A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability GL Amidon, H Lennernäs, VP Shah, JR Crison Pharmaceutical research 12 (3), 413-420, 1995 | 7314 | 1995 |
Molecular properties of WHO essential drugs and provisional biopharmaceutical classification NA Kasim, M Whitehouse, C Ramachandran, M Bermejo, H Lennernäs, ... Molecular pharmaceutics 1 (1), 85-96, 2004 | 1059 | 2004 |
Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors H Lennernäs, G Fager Clinical pharmacokinetics 32 (5), 403-425, 1997 | 753 | 1997 |
Clinical pharmacokinetics of atorvastatin H Lennernäs Clinical pharmacokinetics 42 (13), 1141-1160, 2003 | 724 | 2003 |
Coexistence of passive and carrier-mediated processes in drug transport K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ... Nature reviews Drug discovery 9 (8), 597-614, 2010 | 700 | 2010 |
Comparison between permeability coefficients in rat and human jejunum U Fagerholm, M Johansson, H Lennernäs Pharmaceutical research 13 (9), 1336-1342, 1996 | 619 | 1996 |
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach S Winiwarter, NM Bonham, F Ax, A Hallberg, H Lennernäs, A Karlén Journal of medicinal chemistry 41 (25), 4939-4949, 1998 | 552 | 1998 |
Characterization of fluids from the stomach and proximal jejunum in men and women A Lindahl, AL Ungell, L Knutson, H Lennernäs Pharmaceutical research 14 (4), 497-502, 1997 | 479 | 1997 |
Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation G Johannsson, AG Nilsson, R Bergthorsdottir, P Burman, P Dahlqvist, ... The Journal of Clinical Endocrinology & Metabolism 97 (2), 473-481, 2012 | 351 | 2012 |
Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in vitro and human jejunum in vivo H Lennernäs, K Palm, U Fagerholm, P Artursson International journal of pharmaceutics 127 (1), 103-107, 1996 | 337 | 1996 |
Membrane transport of drugs in different regions of the intestinal tract of the rat AL Ungell, S Nylander, S Bergstrand, Å Sjöberg, H Lennernäs Journal of pharmaceutical sciences 87 (3), 360-366, 1998 | 330 | 1998 |
The effects of food on the dissolution of poorly soluble drugs in human and in model small intestinal fluids EM Persson, AS Gustafsson, AS Carlsson, RG Nilsson, L Knutson, ... Pharmaceutical research 22 (12), 2141-2151, 2005 | 313 | 2005 |
Intestinal permeability and its relevance for absorption and elimination H Lennernäs Xenobiotica 37 (10-11), 1015-1051, 2007 | 305 | 2007 |
In vivo methods for drug absorption–comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient … E Sjögren, B Abrahamsson, P Augustijns, D Becker, MB Bolger, ... European Journal of Pharmaceutical Sciences 57, 99-151, 2014 | 298 | 2014 |
Optimizing levodopa pharmacokinetics: intestinal infusion versus oral sustained-release tablets D Nyholm, H Askmark, C Gomes–Trolin, T Knutson, H Lennernäs, ... Clinical neuropharmacology 26 (3), 156-163, 2003 | 298 | 2003 |
Chitosans as absorption enhancers of poorly absorbable drugs: 3: Influence of mucus on absorption enhancement NGM Schipper, KM Vårum, P Stenberg, G Ocklind, H Lennernäs, ... European journal of pharmaceutical sciences 8 (4), 335-343, 1999 | 291 | 1999 |
Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man H Lennernäs, Ö Ahrenstedt, R Hällgren, L Knutson, M Ryde, LK Paalzow Pharmaceutical research 9 (10), 1243-1251, 1992 | 291 | 1992 |
The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension H Lennernäs, B Abrahamsson Journal of pharmacy and pharmacology 57 (3), 273-285, 2005 | 289 | 2005 |
Human jejunal effective permeability and its correlation with preclinical drug absorption models H LennernÄs Journal of Pharmacy and Pharmacology 49 (7), 627-638, 1997 | 280 | 1997 |
Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine S Berggren, C Gall, N Wollnitz, M Ekelund, U Karlbom, J Hoogstraate, ... Molecular pharmaceutics 4 (2), 252-257, 2007 | 243 | 2007 |