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Jurgen R Haanstra
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Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei
MA Albert, JR Haanstra, V Hannaert, J Van Roy, FR Opperdoes, ...
Journal of Biological Chemistry 280 (31), 28306-28315, 2005
2102005
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
JR Haanstra, A van Tuijl, P Kessler, W Reijnders, PAM Michels, ...
Proceedings of the National Academy of Sciences 105 (46), 17718-17723, 2008
1862008
Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia
R Beekman, MG Valkhof, MA Sanders, PMH Van Strien, JR Haanstra, ...
Blood, The Journal of the American Society of Hematology 119 (22), 5071-5077, 2012
1812012
Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites
JR Haanstra, EB González-Marcano, M Gualdrón-López, PAM Michels
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (5), 1038-1048, 2016
1412016
Transcriptome‐wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co‐transcriptional degradation in determining mRNA levels
A Fadda, M Ryten, D Droll, F Rojas, V Färber, JR Haanstra, C Merce, ...
Molecular microbiology 94 (2), 307-326, 2014
1222014
EVI1 is critical for the pathogenesis of a subset of MLL-AF9–rearranged AMLs
EMJ Bindels, M Havermans, S Lugthart, C Erpelinck, E Wocjtowicz, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5838-5849, 2012
922012
Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei
JR Haanstra, M Stewart, VD Luu, A van Tuijl, HV Westerhoff, C Clayton, ...
Journal of Biological Chemistry 283 (5), 2495-2507, 2008
882008
Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event
MJH Kas, AW Bruijnzeel, JR Haanstra, VM Wiegant, RAH Adan
Journal of molecular endocrinology 35 (1), 159-164, 2005
792005
Lineage-instructive function of C/EBPá in multipotent hematopoietic cells and early thymic progenitors
A Wölfler, AA Danen-van Oorschot, JR Haanstra, M Valkhof, C Bodner, ...
Blood, The Journal of the American Society of Hematology 116 (20), 4116-4125, 2010
712010
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism
S Pieretti, JR Haanstra, M Mazet, R Perozzo, C Bergamini, F Prati, R Fato, ...
PLoS neglected tropical diseases 7 (1), e2012, 2013
632013
A domino effect in drug action: from metabolic assault towards parasite differentiation
JR Haanstra, EJ Kerkhoven, A Van Tuijl, M Blits, M Wurst, R Van Nuland, ...
Molecular microbiology 79 (1), 94-108, 2011
582011
Targeting pathogen metabolism without collateral damage to the host
JR Haanstra, A Gerding, AM Dolga, FJ Sorgdrager, M Buist-Homan, ...
Scientific Reports 7, 40406, 2017
572017
Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis
A Nilsson, JR Haanstra, M Engqvist, A Gerding, BM Bakker, U Klingmüller, ...
Proceedings of the National Academy of Sciences 117 (19), 10294-10304, 2020
512020
Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal …
EB Antwi, JR Haanstra, G Ramasamy, B Jensen, D Droll, F Rojas, I Minia, ...
BMC genomics 17, 1-16, 2016
512016
ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation
MF Alemdehy, JR Haanstra, HWJ de Looper, PMH van Strien, ...
Blood, The Journal of the American Society of Hematology 125 (25), 3937-3948, 2015
502015
Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids
B Szöör, JR Haanstra, M Gualdrón-López, PAM Michels
Current Opinion in Microbiology 22, 79-87, 2014
502014
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux
E Bosdriesz, MT Wortel, JR Haanstra, MJ Wagner, P De La Torre Cortes, ...
Scientific reports 8 (1), 1-9, 2018
452018
Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes
JR Haanstra, A van Tuijl, J van Dam, W van Winden, AGM Tielens, ...
International journal for parasitology 42 (7), 667-673, 2012
432012
Network-based selectivity of antiparasitic inhibitors
BM Bakker, HE Assmus, F Bruggeman, JR Haanstra, E Klipp, ...
Molecular biology reports 29 (1-2), 1-5, 2002
372002
Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling
AE Leroux, JR Haanstra, BM Bakker, RL Krauth-Siegel
Journal of Biological Chemistry 288 (33), 23751-23764, 2013
332013
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