Παρακολούθηση
Leonidas Stefanis
Leonidas Stefanis
Prof. Neurology-Neurobiology, Medical School, National and Kapodistrian University of Athens
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα med.uoa.gr - Αρχική σελίδα
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
91732021
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo, L Stefanis, R Fredenburg, PT Lansbury, D Sulzer
Science 305 (5688), 1292-1295, 2004
21932004
α-Synuclein in Parkinson's disease
L Stefanis
Cold Spring Harbor perspectives in medicine 2 (2), a009399, 2012
11462012
Cell-produced α-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival
E Emmanouilidou, K Melachroinou, T Roumeliotis, SD Garbis, M Ntzouni, ...
Journal of Neuroscience 30 (20), 6838-6851, 2010
10882010
Expression of A53T mutant but not wild-type α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and …
L Stefanis, KE Larsen, HJ Rideout, D Sulzer, LA Greene
Journal of Neuroscience 21 (24), 9549-9560, 2001
7192001
Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
T Vogiatzi, M Xilouri, K Vekrellis, L Stefanis
Journal of Biological Chemistry 283 (35), 23542-23556, 2008
6732008
Autophagy and its possible roles in nervous system diseases, damage and repair
DC Rubinsztein, M DiFiglia, N Heintz, RA Nixon, ZH Qin, B Ravikumar, ...
Autophagy 1 (1), 11-22, 2005
5192005
α-Synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis
KE Larsen, Y Schmitz, MD Troyer, E Mosharov, P Dietrich, AZ Quazi, ...
Journal of Neuroscience 26 (46), 11915-11922, 2006
4842006
Pathological roles of α-synuclein in neurological disorders
K Vekrellis, M Xilouri, E Emmanouilidou, HJ Rideout, L Stefanis
The Lancet Neurology 10 (11), 1015-1025, 2011
4122011
Abberant α-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy
M Xilouri, T Vogiatzi, K Vekrellis, D Park, L Stefanis
PloS one 4 (5), e5515, 2009
3802009
Proteasomal inhibition leads to formation of ubiquitin/α‐synuclein‐immunoreactive inclusions in PC12 cells
HJ Rideout, KE Larsen, D Sulzer, L Stefanis
Journal of neurochemistry 78 (4), 899-908, 2001
3632001
α-Synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells
XM Peng, R Tehranian, P Dietrich, L Stefanis, RG Perez
Journal of cell science 118 (15), 3523-3530, 2005
3022005
Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case–control study
OA Ross, AI Soto-Ortolaza, MG Heckman, JO Aasly, N Abahuni, G Annesi, ...
The Lancet Neurology 10 (10), 898-908, 2011
3002011
Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress
DS Park, EJ Morris, L Stefanis, CM Troy, ML Shelanski, HM Geller, ...
Journal of Neuroscience 18 (3), 830-840, 1998
2911998
Alpha-synuclein and protein degradation systems: a reciprocal relationship
M Xilouri, OR Brekk, L Stefanis
Molecular neurobiology 47 (2), 537-551, 2013
2732013
The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation.
CM Troy, L Stefanis, A Prochiantz, LA Greene, ML Shelanski
Proceedings of the National Academy of Sciences 93 (11), 5635-5640, 1996
2631996
Caspase-dependent and-independent death of camptothecin-treated embryonic cortical neurons
L Stefanis, DS Park, WJ Friedman, LA Greene
Journal of Neuroscience 19 (15), 6235-6247, 1999
2421999
Cell-produced α-synuclein oligomers are targeted to, and impair, the 26S proteasome
E Emmanouilidou, L Stefanis, K Vekrellis
Neurobiology of aging 31 (6), 953-968, 2010
2402010
Ordering the cell death pathway: differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in …
DS Park, L Stefanis, CYI Yan, SE Farinelli, LA Greene
Journal of Biological Chemistry 271 (36), 21898-21905, 1996
2401996
Autophagy and A lpha‐S ynuclein: R elevance to P arkinson's D isease and R elated S ynucleopathies
M Xilouri, OR Brekk, L Stefanis
Movement Disorders 31 (2), 178-192, 2016
2372016
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