| A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis G Bhabha, J Lee, DC Ekiert, J Gam, IA Wilson, HJ Dyson, SJ Benkovic, ... Science 332 (6026), 234-238, 2011 | 525 | 2011 |
| Surface sites for engineering allosteric control in proteins J Lee, M Natarajan, VC Nashine, M Socolich, T Vo, WP Russ, ... Science 322 (5900), 438-442, 2008 | 386 | 2008 |
| Catalytic contributions from remote regions of enzyme structure J Lee, NM Goodey Chemical reviews 111 (12), 7595-7624, 2011 | 97 | 2011 |
| NMR structural analysis of a modular threading tetraintercalator bound to DNA J Lee, V Guelev, S Sorey, DW Hoffman, BL Iverson Journal of the American Chemical Society 126 (43), 14036-14042, 2004 | 69 | 2004 |
| Peptide bis-intercalator binds DNA via threading mode with sequence specific contacts in the major groove V Guelev, J Lee, J Ward, S Sorey, DW Hoffman, BL Iverson Chemistry & Biology 8 (5), 415-425, 2001 | 61 | 2001 |
| LOVely enzymes–towards engineering light‐controllable biocatalysts U Krauss, J Lee, SJ Benkovic, KE Jaeger Microbial biotechnology 3 (1), 15-23, 2010 | 60 | 2010 |
| Mitochondria-targeting indolizino [3, 2-c] quinolines as novel class of photosensitizers for photodynamic anticancer activity S Kwon, Y Lee, Y Jung, JH Kim, B Baek, B Lim, J Lee, I Kim, J Lee European journal of medicinal chemistry 148, 116-127, 2018 | 57 | 2018 |
| When indolizine meets quinoline: Diversity-oriented synthesis of new polyheterocycles and their optical properties S Park, DI Kwon, J Lee, I Kim ACS Combinatorial Science 17 (8), 459-469, 2015 | 55 | 2015 |
| Deguelin analogue SH-1242 inhibits Hsp90 activity and exerts potent anticancer efficacy with limited neurotoxicity SC Lee, HY Min, H Choi, SY Bae, KH Park, SY Hyun, HJ Lee, J Moon, ... Cancer research 76 (3), 686-699, 2016 | 48 | 2016 |
| The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed hydride-transfer V Stojković, LL Perissinotti, J Lee, SJ Benkovic, A Kohen Chemical communications 46 (47), 8974-8976, 2010 | 42 | 2010 |
| Dual-functioning IQ-LVs as lysosomal viscosity probes with red-shifted emission and inhibitors of autophagic flux J Park, B Lim, NK Lee, JH Lee, K Jang, S Kim, I Kim, H Hwang, J Lee Sensors and Actuators B: Chemical 309, 127764, 2020 | 35 | 2020 |
| Novel turn-on fluorescent biosensors for selective detection of cellular Fe3+ in lysosomes: Thiophene as a selectivity-tuning handle for Fe3+ sensors B Lim, B Baek, K Jang, NK Lee, JH Lee, Y Lee, J Kim, J Park, S Kim, ... Dyes and Pigments 169, 51-59, 2019 | 29 | 2019 |
| Kinetic and Structural Characterization of Dihydrofolate Reductase from Streptococcus pneumoniae J Lee, NH Yennawar, J Gam, SJ Benkovic Biochemistry 49 (1), 195-206, 2010 | 29 | 2010 |
| A peptoid-based fluorescent sensor for cyanide detection B Lim, J Lee Molecules 21 (3), 339, 2016 | 27 | 2016 |
| A new ring expansion reaction of 1-acyl-2-vinylpiperidine and 1-acyl-2-vinylpiperazine via aza-Claisen rearrangement of amide enolate YG Suh, JY Lee, SA Kim, JK Jung Synthetic communications 26 (9), 1675-1680, 1996 | 25 | 1996 |
| Intramolecular Electrophilic Cyclization Approach to 6-Substituted Naphtho[2,1-b]benzofurans: Novel Dual-State Emissive Fluorophores with Blue Emission DK Singh, K Jang, J Kim, J Lee, I Kim ACS Combinatorial Science 21 (5), 408-416, 2019 | 21 | 2019 |
| Facile approach to benzo [d] imidazole-pyrrolo [1, 2-a] pyrazine hybrid structures through double cyclodehydration and aromatization and their unique optical properties with … GH Bae, S Kim, NK Lee, A Dagar, JH Lee, J Lee, I Kim RSC advances 10 (12), 7265-7288, 2020 | 20 | 2020 |
| Design, synthesis, and biological evaluation of proteolysis targeting chimeras (PROTACs) for the dual degradation of IGF-1R and Src S Manda, NK Lee, DC Oh, J Lee Molecules 25 (8), 1948, 2020 | 18 | 2020 |
| Indolizino [3, 2-c] quinolines as environment-sensitive fluorescent light-up probes for targeted live cell imaging S Kwon, DI Kwon, Y Jung, JH Kim, Y Lee, B Lim, I Kim, J Lee Sensors and Actuators B: Chemical 252, 340-352, 2017 | 16 | 2017 |
| Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity HJ Lee, PC Pham, SY Hyun, B Baek, B Kim, Y Kim, HY Min, J Lee, ... Molecular Cancer 17, 1-16, 2018 | 14 | 2018 |
