Dimitris Kletsas
Dimitris Kletsas
Research Director, NCSR "Demokritos"
Verified email at bio.demokritos.gr
TitleCited byYear
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
VG Gorgoulis, LVF Vassiliou, P Karakaidos, P Zacharatos, A Kotsinas, ...
Nature 434 (7035), 907, 2005
19862005
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
J Bartkova, N Rezaei, M Liontos, P Karakaidos, D Kletsas, N Issaeva, ...
Nature 444 (7119), 633, 2006
17252006
The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells
PG Ziros, APR Gil, T Georgakopoulos, I Habeos, D Kletsas, EK Basdra, ...
Journal of Biological Chemistry 277 (26), 23934-23941, 2002
3172002
Senescence in human intervertebral discs
S Roberts, EH Evans, D Kletsas, DC Jaffray, SM Eisenstein
European Spine Journal 15 (3), 312-316, 2006
2512006
Human fibroblast alterations induced by low power laser irradiation at the single cell level using confocal microscopy
E Alexandratou, D Yova, P Handris, D Kletsas, S Loukas
Photochemical & Photobiological Sciences 1 (8), 547-552, 2002
2122002
Inflammatory and catabolic signalling in intervertebral discs: the roles of NF-KB and MAP kinases
K Wuertz, N Vo, D Kletsas, N Boos
Eur Cell Mater 23, 103-19, 2012
1702012
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior
M Liontos, M Koutsami, M Sideridou, K Evangelou, D Kletsas, B Levy, ...
Cancer research 67 (22), 10899-10909, 2007
1692007
PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways
H Pratsinis, D Kletsas
European Spine Journal 16 (11), 1858-1866, 2007
1632007
Transcription factor E2F‐1 acts as a growth‐promoting factor and is associated with adverse prognosis in non‐small cell lung carcinomas
VG Gorgoulis, P Zacharatos, G Mariatos, A Kotsinas, M Bouda, D Kletsas, ...
The Journal of pathology 198 (2), 142-156, 2002
1612002
Bioactive non-coloured polyphenols content of grapes, wines and vinification by-products: Evaluation of the antioxidant activities of their extracts
M Anastasiadi, H Pratsinis, D Kletsas, AL Skaltsounis, SA Haroutounian
Food research international 43 (3), 805-813, 2010
1452010
Characterization and cytotoxicity of ions released from stainless steel and nickel-titanium orthodontic alloys
T Eliades, H Pratsinis, D Kletsas, G Eliades, M Makou
American Journal of Orthodontics and Dentofacial Orthopedics 125 (1), 24-29, 2004
1452004
Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex
IP Trougakos, M Lourda, MH Antonelou, D Kletsas, VG Gorgoulis, ...
Clinical cancer research 15 (1), 48-59, 2009
1412009
Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues
EA Georgakopoulou, K Tsimaratou, K Evangelou, MPJ Fernandez, ...
Aging (Albany NY) 5 (1), 37, 2013
1372013
Resveratrol and related stilbenes: their anti-aging and anti-angiogenic properties
KM Kasiotis, H Pratsinis, D Kletsas, SA Haroutounian
Food and chemical toxicology 61, 112-120, 2013
1282013
Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption
MS Oitzl, ER de Kloet, M JoŽls, W Schmid, TJ Cole
European Journal of Neuroscience 9 (11), 2284-2296, 1997
1221997
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ...
Nature cell biology 18 (7), 777, 2016
1212016
In vitro cytostatic and immunomodulatory properties of the medicinal mushroom Lentinula edodes
C Israilides, D Kletsas, D Arapoglou, A Philippoussis, H Pratsinis, ...
Phytomedicine 15 (6-7), 512-519, 2008
1152008
Molecular mechanisms of biological aging in intervertebral discs
NV Vo, RA Hartman, PR Patil, MV Risbud, D Kletsas, JC Iatridis, ...
Journal of orthopaedic research 34 (8), 1289-1306, 2016
1132016
Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors
OC Kousidou, TN Mitropoulou, AE Roussidis, D Kletsas, AD Theocharis, ...
International journal of oncology 26 (4), 1101-1109, 2005
1042005
Peripheral-type benzodiazepine receptor (PBR) and PBR drug ligands in fibroblast and fibrosarcoma cell proliferation: role of ERK, c-Jun and ligand-activated PBR-independent†…
D Kletsas, W Li, Z Han, V Papadopoulos
Biochemical pharmacology 67 (10), 1927-1932, 2004
1042004
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