S Taliani, F Simorini, ... Journal of medicinal chemistry 48 (22), 6897-6907, 2005 | 62 | 2005 |
| Novel N2-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A3 Receptor Antagonists: Inhibition of A3-Mediated Human Glioblastoma Cell Proliferation S Taliani, C La Motta, L Mugnaini, F Simorini, S Salerno, AM Marini, ... Journal of medicinal chemistry 53 (10), 3954-3963, 2010 | 58 | 2010 |
| Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model C La Motta, S Sartini, S Salerno, F Simorini, S Taliani, AM Marini, ... Journal of medicinal chemistry 51 (11), 3182-3193, 2008 | 58 | 2008 |
