Jason H. Moore
Jason H. Moore
Professor and Director, Institute for Biomedical Informatics, University of Pennsylvania
Verified email at upenn.edu - Homepage
TitleCited byYear
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
MD Ritchie, LW Hahn, N Roodi, LR Bailey, WD Dupont, FF Parl, JH Moore
The American Journal of Human Genetics 69 (1), 138-147, 2001
19152001
Missing heritability and strategies for finding the underlying causes of complex disease
EE Eichler, J Flint, G Gibson, A Kong, SM Leal, JH Moore, JH Nadeau
Nature Reviews Genetics 11 (6), 446-450, 2010
14712010
The genetic structure and history of Africans and African Americans
SA Tishkoff, FA Reed, FR Friedlaender, C Ehret, A Ranciaro, A Froment, ...
science 324 (5930), 1035-1044, 2009
12972009
Multifactor dimensionality reduction software for detecting gene–gene and gene–environment interactions
LW Hahn, MD Ritchie, JH Moore
Bioinformatics 19 (3), 376-382, 2003
11462003
Genome-wide association studies
WS Bush, JH Moore
PLoS computational biology 8 (12), 2012
9722012
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
A Gaur, DA Jewell, Y Liang, D Ridzon, JH Moore, C Chen, VR Ambros, ...
Cancer research 67 (6), 2456-2468, 2007
7812007
The ubiquitous nature of epistasis in determining susceptibility to common human diseases
JH Moore
Human heredity 56 (1-3), 73-82, 2003
7582003
Proteomic patterns of tumour subsets in non-small-cell lung cancer
K Yanagisawa, Y Shyr, BJ Xu, PP Massion, PH Larsen, BC White, ...
The Lancet 362 (9382), 433-439, 2003
7342003
A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility
JH Moore, JC Gilbert, CT Tsai, FT Chiang, T Holden, N Barney, BC White
Journal of theoretical biology 241 (2), 252-261, 2006
6272006
Power of multifactor dimensionality reduction for detecting gene‐gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity
MD Ritchie, LW Hahn, JH Moore
Genetic Epidemiology: The Official Publication of the International Genetic …, 2003
5732003
Bioinformatics challenges for genome-wide association studies
JH Moore, FW Asselbergs, SM Williams
Bioinformatics 26 (4), 445-455, 2010
5172010
A high-density admixture map for disease gene discovery in African Americans
MW Smith, N Patterson, JA Lautenberger, AL Truelove, GJ McDonald, ...
The American Journal of Human Genetics 74 (5), 1001-1013, 2004
4452004
Renin-angiotensin system gene polymorphisms and atrial fibrillation
CT Tsai, LP Lai, JL Lin, FT Chiang, JJ Hwang, MD Ritchie, JH Moore, ...
Circulation 109 (13), 1640-1646, 2004
4402004
New strategies for identifying gene-gene interactions in hypertension
JH Moore, SM Williams
Annals of medicine 34 (2), 88-95, 2002
4092002
A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction
DR Velez, BC White, AA Motsinger, WS Bush, MD Ritchie, SM Williams, ...
Genetic Epidemiology: the Official Publication of the International Genetic …, 2007
3432007
Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis
JH Moore, SM Williams
Bioessays 27 (6), 637-646, 2005
3272005
Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort
L Shen, S Kim, SL Risacher, K Nho, S Swaminathan, JD West, T Foroud, ...
Neuroimage 53 (3), 1051-1063, 2010
3102010
Epistasis and its implications for personal genetics
JH Moore, SM Williams
The American Journal of Human Genetics 85 (3), 309-320, 2009
3012009
Genetics, statistics and human disease: analytical retooling for complexity
TA Thornton-Wells, JH Moore, JL Haines
TRENDS in Genetics 20 (12), 640-647, 2004
2962004
Computational analysis of gene-gene interactions using multifactor dimensionality reduction
JH Moore
Expert review of molecular diagnostics 4 (6), 795-803, 2004
2722004
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Articles 1–20