IL-10-generated tolerogenic dendritic cells are optimal for functional regulatory T cell induction—a comparative study of human clinical-applicable DC MA Boks, JR Kager-Groenland, MSP Haasjes, JJ Zwaginga, SM van Ham, ... Clinical immunology 142 (3), 332-342, 2012 | 304 | 2012 |
CD8+ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung B Piet, GJ de Bree, BS Smids-Dierdorp, CM van der Loos, ... The Journal of clinical investigation 121 (6), 2254-2263, 2011 | 202 | 2011 |
Hurdles in therapy with regulatory T cells P Trzonkowski, R Bacchetta, M Battaglia, D Berglund, HR Bohnenkamp, ... Science translational medicine 7 (304), 304ps18-304ps18, 2015 | 177 | 2015 |
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation P Paul, T Van Den Hoorn, MLM Jongsma, MJ Bakker, R Hengeveld, ... Cell 145 (2), 268-283, 2011 | 169 | 2011 |
The costimulatory molecule CD27 maintains clonally diverse CD8+ T cell responses of low antigen affinity to protect against viral variants KPJM van Gisbergen, PL Klarenbeek, NAM Kragten, PPA Unger, ... Immunity 35 (1), 97-108, 2011 | 162 | 2011 |
Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years PL Klarenbeek, EBM Remmerswaal, IJM Ten Berge, ME Doorenspleet, ... Public Library of Science 8 (9), e1002889, 2012 | 140 | 2012 |
Divergent SARS‐CoV‐2‐specific T‐and B‐cell responses in severe but not mild COVID‐19 patients AE Oja, A Saris, CA Ghandour, NAM Kragten, BM Hogema, EJ Nossent, ... European journal of immunology 50 (12), 1998-2012, 2020 | 139 | 2020 |
A central role for Notch in effector CD8+ T cell differentiation RA Backer, C Helbig, R Gentek, A Kent, BJ Laidlaw, CX Dominguez, ... Nature immunology 15 (12), 1143-1151, 2014 | 128 | 2014 |
The lipopolysaccharide biosynthesis locus of Campylobacter jejuni 81116 BN Fry, V Korolik, JA Ten Brinke, MTT Pennings, R Zalm, BJJ Teunis, ... Microbiology 144 (8), 2049-2061, 1998 | 118 | 1998 |
The clinical grade maturation cocktail monophosphoryl lipid A plus IFNγ generates monocyte-derived dendritic cells with the capacity to migrate and induce Th1 polarization A Ten Brinke, ML Karsten, MC Dieker, JJ Zwaginga, SM Van Ham Vaccine 25 (41), 7145-7152, 2007 | 114 | 2007 |
Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants: a cohort study L Wieske, KPJ van Dam, M Steenhuis, EW Stalman, LYL Kummer, ... The Lancet Rheumatology 4 (5), e338-e350, 2022 | 104 | 2022 |
Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes F Brasch, A Ten Brinke, G Johnen, M Ochs, N Kapp, KM Muller, MF Beers, ... American journal of respiratory cell and molecular biology 26 (6), 659-670, 2002 | 104 | 2002 |
Nuclear Receptors Nur77 and Nurr1 Modulate Mesenchymal Stromal Cell Migration MW Maijenburg, C Gilissen, SM Melief, M Kleijer, K Weijer, A Ten Brinke, ... Stem cells and development 21 (2), 228-238, 2012 | 93 | 2012 |
Human virus-specific effector-type T cells accumulate in blood but not in lymph nodes EBM Remmerswaal, SHC Havenith, MM Idu, EMM van Leeuwen, ... Blood, The Journal of the American Society of Hematology 119 (7), 1702-1712, 2012 | 88 | 2012 |
HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII SD van Haren, E Herczenik, A ten Brinke, K Mertens, J Voorberg, ... Molecular & Cellular Proteomics 10 (6), 2011 | 87 | 2011 |
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain E Herczenik, SD van Haren, A Wroblewska, P Kaijen, ... Journal of allergy and clinical immunology 129 (2), 501-509. e5, 2012 | 85 | 2012 |
Tolerogenic dendritic cell-based treatment for multiple sclerosis (MS): a harmonised study protocol for two phase I clinical trials comparing intradermal and intranodal cell … B Willekens, S Presas-Rodríguez, MJ Mansilla, J Derdelinckx, WP Lee, ... BMJ open 9 (9), e030309, 2019 | 75 | 2019 |
Detection of soluble human granzyme K in vitro and in vivo B Bade, J Lohrmann, A ten Brinke, AM Wolbink, GJ Wolbink, IJM Berge, ... European journal of immunology 35 (10), 2940-2948, 2005 | 71 | 2005 |
Clinical use of tolerogenic dendritic cells-harmonization approach in European collaborative effort A Ten Brinke, CMU Hilkens, N Cools, EK Geissler, JA Hutchinson, ... Mediators of Inflammation 2015, 2015 | 69 | 2015 |
Antigen-Specific B Cells Reactivate an Effective Cytotoxic T Cell Response against Phagocytosed Salmonella through Cross-Presentation J de Wit, Y Souwer, T Jorritsma, H Klaasse Bos, A ten Brinke, J Neefjes, ... PloS one 5 (9), e13016, 2010 | 66 | 2010 |