Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells JD Grevet, X Lan, N Hamagami, CR Edwards, L Sankaranarayanan, X Ji, ...
Science 361 (6399), 285-290, 2018
142 2018 Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element P Huang, CA Keller, B Giardine, JD Grevet, JOJ Davies, JR Hughes, ...
Genes & development 31 (16), 1704-1713, 2017
124 2017 Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins AP Siebert, Z Ma, JD Grevet, A Demuro, I Parker, JK Foskett
Journal of Biological Chemistry 288 (9), 6140-6153, 2013
124 2013 ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression X Lan, R Ren, R Feng, LC Ly, Y Lan, Z Zhang, N Aboreden, K Qin, ...
Molecular cell 81 (2), 239-254. e8, 2021
57 2021 Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus V Leinonen, LG Menon, RS Carroll, D Dello Iacono, J Grevet, ...
International journal of Alzheimer’s disease 2011, 2011
49 2011 The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells X Lan, E Khandros, P Huang, SA Peslak, SK Bhardwaj, JD Grevet, ...
Blood Advances 3 (10), 1586-1597, 2019
31 2019 HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation SA Peslak, E Khandros, P Huang, X Lan, CL Geronimo, JD Grevet, ...
Blood Advances 4 (18), 4560-4572, 2020
16 2020 Genome editing recreates hereditary persistence of fetal hemoglobin in primary human erythroblasts E Traxler, Y Yao, C Li, J Grevet, P Huang, S Wright, GA Blobel, MJ Weiss
Blood 126 (23), 640, 2015
9 2015 Knotted and Linked Products of recombination on T (2, n)# T (2, m) Substrates E Flapan, J Grevet, Q Li, CD Sun, H Wong
3 2014 Domain-focused CRISPR-Cas9 screen identifies the E3 ubiquitin ligase substrate adaptor protein SPOP as a novel repressor of fetal hemoglobin X Lan, E Khandros, JD Grevet, SA Peslak, S Bhardwaj, CA Keller, ...
Blood 132 (Supplement 1), 414-414, 2018
1 2018 Knotted and linked products of recombination on E Flapan, J Grevet, Q Li, C Sun, H Wong
arXiv preprint arXiv:1311.5456, 2013
1 2013 Compositions and methods for hemoglobin production G Blobel, J Grevet, J Shi, C Vakoc
US Patent App. 17/532,123, 2022
2022 Compositions and methods for hemoglobin production G Blobel, J Grevet, J Shi, C Vakoc
US Patent 11,179,379, 2021
2021 Heme-Regulated Inhibitor (HRI) Depletion Cooperates with Pharmacologic Inducers to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation SA Peslak, X Lan, E Khandros, P Huang, JA Yano, JD Grevet, ...
Blood 134, 3557, 2019
2019 Interrogating RNA Binding Proteins as Novel Regulators of Fetal Hemoglobin Expression A Wakabayashi, JD Grevet, X Lan, M Sharma, J Shi, GA Blobel
Blood 134, 966, 2019
2019 Heme-Regulated Inhibitor (HRI) Loss and Pharmacologic Treatments Cooperate to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation SA Peslak, JD Grevet, X Lan, O Abdulmalik, J Shi, GA Blobel
Blood 132, 721, 2018
2018 Compositions and methods for hemoglobin production G Blobel, J GREVET, J Shi, C Vakoc
2018 Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells JD Grevet, N Hamagami, X Lan, L Sankaranarayanan, S Bhardwaj, ...
Blood 130, 536, 2017
2017 Mechanistic Insights into Forced Chromatin Looping Mediated Activation of Fetal Globin Gene Expression C Bartman, GA Blobel, J Grevet, CCS Hsiung, JW Rupon, A Raj
Blood 124 (21), 331, 2014
2014 Keeping fetal hemoglobin in the loop JD Grevet, GA Blobel
Cell Cycle 13 (20), 3153-3154, 2014
2014 