| Structural bioinformatics J Gu, PE Bourne John Wiley & Sons, 2009 | 541 | 2009 |
| Arpeggio: a web server for calculating and visualising interatomic interactions in protein structures HC Jubb, AP Higueruelo, B Ochoa-Montaño, WR Pitt, DB Ascher, ... Journal of molecular biology 429 (3), 365-371, 2017 | 380 | 2017 |
| Structural biology and drug discovery for protein–protein interactions H Jubb, AP Higueruelo, A Winter, TL Blundell Trends in pharmacological sciences 33 (5), 241-248, 2012 | 202 | 2012 |
| Atomic interactions and profile of small molecules disrupting protein–protein interfaces: the TIMBAL database AP Higueruelo, A Schreyer, GRJ Bickerton, WR Pitt, CR Groom, ... Chemical biology & drug design 74 (5), 457-467, 2009 | 194 | 2009 |
| Protein–protein interactions as druggable targets: recent technological advances AP Higueruelo, H Jubb, TL Blundell Current opinion in pharmacology 13 (5), 791-796, 2013 | 149 | 2013 |
| Biophysical and computational fragment-based approaches to targeting protein–protein interactions: applications in structure-guided drug discovery A Winter, AP Higueruelo, M Marsh, A Sigurdardottir, WR Pitt, TL Blundell Quarterly reviews of biophysics 45 (4), 383-426, 2012 | 129 | 2012 |
| IRAK-4 inhibitors. Part III: a series of imidazo [1, 2-a] pyridines GM Buckley, R Fosbeary, JL Fraser, L Gowers, AP Higueruelo, LA James, ... Bioorganic & medicinal chemistry letters 18 (12), 3656-3660, 2008 | 96 | 2008 |
| TIMBAL v2: update of a database holding small molecules modulating protein–protein interactions AP Higueruelo, H Jubb, TL Blundell Database 2013, bat039, 2013 | 89 | 2013 |
| IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo [1, 2-a] pyridine binding GM Buckley, TA Ceska, JL Fraser, L Gowers, CR Groom, AP Higueruelo, ... Bioorganic & medicinal chemistry letters 18 (11), 3291-3295, 2008 | 87 | 2008 |
| Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database GR Bickerton, AP Higueruelo, TL Blundell BMC bioinformatics 12, 1-15, 2011 | 73 | 2011 |
| IRAK-4 inhibitors. Part 1: A series of amides GM Buckley, L Gowers, AP Higueruelo, K Jenkins, SR Mack, T Morgan, ... Bioorganic & medicinal chemistry letters 18 (11), 3211-3214, 2008 | 69 | 2008 |
| A DFT computational study of the bis-silylation reaction of acetylene catalyzed by palladium complexes A Bottoni, AP Higueruelo, GP Miscione Journal of the American Chemical Society 124 (19), 5506-5513, 2002 | 41 | 2002 |
| What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics? AP Higueruelo, A Schreyer, GRJ Bickerton, TL Blundell, WR Pitt PLoS One 7 (12), e51742, 2012 | 27 | 2012 |
| Hotspots api: a python package for the detection of small molecule binding hotspots and application to structure-based drug design PR Curran, CJ Radoux, MD Smilova, RA Sykes, AP Higueruelo, ... Journal of chemical information and modeling 60 (4), 1911-1916, 2020 | 20 | 2020 |
| Biomolecular forms and functions: a celebration of 50 years of the Ramachandran map M Gupta World Scientific, 2013 | 19 | 2013 |
| Protein-protein interactions: structures and druggability DB Ascher, HC Jubb, DEV Pires, T Ochi, A Higueruelo, TL Blundell Multifaceted roles of crystallography in modern drug discovery, 141-163, 2015 | 14 | 2015 |
| SInCRe—structural interactome computational resource for Mycobacterium tuberculosis R Metri, S Hariharaputran, G Ramakrishnan, P Anand, US Raghavender, ... Database 2015, bav060, 2015 | 12 | 2015 |
| Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics S Lee, A Brown, WR Pitt, AP Higueruelo, S Gong, GR Bickerton, ... Molecular Biosystems 5 (12), 1456-1472, 2009 | 10 | 2009 |
| TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species S Malhotra, G Mugumbate, TL Blundell, AP Higueruelo Database 2017, bax041, 2017 | 7 | 2017 |
| Fragment-Based Methods for Lead Discovery NP Pitt, WR Higueruelo, AP Todorov In silico lead discovery, 83-116, 2010 | 6* | 2010 |
Tom L BlundellEmeritus Professor of Biochemistry, University of CambridgeVerified email at cam.ac.uk
