mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex JT Cunningham, JT Rodgers, DH Arlow, F Vazquez, VK Mootha, ... nature 450 (7170), 736-740, 2007 | 1650 | 2007 |
Structure and dynamics of the M3 muscarinic acetylcholine receptor AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ... Nature 482 (7386), 552-556, 2012 | 911 | 2012 |
Structure and function of an irreversible agonist-β2 adrenoceptor complex DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ... Nature 469 (7329), 236-240, 2011 | 911 | 2011 |
The dynamic process of β2-adrenergic receptor activation R Nygaard, Y Zou, RO Dror, TJ Mildorf, DH Arlow, A Manglik, AC Pan, ... Cell 152 (3), 532-542, 2013 | 885 | 2013 |
Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle VK Mootha, C Handschin, D Arlow, X Xie, J St. Pierre, S Sihag, W Yang, ... Proceedings of the National Academy of Sciences 101 (17), 6570-6575, 2004 | 836 | 2004 |
Pathway and mechanism of drug binding to G-protein-coupled receptors RO Dror, AC Pan, DH Arlow, DW Borhani, P Maragakis, Y Shan, H Xu, ... Proceedings of the National Academy of Sciences 108 (32), 13118-13123, 2011 | 803 | 2011 |
Activation mechanism of the β2-adrenergic receptor RO Dror, DH Arlow, P Maragakis, TJ Mildorf, AC Pan, H Xu, DW Borhani, ... Proceedings of the National Academy of Sciences 108 (46), 18684-18689, 2011 | 628 | 2011 |
High-resolution crystal structure of human protease-activated receptor 1 C Zhang, Y Srinivasan, DH Arlow, JJ Fung, D Palmer, Y Zheng, HF Green, ... Nature 492 (7429), 387-392, 2012 | 528 | 2012 |
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs RO Dror, HF Green, C Valant, DW Borhani, JR Valcourt, AC Pan, ... Nature 503 (7475), 295-299, 2013 | 432 | 2013 |
Identification Of Two Distinct Inactive Conformations Of The Beta-2 Adrenergic Receptor Reconciles Structural And Biochemical Observations RO Dror, DH Arlow, DW Borhani, M Jensen, DE Shaw Biophysical Journal 96 (3), 365a, 2009 | 374 | 2009 |
Structural basis for nucleotide exchange in heterotrimeric G proteins RO Dror, TJ Mildorf, D Hilger, A Manglik, DW Borhani, DH Arlow, ... Science 348 (6241), 1361-1365, 2015 | 312 | 2015 |
De novo DNA synthesis using polymerase-nucleotide conjugates S Palluk, DH Arlow, T De Rond, S Barthel, JS Kang, R Bector, ... Nature biotechnology 36 (7), 645-650, 2018 | 256 | 2018 |
A computational screen for regulators of oxidative phosphorylation implicates SLIRP in mitochondrial RNA homeostasis JM Baughman, R Nilsson, VM Gohil, DH Arlow, Z Gauhar, VK Mootha PLoS genetics 5 (8), e1000590, 2009 | 186 | 2009 |
The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions A Charest-Marcotte, CR Dufour, BJ Wilson, AM Tremblay, LJ Eichner, ... Genes & development 24 (6), 537-542, 2010 | 155 | 2010 |
Enhancing terminal deoxynucleotidyl transferase activity on substrates with 3′ terminal structures for enzymatic de novo DNA synthesis S Barthel, S Palluk, NJ Hillson, JD Keasling, DH Arlow Genes 11 (1), 102, 2020 | 33 | 2020 |
Activation mechanism of the β2-adrenergic receptor RO Dror, DH Arlow, P Maragakis, TJ Mildorf, AC Pan, H Xu, DW Borhani, ... Biophysical Journal 102 (3), 239a, 2012 | 5 | 2012 |
Spatially Selective Electrochemical Cleavage of a Polymerase-Nucleotide Conjugate JA Smith, BH Nguyen, R Carlson, JG Bertram, S Palluk, DH Arlow, ... ACS Synthetic Biology 12 (6), 1716-1726, 2023 | 4 | 2023 |
Polymerase-tethered nucleoside triphosphates for use in nucleic acid synthesis D Arlow, S Palluk US Patent 11,254,961, 2022 | 4 | 2022 |
Probing the conformational dynamics of GPCRs with molecular dynamics simulation RO Dror, AC Pan, DH Arlow, DE Shaw | 2 | 2011 |
Nucleic acid synthesis and sequencing using tethered nucleoside triphosphates D Arlow, S Palluk US Patent 11,732,283, 2023 | 1 | 2023 |